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Volumn 110, Issue 16, 1997, Pages 1839-1849

Megalomicin disrupts lysosomal functions

Author keywords

Endosomal lysosomal fusion; Endosome; Intracellular trafficking; Lysosome; Megalomicin; V H+ ATPase inhibitor

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; MACROLIDE; MEGALOMICIN; OVALBUMIN; SIALOGLYCOPROTEIN; T LYMPHOCYTE RECEPTOR;

EID: 0030838176     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (10)

References (42)
  • 1
    • 0026029851 scopus 로고
    • The CD3-famma and CD3-delta subunits of the T cell antigen receptor can be expressed within distinct functional TCR/CD3 complexes
    • Alarcón, B., Ley, S. C., Sanchez Madrid, F., Blumberg, R. S., Ju, S. T., Fresno, M. and Terhorst, C. (1991). The CD3-famma and CD3-delta subunits of the T cell antigen receptor can be expressed within distinct functional TCR/CD3 complexes. EMBO J. 10. 903-912.
    • (1991) EMBO J. , vol.10 , pp. 903-912
    • Alarcón, B.1    Ley, S.C.2    Sanchez Madrid, F.3    Blumberg, R.S.4    Ju, S.T.5    Fresno, M.6    Terhorst, C.7
  • 2
    • 0023645661 scopus 로고
    • Definition of IgG- And albumin-binding regions of streptococcal protein B
    • Akerström. B., Nielsen, F., and Björck, L. (1987). Definition of IgG- and albumin-binding regions of streptococcal protein B. J. Biol. Chem. 262. 13388-13391.
    • (1987) J. Biol. Chem. , vol.262 , pp. 13388-13391
    • Akerström, B.1    Nielsen, F.2    Björck, L.3
  • 3
    • 0029869843 scopus 로고    scopus 로고
    • An endosomal beta COP is involved in the pH-dependent formation of transport vesicles destined for late endosomes
    • Aniento, F., Gu, F., Parton, R. G. and Gruenberg. J. (1996). An endosomal beta COP is involved in the pH-dependent formation of transport vesicles destined for late endosomes. J. Cell Biol. 133. 29-41.
    • (1996) J. Cell Biol. , vol.133 , pp. 29-41
    • Aniento, F.1    Gu, F.2    Parton, R.G.3    Gruenberg, J.4
  • 4
    • 0023661002 scopus 로고
    • Snbunit composition and ATP site labeling of the coated vesicle proton-translocating adenosinetriphosphatase
    • Arai, H., Berne, M., Terres, G., Terres, H., Puopolo, K. and Forgac, M. (1987). Snbunit composition and ATP site labeling of the coated vesicle proton-translocating adenosinetriphosphatase. Biochemistry 26. 6632-6638.
    • (1987) Biochemistry , vol.26 , pp. 6632-6638
    • Arai, H.1    Berne, M.2    Terres, G.3    Terres, H.4    Puopolo, K.5    Forgac, M.6
  • 5
    • 0022894660 scopus 로고
    • Biosynthesis. glycosylation, movement through the Golgi system, and transport to lysosomes by an N-linked carbohydrate-independent mechanism of three lysosomal integral membrane proteins
    • Barriocanal J. G., Bonifacino J. S., Yuan, I., and Sandoval, I. V. (1986). Biosynthesis. glycosylation, movement through the Golgi system, and transport to lysosomes by an N-linked carbohydrate-independent mechanism of three lysosomal integral membrane proteins. J. Biol. Chem. 261. 16755-16763.
    • (1986) J. Biol. Chem. , vol.261 , pp. 16755-16763
    • Barriocanal, J.G.1    Bonifacino, J.S.2    Yuan, I.3    Sandoval, I.V.4
  • 7
    • 0025904178 scopus 로고
    • Purification and characterization of a novel broad-specifictly (α 1-2, α 1-3 and α 1-6) mannosidase from rat liver
    • Bonay, P. and Hughes, R. C. (1991). Purification and characterization of a novel broad-specifictly (α 1-2, α 1-3 and α 1-6) mannosidase from rat liver. Eur. J. Biochem. 197. 229-238.
