Neuromuscular activity and upper airway collapsibility : Mechanisms of action in the decerebrate cat

American Journal of Respiratory and Critical Care Medicine

Volumn 156, Issue 2 I, 1997, Pages 515-521

  Rowley, James A ^a,b   Williams, Bernesta C ^a   Smith, Philip L ^a   Schwartz, Alan R ^a  

^a DEPARTMENT OF PATHOLOGY   (United States)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; DECEREBRATION; DRUG MECHANISM; END TIDAL CARBON DIOXIDE TENSION; HYPERCAPNIA; HYPOGLOSSAL NERVE; MALE; NEUROMUSCULAR FUNCTION; NONHUMAN; PRIORITY JOURNAL; TONGUE; TRACHEA INJURY; UPPER RESPIRATORY TRACT;

EID: 0030835778     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.156.2.9607115     Document Type: Article

References (26)

1. Kuna, S. T., and G. Sant'Ambrogio. 1991. Pathophysiology of upper airway closure during sleep. J.A.M.A. 266:1384-1389.
2. Rowley, J. A., S. Permutt, S. J. Willey, P. L. Smith, and A. R. Schwartz. 1996. Effect of tracheal and tongue displacement on upper airway airflow dynamics. J. Appl. Physiol. 80:2171-2178.
3. Thut, D. C., A. R. Schwartz, D. Roach, R. A. Wise, S. Permutt, and P. L. Smith. 1993. Tracheal and neck position influence upper airway airflow dynamics by altering airway length. J. Appl. Physiol. 75:2084-2090.
4. Remmers, J. E., W. J. DeGroot, E. K. Sauerland, and A. M. Anch. 1978. Pathogenesis of upper airway occlusion during sleep. J. Appl. Physiol.: Respirat. Environ. Exercise Physiol. 44:931-938.
5. Megirian, D., C. F. L. Hinrichsen, and J. H. Sherrey. 1985. Respiratory roles of genioglossus, sternothyroid, and sternohyoid muscles during sleep. Exp. Neurol. 90:118-128.
6. van de Graaff, W. B., S. B. Gottfried, J. Mitra, E. van Lunteren, N. S. Cherniack, and K. P. Strohl. 1984. Respiratory functions of hyoid muscles and hyoid arch. J. Appl. Physiol. 57:197-204.
7. Brouillette, R. T., and B. T. Thach. 1980. Control of genioglossus muscle inspiratory activity. J. Appl. Physiol.: Respirat. Environ. Exercise Physiol. 49:801-808.
8. Haxhiu, M. A., E. van Lunteren, J. Mitra, and N. S. Cherniack. 1984. Responses to chemical stimulation of upper airway muscles and diaphragm in awake cats. J. Appl. Physiol.: Respirat. Environ. Exercise Physiol. 56:397-403.
9. Kirsten, E. B., and W. M. St. John. 1978. A feline decerebration technique with low mortality and long-term homeostasis. J. Pharmacol. Methods 1:263-268.
10. Seelagy, M. M., A. R. Schwartz, D. B. Russ, E. D. King, R. A. Wise, and P. L. Smith. 1994. Reflex modulation of airflow dynamics through the upper airway. J. Appl. Physiol. 76:2692-2700.
11. 2. J. Appl. Physiol. 74: 1597-1605.
12. Strohl, K. P., and J. M. Fouke. 1985. Dilating forces on the upper airway of anesthetized dogs. J. Appl. Physiol. 58:452-458.
13. Rothstein, R. J., S. L. Narce, B. deBerry-Borowiecki, and R. H. I. Blanks. 1983. Respiratory-related activity of upper airway muscles in anesthetized rabbit. J. Appl. Physiol. 55:1830-1836.
14. Roberts, J. L., W. R. Reed, and B. T. Thach. 1984. Pharyngeal airway-stabilizing function of sternohyoid and sternothyroid muscles in the rabbit. J. Appl. Physiol.: Respirat. Environ. Exercise Physiol. 57:1790-1795.
15. van de Graaff, W. B. 1991. Thoracic traction on the trachea: mechanisms and magnitude. J. Appl. Physiol. 70:1328-1336.
16. Abd-el-Malek, S. 1938. A contribution to the study of the movements of the tongue in animals, with special reference to the cat. J. Anal. 73:15-30.
17. Weiner, D., J. Mitra, J. Salamone, and N. S. Cherniack. 1982. Effect of chemical stimuli on nerves supplying upper airway muscles. J. Appl. Physiol.: Respirat. Environ. Exercise Physiol. 52:530-536.
18. Onal, E., M. Lopata, and T. D. O'Connor. 1981. Diaphragmatic and genioglossal electromyogram responses to CO2 rebreathing in humans. J. Appl. Physiol.: Respirat. Environ. Exercise Physiol. 50:1052-1055.
19. Mitra, J., N. R. Prabhakar, M. A. Haxhiu, and N. S. Cherniack. 1986. Comparison of the effects of hypercapnia on phrenic and hypoglossal activity in anesthetized decerebrate and decorticate animals. Brain Res. Bull. 17:181-187.
20. Schwartz, A. R., D. C. Thut, D. B. Russ, M. M. Seelagy, X. Yuan, R. G. Brower, S. Permutt, R. A. Wise, and P. L. Smith. 1993. Effect of electrical stimulation of the hypoglossal nerve on airflow mechanics in the isolated upper airway. Am. Rev. Respir. Dis. 147:1144-1150.
21. van Lunteren, E., and K. P. Strohl. 1986. The muscles of the upper airway. Clin. Chest Med. 7:171-188.
22. Kuna, S. T. 1995. Effect of hypercapnia on pharyngeal constrictor (PC) activity in decerebrate cats (abstract). Am. J. Respir. Crit. Care Med. 151:A556.
23. van der Touw, T., N. O'Neill, A. Brancatisano, T. Amis, J. R. Wheatley, and L. A. Engel. 1994. Respiratory-related activity of soft palate muscles: augmentation by negative upper airway pressure. J. Appl. Physiol. 76:424-432.
24. Kogo, M., T. Kurimoto, H. Koizumi, J. Nishio, and T. Matsuya. 1992. Respiratory activities in relation to palatal muscle contraction. Cleft Palate Craniofac. J. 29:174-178.
25. English, P. W., C. R. Vanoye, and S. T. Kuna. 1995. Respiratory-related palatopharyngeus activity in normal adult humans (abstract). Am. J. Respir. Crit. Care Med. 151:A557.
26. Mortimore, I. L., R. Mathur, and N. J. Douglas. 1994. Effect of posture and negative pressure application on levator palatini and palatoglossus muscle activity (abstract). Am. J. Respir. Crit. Care Med. 149: A145.