A conserved internal hydrophobic domain mediates the stable membrane integration of the dengue virus capsid protein

Virology

Volumn 233, Issue 1, 1997, Pages 105-117

  Markoff, Lewis ^a   Falgout, Barry ^a   Chang, Audrey ^a  

^a CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAPSID PROTEIN; RECOMBINANT DNA; SIGNAL PEPTIDE;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; DEGLYCOSYLATION; DENGUE VIRUS; HYDROPHOBICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN GLYCOSYLATION; VIRION; VIRUS CAPSID; VIRUS NUCLEOCAPSID; VIRUS PARTICLE;

DENGUE VIRUS; FLAVIVIRUS; MIRIDAE;

EID: 0030838369     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1997.8608     Document Type: Article

References (50)

1. Amberg S. M., Nestorowicz A., McCourt D. W., Rice C. M. NS2B-3 proteinase-mediated processing in the yellow fever virus structural region: In vitro and in vivo studies. J. Virol. 68:1994;3794-3802.
2. Bause E. Structural requirements for N-glycosylation of protein: Studies with proline peptides as conformational probes. Biochem. J. 209:1983;331-336.
3. Bause E., Legler G. The role of the hydroxy amino acid in the triplet sequence Asn-Xaa-Thr (Ser) for the N-glycosylation step during protein biosynthesis. Biochem. J. 195:1981;639-644.
4. Boyd D., Beckwith J. The role of charged amino acids in the localization of secreted and membrane proteins. Cell. 62:1990;1031-1033.
5. Castle E., Nowak T., Leidner U., Wengler G., Wengler G. Sequence analysis of the viral core protein and the membrane-associated proteins V1 and NV2 of the flavivirus West Nile virus and of the genome sequence for these proteins. Virology. 145:1985;227-236.
6. Chambers T. J., Grakoui A., Rice C. M. Processing of the yellow fever virus nonstructural polyprotein: A catalytically active NS3 proteinase domain and NS2B are required for cleavages at dibasic sites. J. Virol. 65:1991;6042-6050.
7. Chambers T. J., Hahn C. S., Galler R., Rice C. M. Flavivirus genome organization, expression, and replication. Annu. Rev. Microbiol. 44:1990;649-688.
8. Dalgarno L., Trent D. W., Strauss J. H., Rice C. M. Partial nucleotide sequence of the Murray Valley encephalitis virus genome: Comparison of the encoded polypeptides with yellow fever virus structural and non-structural proteins. J. Mol. Biol. 187:1986;309-323.
9. Deubel V., Kinney R. M., Trent D. W. Nucleotide sequence and deduced amino acid sequence of the structural proteins of dengue type 2 virus, Jamaica genotype. Virology. 155:1986;365-377.
10. Doms R. W., Lamb R. A., Rose J. K., Helenius A. Folding and assembly of viral membrane proteins. Virology. 193:1993;545-562.
11. Doyle C., Sambrook J., Gething M. J. Analysis of progressive deletions of transmembrane and cytoplasmic domains of the influenza hemagglutinin. J. Cell Biol. 103:1986;1193-1203.
12. Dupree P., Parton R. G., Raposo G., Kurzchalia T. V., Simons K. Caveolae and sorting in the trans Golgi network of epithelial cells. EMBO J. 12:1993;1597-1602.
13. Eisenberg D. Three-dimensional structure of membrane and surface proteins. Annu. Rev. Biochem. 53:1984;595-623.
14. Falgout B., Pethel M., Zhang Y.-M., Lai C.-J. Both nonstructural proteins NS2B and NS3 are required for the proteolytic cleavage of dengue virus nonstructural proteins. J. Virol. 65:1991;2467-2475.
15. Fujiki Y., Hubbard A. L., Fowler S., Lazarow P. B. Isolation of intracellular membranes by means of sodium carbonate treatment: Application to endoplasmic reticulum. J. Cell Biol. 93:1982;97-102.
16. Gibrat J., Garnier J., Robson B. Further developments of protein secondary structure prediction using information theory: New parameters and consideration of residue pairs. J. Mol. Biol. 198:1987;425-443.
17. Hartmann E., Rapaport T. A., Lodish H. F. Predicting the orientation of eukaryotic membrane-spanning proteins. Proc. Natl. Acad. Sci. USA. 86:1989;5786-5790.
18. 2. J. Cell Biol. 106:1988;1489-1498.
19. Kyte J., Doolittle R. F. A simple method for displaying the hydropathic character of a protein. J. Mol. Biol. 157:1982;105-132.
20. Mackow E., Makino Y., Zhao B. T., Zhang Y. M., Markoff L., Buckler-White A., Guiler M., Chanock R., Lai C.-J. The nucleotide sequence of dengue type 4 virus: Analysis of genes coding for non-structural proteins. Virology. 159:1987;217-228.
21. Mandl C. W., Heinz F. X., Kunz C. Sequence of the structural proteins of tick-borne encephalitis virus (Western subtype) and comparative analysis with other flaviviruses. Virology. 166:1988;197-205.
22. Mandl C. W., Holzmann H., Kunz C., Heinz F. X. Complete genomic sequence of Powassan virus: Evaluation of genetic elements in tick-borne versus mosquito-borne flaviviruses. Virology. 194:1993;173-184.