    • (1991) Eur. J. Biochem. , vol.197 , pp. 229-238
    • Bonay, P.1    Hughes, R.C.2
  • 8
    • 0029671096 scopus 로고    scopus 로고
    • Intra-Golgi transport inhibition by megalomicin
    • Bonay P., Munro, S., Fresno, M. and Alarcon, B. (1996). Intra-Golgi transport inhibition by megalomicin. J. Biol. Chem. 271, 3719-3726
    • (1996) J. Biol. Chem. , vol.271 , pp. 3719-3726
    • Bonay, P.1    Munro, S.2    Fresno, M.3    Alarcon, B.4
  • 9
    • 0024345717 scopus 로고
    • Pre-Golgi degradation of newly synthesized T cell antigen receptor chains: Intrinsic sensitivity and the role of suhunit assembly
    • Bonifacino, J. S., Suzuki, C. K., Lippincott-Schwartz, J., Weissman, A. M. and Klausner, R. D. (1989). Pre-Golgi degradation of newly synthesized T cell antigen receptor chains: Intrinsic sensitivity and the role of suhunit assembly. J. Cell Biol. 109. 73-83.
    • (1989) J. Cell Biol. , vol.109 , pp. 73-83
    • Bonifacino, J.S.1    Suzuki, C.K.2    Lippincott-Schwartz, J.3    Weissman, A.M.4    Klausner, R.D.5
  • 10
    • 0011913143 scopus 로고
    • Batilomycins: A class of inhibitors of membrane ATPases from microorganisms, animal cells, and plant cells
    • Bowman, E. J., Siebers, A. and Altendorf, K. (1988). Batilomycins: a class of inhibitors of membrane ATPases from microorganisms, animal cells, and plant cells. Proc. Nat. Acad. Sci. USA 85. 7972-7976.
    • (1988) Proc. Nat. Acad. Sci. USA , vol.85 , pp. 7972-7976
    • Bowman, E.J.1    Siebers, A.2    Altendorf, K.3
  • 11
    • 0029148577 scopus 로고
    • The role for phosphatidylinositol-3-kinase in the sorting and transport of newly synthesized lysosomal enzymes in mammalian cells
    • Brown, W. D., Dewald, D. W., Emr, S. D., Puttner H. and Balch. W. E. (1995). The role for phosphatidylinositol-3-kinase in the sorting and transport of newly synthesized lysosomal enzymes in mammalian cells. J. Cell Biol. 130. 781-796.
    • (1995) J. Cell Biol. , vol.130 , pp. 781-796
    • Brown, W.D.1    Dewald, D.W.2    Emr, S.D.3    Puttner, H.4    Balch, W.E.5
  • 13
    • 0024260833 scopus 로고
    • Selective degradation of T cell antigen receptor chains retained in a pre-Golgi compartment
    • Chen, C., Bonifacino, J. S., Yuan, L. C. and Klausner, R. D. (1988) Selective degradation of T cell antigen receptor chains retained in a pre-Golgi compartment. J. Cell Biol. 107. 2149-2161.
    • (1988) J. Cell Biol. , vol.107 , pp. 2149-2161
    • Chen, C.1    Bonifacino, J.S.2    Yuan, L.C.3    Klausner, R.D.4
  • 14
  • 15
    • 0028172714 scopus 로고
    • Mammalian alpha-mannosidases-multiple forms but a common purpose
    • Daniel, P. F., Winchester, B. and Warren, C. D. (1994). Mammalian alpha-mannosidases-multiple forms but a common purpose? Glycobiology 4. 551-566.
