The molecular behaviour of cetirizine

Clinical and Experimental Allergy, Supplement

Volumn 27, Issue 2, 1997, Pages 13-18

  Testa, B ^a   Pagliara, A ^a   Carrupt, P A ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CETIRIZINE;

CONFERENCE PAPER; CONFORMATIONAL TRANSITION; DRUG CONFORMATION; DRUG SOLUBILITY; LIPID SOLUBILITY; MATHEMATICAL ANALYSIS; MATHEMATICAL MODEL; PH; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

CETIRIZINE; HISTAMINE H1 ANTAGONISTS; HUMANS; LIPID METABOLISM;

EID: 0030834508     PISSN: 09602178     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (9)

1. 1-receptor antagonists in allergic disease. New York: Marcel Dekker, 1996:91-116.
2. van de Waterbeemd, Testa B. The parametrization of lipophilicity and other structural properties in drug design. In (B Testa ed). Advances in Drug Research. 16, Academic Press, London 1987: 87-227.
3. El Tayar N, Testa B, Carrupt PA. Polar intermolecular interactions encoded in partition coefficients: an indirect estimation of hydrogen bond parameters of polyfunctional solutes. J Phys Chem 1992; 96:1455-9.
4. Testa B, Carrupt PA, Gaillard P, Tsai RS. Intramolecular interactions encoded in lipophilicity: their nature and significance In: (V Pliska, B Testa, H van der Waterbeemd eds) Lipophilicity in Drug Action and Toxicology. VCH Publishers, Weinheim, 1996: 49-71.
5. Spencer CM, Faulds D, Peters DH. Cetirizine. A reappraisal of its pharmacological properties and therapeutic use in selected allergic disorders. Drugs 1993; 46:1055-80.
6. Simons FER, Walsh GM (eds). New criteria for classification of H1 blockers. Allergy 1995: 50(24).
7. Testa B, Carrupt PA, Gaillard P, Billois F, Weber P. Lipophilicity in molecular modelling. Pharmaceut Res 1996; 13:335-42.
8. Kantar A, Oggiano N, Gioirgi PL, J-P Rihoux. A study of the interaction between cetirizine and plasma membrane of eosinophils, neutrophils, platelets and lymphocytes using a fluorescence technique. Mediators Inflammation 1994; 3:229-43.
9. 1) antagonists. Allergy 1995; 50:12-6.