Delayed gastric emptying during interferon-α therapy in patients with chronic Hepatitis C: Relief by cisapride

Scandinavian Journal of Gastroenterology

Volumn 32, Issue 6, 1997, Pages 547-551

  Nishibayashi, H ^a   Kanayama, S ^a   Shinomura, Y ^a   Kawata, S ^a   Matsuzawa, Y ^a  

^a OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

Abdominal symptom; Cisapride; Gastric emptying; Interferon sulfamethizole

Indexed keywords

ALPHA INTERFERON; CISAPRIDE; RECOMBINANT ALPHA INTERFERON; TECHNETIUM 99M;

ABDOMINAL DISCOMFORT; ADULT; ANOREXIA; ARTICLE; CHRONIC HEPATITIS; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; HEPATITIS C; HUMAN; IMMUNOTHERAPY; INTRAMUSCULAR DRUG ADMINISTRATION; MALE; NAUSEA; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; STOMACH EMPTYING; STOMACH FUNCTION DISORDER; STOMACH MOTILITY; STOMACH SCINTISCANNING;

EID: 0030835295     PISSN: 00365521     EISSN: None     Source Type: Journal    
DOI: 10.3109/00365529709025097     Document Type: Article

References (19)

1. Baron S, Stephen SK, Fleischmann WR, Coppenhaver DH, Niesel DW, Klimpel GR. The interferons: mechanisms of action and clinical applications. JAMA 1991;266:1375-83.
2. Davis GL, Balart LA, Schiff ER, Lindsay K, Bodenheimer HC, Perrilo RP, et al. Treatment of chronic hepatitis C with recombinant interferon alfa: a multicenter randomized, controlled trial. N Engl J Med 1989;321:1501-6.
3. Sainokami S, Hino K, Shimoda K, Hirohumi N. Clinical analysis of patients with chronic hepatitis C who discontinued interferon treatment because of side effects: our experiences and recent reports. Jpn J Clin Med 1994;52:1889-94.
4. Barbara L, Camilleri R, Corinaldesi R, Crean GP, Heading RC, Johnson AG, et al. Definition and investigation of dyspepsia: consensus of an international ad hoc working party. Dig Dis Sci 1989;34:1272-6.
5. Taniyama K, Nakayama S, Takeda K, Matsuyama S, Shirakawa J, Sano I, et al. Cisapride stimulates motility of the intestine via the 5-hydroxytryptamine receptors. J Pharmacol Exp Ther 1991;258:1098-104.
6. Jian R, Durcot F, Ruskone A, Chaussade S, Rambaud JC, Modigliani R, et al. Symptomatic radionuclide and therapeutic assessment of chronic idiopathic dyspepsia: a double-blind placebo-controlled evaluation of cisapride. Dig Dis Sci 1989; 34:657-64.
7. Van Outryve M, De Nutte N, Van Eeghem P, Gooris JP. Efficacy of cisapride in functional dyspepsia resistant to domperidone or metoclopramide: a double-blind placebocontrolled study. Scand J Gastroenterol 1993;28 Suppl 195: 47-53.
8. Asada T, Murakami M, Sako Y, Fukushima Y, Yonekura Y, Konishi J, et al. Sulfamethizole capsule method: a new method for assessing gastric emptying of solids. Dig Dis Sci 1994;39: 2056-61.
9. Gochin R, Kanfer I, Haigh JM. Simultaneous determination of trimethoprim, sulphamethoxazole and N-acetylsulphamethoxazole in serum and urine by high-performance liquid chromatography. J Chromatogr 1981;223:139-45.
10. Kroop HS, Long WB, Alavi A, Hansell J. Effect of water and fat on gastric emptying of solid meals. Gastroenterology 1979;77: 997-1000.
11. Christian PE, Datz FL, Sorenson JA, Taylor A. Technical factors in gastric emptying studies. J Nucl Med 1983;24:264-8.
12. Isobe H, Sakai H, Satoh M, Sakamoto S, Nawata H. Delayed gastric emptying in patients with liver cirrhosis. Dig Dis Sci 1994;39:983-7.
13. Wingate DL. Intrinsic and extrinsic neural control. In: Kumar D, Wingate D, editors. An illustrated guide to gastrointestinal motility. Edinburgh: Churchill Livingstone, 1993:64-77.
14. Tache Y, Maeda-Hagiwara M, Turkelson CM. Central nervous action of corticotropin-releasing factor to inhibit gastric emptying in rats. Am J Physiol 1987;253:G241-5.
15. Lenz HJ, Raedler A, Grenten H, Vale WW, Rivier JE. Stress-induced gastrointestinal secretory and motor responses in rats are mediated by endogenous corticotropin-releasing factor. Gastroenterology 1988;95:1510-7.
16. Gisslinger H, Svoboda T, Clodi M, Gilly B, Ludwig H, Havelec L, et al. Interferon-alpha stimulates the hypothalamic-pituitary-adrenal axis in vivo and in vitro. Neuroendocrinology 1993; 53:489-95.
17. Fitzgerald-Bocarsly P. Human natural interferon-α producing cells. Pharmacol Ther 1993;60:39-62.
18. Kim T, Kanayama Y, Negoro N, Okamura M, Takeda T, Inoue T. Serum levels of interferons in patients with systemic lupus erythematosus. Clin Exp Immunol 1987;70:562-9.
19. Brockmeyers NH, Mertins L, Spatz D, Tillmann I, Goos M. Endogenous interferon plasma levels and antipyrine pharmacokinetics in patients with viral infections. Int J Clin Pharmacol Ther Toxicol 1992;30:530-3.