    • (1994) Glycobiology , vol.4 , pp. 551-566
    • Daniel, P.F.1    Winchester, B.2    Warren, C.D.3
  • 16
    • 0023608161 scopus 로고
    • Chinese hamster ovary cell lysosomes rapidly exchange contents
    • Ferris, A. L., Brown, J. C., Park, R. D. and Storrie, B. (1987) Chinese hamster ovary cell lysosomes rapidly exchange contents. J. Cell Biol. 105. 2703-2712.
    • (1987) J. Cell Biol. , vol.105 , pp. 2703-2712
    • Ferris, A.L.1    Brown, J.C.2    Park, R.D.3    Storrie, B.4
  • 19
    • 0024410381 scopus 로고
    • Sorting and traffic in the central vacuolar system
    • Klausner, R. D. (1989). Sorting and traffic in the central vacuolar system. Cell 57. 703-706.
    • (1989) Cell , vol.57 , pp. 703-706
    • Klausner, R.D.1
  • 20
    • 0025971630 scopus 로고
    • T Cell I antigen receptor activation pathways: The tyrosine kinase connection
    • Klausner, R. D. and Samelson, L. E. (1991). T Cell I antigen receptor activation pathways: The tyrosine kinase connection. Cell 64. 875-878.
    • (1991) Cell , vol.64 , pp. 875-878
    • Klausner, R.D.1    Samelson, L.E.2
  • 21
    • 0025041029 scopus 로고
    • Protein degradation in the endoplasmic reticulum
    • Klausner, R. D. and Sitia, R. (1990). Protein degradation in the endoplasmic reticulum. Cell 62. 611-614.
    • (1990) Cell , vol.62 , pp. 611-614
    • Klausner, R.D.1    Sitia, R.2
  • 22
    • 0018750572 scopus 로고
    • Specific absorption of human serum albumin, immunoglobulin A. and immunoglobulin G with selected strains of group A and G streptococci
    • Kronvall, G., Simmons, A., Myhre, K. B. and Jonsson, S. (1979) Specific absorption of human serum albumin, immunoglobulin A. and immunoglobulin G with selected strains of group A and G streptococci. Infect. Immun. 25. 1-10.
    • (1979) Infect. Immun. , vol.25 , pp. 1-10
    • Kronvall, G.1    Simmons, A.2    Myhre, K.B.3    Jonsson, S.4
  • 23
    • 0023749075 scopus 로고
    • Degradation from the endoplasmic reticulum newly synthesized proteins
    • Lippincott-Schwartz, J., Bonifacino, J. S., Yuan, L. C. and Klausner, R. D. (1988). Degradation from the endoplasmic reticulum newly synthesized proteins. Cell 54. 209-220.
    • (1988) Cell , vol.54 , pp. 209-220
    • Lippincott-Schwartz, J.1    Bonifacino, J.S.2    Yuan, L.C.3    Klausner, R.D.4
  • 25
    • 0026651925 scopus 로고
    • An endoplasmic reticulum retention signal in the CD3 epsilon chain of the T-cell receptor
    • Mallabiabarrena, A., Kresno, M. and Alarcon, B. (1992) An endoplasmic reticulum retention signal in the CD3 epsilon chain of the T-cell receptor. Nature 357. 593-596.
    • (1992) Nature , vol.357 , pp. 593-596
    • Mallabiabarrena, A.1    Kresno, M.2    Alarcon, B.3
  • 26
    • 0022555867 scopus 로고
    • Acidification of the endocytic and exocytic pathways
    • Mellman, I., Fuchs, R. and Helenius, A. (1986). Acidification of the endocytic and exocytic pathways. Annn. Rev. biochem. 55. 663-700.
    • (1986) Annn. Rev. Biochem. , vol.55 , pp. 663-700
    • Mellman, I.1    Fuchs, R.2    Helenius, A.3
  • 27
    • 0025240867 scopus 로고
    • Alteration of intracellular traffic by monensin. mechanism, specilicity and relationship to toxicily
    • Mollenhauer, H. H., Morre, D. J. and Rowe, L. D. (1990) Alteration of intracellular traffic by monensin. mechanism, specilicity and relationship to toxicily. Biochim. Biophys. Acta 1031. 225-246.
