Efficacy and tolerability of amlodipine in patients with stable angina pectoris. Results of a multicentre study

Clinical Drug Investigation

Volumn 13, Issue SUPPL. 1, 1997, Pages 149-155

  Perna, G P ^a   De Luca, G ^a   Stanislao, M ^a   Vigna, C ^a   Gallucci, M ^b  

^a CASA SOLLIEVO DELLA SOFFERENZA HOSPITAL   (Italy)

^b SGiovanni Hospital Agency   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AMLODIPINE;

ADULT; AGED; ANGINA PECTORIS; ARTICLE; ASTHENIA; CLINICAL TRIAL; DRUG EFFICACY; DRUG TOLERABILITY; EDEMA; ERGOMETRY; EXERCISE TEST; EXERCISE TOLERANCE; FEMALE; HEADACHE; HEART RATE; HOT FLUSH; HUMAN; MAJOR CLINICAL STUDY; MALE; MEAN ARTERIAL PRESSURE; MULTICENTER STUDY; NAUSEA; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; SIDE EFFECT; ST SEGMENT DEPRESSION; THORAX PAIN; VERTIGO;

EID: 0030837893     PISSN: 11732563     EISSN: None     Source Type: Journal    
DOI: 10.2165/00044011-199700131-00026     Document Type: Article

References (14)

1. Matlib MA, French JF, Grupp L, et al. Vasodilatory action of amlodipine on rat aorta, pig coronary artery, human coronary artery and on isolated Langendorff rat heart preparation. J Cardiovasc Pharmacol 1988; 12 Suppl. 7: S50-4
2. Perondi R, Saino A, Zanchetti A, et al. Coronary vascular reactivity and calcium antagonist therapy in patients with angina. J Cardiovasc Pharmacol 1994; 24 Suppl. A: S30-6
3. Opie LH. Profiles of calcium antagonists in cardiovascular disease with special reference to second generation agents and amlodipine. Postgrad Med J 1991; 67 Suppl. 5: S2-8
4. Abernethy DR, Gutkowska J, Winterbottom LM. Effects of amlodipine, a long-acting dihydropyridine calcium antagonist in aging hypertension: pharmacodynamics in relation to disposition. Clin Pharmacol Ther 1990; 48: 76-86
5. Laher MS, Kelly JG, Doyle GD, et al. Pharmacokinetics of amlodipine in renal impairment. Cardiovasc Pharmacol 1991; 17 Suppl. 1: S13-5
6. Abernethy DR. Amlodipine: pharmacokinetic profile of a low-clearance calcium antagonist. J Cardiovasc Pharmacol 1991; 17 Suppl. 1: S4-7
7. Faulkner JK, McGibney D, Chasseaud LF, et al. The pharmacokinetics of amlodipine in healthy volunteers after single intravenous and oral doses and after 14 repeated oral doses given once daily. Br J Clin Pharmac 1986; 22: 21-5
8. Nayler WG, Gu XH. Protecting the vasculature: an eye toward the future. Am J Cardiol 1990; 66: 23-7
9. Bernini F, Bertulli SM. Effect of the dihydropyridine calcium antagonist amlodipine on 'in vitro' metabolism of low density lipoproteins. 4th International Symposium on Calcium Antagonists: Pharmacology and Clinical Research [abstract]. 1989 May 25-27; Florence
10. Paoletti R, Bernini F. A new generation of calcium antagonists and their role in atherosclerosis. Am J Cardiol 1990; 66: 28-31H
11. Sonnenblick EH, Ross Jr J, Braunwald E. Oxygen consumption of the heart: newer concepts of its multifactorial determination. Am J Cardiol 1968; 22: 328-36
12. Kitamura K, Jorgensen CR, Gobel FL, et al. Hemodynamic correlates of myocardial oxygen consumption during upright exercise. J Appl Physiol 1972; 32: S16-22
13. Nelson RR, Fredarick GL, Jorgensen CR, et al. Hemodynamic predictors of myocardial oxygen consumption during static and dynamic exercise. Circulation 1974; 50: 1179-89
14. Fisher M, Girotta S. New uses for calcium channel blockers: therapeutic implications. Drugs 1993; 46 (6): 961-75