23. Mandl C. W., Iacono-Connors L., Wallner G., Holzmann H., Kunz C., Heinz F. X. Sequence of the genes encoding the structural proteins of the low-virulence tick-borne flaviviruses Langat TP21 and Yelantsev. Virology. 185:1991;891-895.
24. Markoff L. In vitro processing of flavivirus structural proteins: Cleavage of the premembrane protein. J. Virol. 63:1989;3345-3352.
25. Markoff L., Chang A., Falgout B. Processing of flavivirus structural proteins: Stable membrane insertion of premembrane requires the envelope signal peptide. Virology. 204:1994;526-540.
26. Markoff L. J., Lin B.-C., Sveda M. M., Lai C.-J. Glycosylation and surface expression of the influenza A neuraminidase requires the amino-terminal hydrophobic sequences. J. Mol. Cell. Biol. 4:1984;8-16.
27. Mason P. W., McAda P. C., Mason T. L., Fournier M. J. Sequence of the dengue-1 virus genome in the region encoding the three structural proteins and the major nonstructural protein NS1. Virology. 161:1987;262-267.
28. Moss B., Elroy-Stein O., Mizukami T., Alexander W. A., Fuerst T. R. New mammalian expression vectors. Nature. 348:1990;91-92.
29. Muller M. Proteolysis in protein import and export: Signal peptide processing in eu- and prokaryotes. Experientia. 48:1992;118-129.
30. Nowak T., Farber P. M., Wengler G., Wengler G. Analyses of the terminal sequences of West Nile virus structural proteins and of the in vitro translation of these proteins allow the proposal of a complete scheme of the proteolytic cleavages involved in their synthesis. Virology. 169:1989;365-376.
31. Osatomi K., Fuke I., Tsuru D., Shiba T., Sakaki Y., Sumiyoshi H. Nucleotide sequence of dengue type 3 virus genomic RNA encoding viral structural proteins. Virus Genes. 2:1988;99-108.
32. Parks G. D., Lamb R. A. Topology of eukaryotic type II membrane proteins: Importance of N-terminal positively charged residues flanking the hydrophobic domain. Cell. 64:1991;777-787.
33. Parton R. G., Simons K. Digging into caveolae. Science. 269:1995;1398-1399.
34. Randolph V. B., Winkler G., Stollar V. Acidotropic amines inhibit proteolytic processing of flavivirus prM protein. Virology. 174:1990;450-458.
35. Rice C. M., Lenches E. M., Eddy S. R., Shin S. J., Sheets R. L., Strauss J. H. Nucleotide sequence of yellow fever virus: Implications for flavivirus gene expression and evolution. Science. 229:1985;726-733.
36. Ruiz-Linares A., Cahour A., Despres P., Girard M., Bouloy M. Processing of yellow fever virus structural protein: Role of cellular proteases in maturation of the structural proteins. J. Virol. 63:1989;4199-4209.
37. Schagger H., Von Jagow G. Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Anal. Biochem. 166:1987;368-379.
38. Speight G., Coia G., Parker M. D., Westaway E. G. Gene mapping and positive identification of the nonstructural proteins NS2A, NS2B, NS3, NS4B, and NS5 of the flavivirus Kunjin and their cleavage sites. J. Gen. Virol. 69:1988;23-34.
39. K. Stadler, S. L. Allison, C. Kunz, F. X. Heinz, 1995, Abstracts of the Fourth International Symposium on Positive Strand RNA Viruses, 61.
40. Sumiyoshi H., Mori C., Fuke I., Morita K., Kuhara S., Kondou J., Kikuchi Y., Nagamatu H., Igarashi A. Complete nucleotide sequence of the Japanese encephalitis virus genome RNA. Virology. 161:1987;497-510.
41. Trent D. W., Kinney R. M., Johnson B. J. B., Vorndam A. V., Grant J. A., Deubel V., Rice C. M., Hahn C. Partial nucleotide sequence of St. Louis encephalitis virus RNA: Structural proteins, NS1, ns2a, and ns2b. Virology. 156:1987;293-304.
42. R. Venable, S. Feller, R. Pastor.
43. von Heijne G. A new method for predicting signal sequence cleavage sites. Nucleic Acids Res. 14:1986;4683-4690.
44. von Heijne G. Transcending the impenetrable: How proteins come to terms with membranes. Biochim. Biophys. Acta. 947:1988;307-333.
45. von Heijne G. Control of topology and mode of assembly of a polytopic membrane protein by positively charged residues. Nature. 341:1989;456-458.
46. von Heijne G. The signal peptide. J. Membr. Biol. 115:1990;195-201.
47. Walter P., Lingappa V. R. Mechanism of protein translocation across the endoplasmic reticulum membrane. Annu. Rev. Cell Biol. 2:1986;499-516.
48. Yamshchikov V. F., Compans R. W. Processing of the intracellular form of the West Nile virus capsid protein by the viral NS2B-NS3 protease: An in vitro study. J. Virol. 68:1994;5765-5771.
49. Yamshchikov V. F., Compans R. W. Formation of the flavivirus envelope: Role of the viral NS2B-NS3. J. Virol. 69:1995;1995-2003.
50. Zhao B., Mackow E., Buckler-White A., Markoff L., Chanock R. M., Lai C.-J., Makino Y. Cloning full-length dengue type 4 viral DNA sequences, analysis of genes coding for structural proteins. Virology. 155:1986;77-88.