    • (1990) Biochim. Biophys. Acta , vol.1031 , pp. 225-246
    • Mollenhauer, H.H.1    Morre, D.J.2    Rowe, L.D.3
  • 29
    • 0024962604 scopus 로고
    • +-ATPase and its subunit structures
    • +-ATPase and its subunit structures. J. Biol. Chem. 264. 18445-18450.
    • (1989) J. Biol. Chem. , vol.264 , pp. 18445-18450
    • Moriyama, Y.1    Nelson, N.2
  • 30
    • 0024550743 scopus 로고
    • The evolution of H-ATPases
    • Nelson, N. and Taiz, I. (1989). The evolution of H-ATPases. Trends Biochem. Sci. 14. 113-116.
    • (1989) Trends Biochem. Sci. , vol.14 , pp. 113-116
    • Nelson, N.1    Taiz, I.2
  • 31
    • 0007010827 scopus 로고
    • Receptor-medated endocytosis and lysosomal transport
    • ed. A. I. Magee and T. Wileman. Oxford University Press. New York
    • Nolan, C. M. (1992). Receptor-medated endocytosis and lysosomal transport. In Protein Targetting: a Practical Approach (ed.) A. I. Magee and T. Wileman). pp. 1-23. Oxford University Press. New York.
    • (1992) Protein Targetting: a Practical Approach , pp. 1-23
    • Nolan, C.M.1
  • 32
    • 0027489133 scopus 로고
    • Sorting of membrane proteins in the secretory pathway
    • Pelham, H. R. and Munro, S. (1993). Sorting of membrane proteins in the secretory pathway. Cell 75. 603-605.
    • (1993) Cell , vol.75 , pp. 603-605
    • Pelham, H.R.1    Munro, S.2
  • 33
    • 0025947144 scopus 로고
    • A conformational epitope expressed upon association of CD3-ε with either CD3-δ or CD3-γ is the main target for recognition by anti-CD3 monoclonal antibodies
    • Salmerón, A., Sánchez-Madrid, F., Ursa, M. A., Kresno, M. and Alarcón, B. (1991). A conformational epitope expressed upon association of CD3-ε with either CD3-δ or CD3-γ is the main target for recognition by anti-CD3 monoclonal antibodies. J. Immunol. 147. 3047-3052.
    • (1991) J. Immunol. , vol.147 , pp. 3047-3052
    • Salmerón, A.1    Sánchez-Madrid, F.2    Ursa, M.A.3    Kresno, M.4    Alarcón, B.5
  • 34
    • 0023830811 scopus 로고
    • Iwo distinct subpopulations of endosomes involved in membrane recycling and transport to lysosomes
    • Schmid, S. L., Fuchs, R., Male, P. and Mellman, I. (1988). Iwo distinct subpopulations of endosomes involved in membrane recycling and transport to lysosomes. Cell 52. 73-83.
    • (1988) Cell , vol.52 , pp. 73-83
    • Schmid, S.L.1    Fuchs, R.2    Male, P.3    Mellman, I.4
  • 35
    • 0023178717 scopus 로고
    • Substrate specificities of rat kidney lysosomal and cytosolic alpha-D-mannosidases and effects of swainsonine suggest a role of the cytosolic enzyme in glycoprotein catabolism
    • Tulsiani, D. R. and Touster, O. (1987). Substrate specificities of rat kidney lysosomal and cytosolic alpha-D-mannosidases and effects of swainsonine suggest a role of the cytosolic enzyme in glycoprotein catabolism. J. Biol. Chem. 262. 6506-6514.
    • (1987) J. Biol. Chem. , vol.262 , pp. 6506-6514
    • Tulsiani, D.R.1    Touster, O.2
  • 36
    • 0025649278 scopus 로고
    • The cytotoxic action of diphtheria toxin and its degradation in intact Vero cells are inhibited by bafilomycin A1, a specific inhibitor of vacuolar-type H(+)-ATPase
    • Umata, T., Moriyama, V., Futai, M. and Mekada, K. (1990). The cytotoxic action of diphtheria toxin and its degradation in intact Vero cells are inhibited by bafilomycin A1, a specific inhibitor of vacuolar-type H(+)-ATPase. J. Biol. Chem. 265. 21940-21945.
    • (1990) J. Biol. Chem. , vol.265 , pp. 21940-21945
    • Umata, T.1    Moriyama, V.2    Futai, M.3    Mekada, K.4
  • 37
    • 0029160297 scopus 로고
    • Transport from late endosomes to lysosomes, but not sorting of integral membrane proteins in endosomes, depends on the vacuolar proton pump
    • van Weert, A. W., Dunn, K. W., Gueze, H. J., Maxfield, F. R. and Stoorvogel, W. (1995). Transport from late endosomes to lysosomes, but not sorting of integral membrane proteins in endosomes, depends on the vacuolar proton pump. J. Cell Biol. 130. 821-834.
    • (1995) J. Cell Biol. , vol.130 , pp. 821-834
    • Van Weert, A.W.1    Dunn, K.W.2    Gueze, H.J.3    Maxfield, F.R.4    Stoorvogel, W.5
  • 38
    • 0025193361 scopus 로고
    • The γ and ε suhunits of the CD3 complex inhibit pre-Golgi degradation of newly synthesized T cell antigen receptors
    • Wileman, T., Carson, G. R., Concino, M., Ahmed, A. and Terhorst, C. (1990a). The γ and ε suhunits of the CD3 complex inhibit pre-Golgi degradation of newly synthesized T cell antigen receptors. J. Cell Biol. 110. 973-986.
    • (1990) J. Cell Biol. , vol.110 , pp. 973-986
    • Wileman, T.1    Carson, G.R.2    Concino, M.3    Ahmed, A.4    Terhorst, C.5
  • 39
    • 0025163934 scopus 로고
    • Recognition for degradation in the endoplasmic reliculum and lysosomes prevents the transport of single TCR beta and CD3 delta subunits of the T-cell antigen receptor to the surface of cells
    • Wileman, T., Pettey, C. and Terhorst, C. (1990b) Recognition for degradation in the endoplasmic reliculum and lysosomes prevents the transport of single TCR beta and CD3 delta subunits of the T-cell antigen receptor to the surface of cells. Int. Immunol. 2. 743-754.
    • (1990) Int. Immunol. , vol.2 , pp. 743-754
    • Wileman, T.1    Pettey, C.2    Terhorst, C.3
  • 40
    • 0026635751 scopus 로고
    • Inhibition of the acidification of endosomes and Iysosomes by the antibiotic concanamycin B in macrophage J774
    • Woo, J.-T., Shinohara, C., Sakai, K., Hasumi, K. and Endo, A. (1992) Inhibition of the acidification of endosomes and Iysosomes by the antibiotic concanamycin B in macrophage J774. Eur. J. Biochem. 207. 383-389.
    • (1992) Eur. J. Biochem. , vol.207 , pp. 383-389
    • Woo, J.-T.1    Shinohara, C.2    Sakai, K.3    Hasumi, K.4    Endo, A.5
  • 41
    • 0022978965 scopus 로고
    • Isolation and reconstitution of the clathrin-coated vesicle proton translocating complex
    • Xie, X. S. and Stone, D. K. (1986). Isolation and reconstitution of the clathrin-coated vesicle proton translocating complex. J. Biol. Chem. 261. 2492-2495.
    • (1986) J. Biol. Chem. , vol.261 , pp. 2492-2495
    • Xie, X.S.1    Stone, D.K.2


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