Effects of dexamethasone and phorbol ester on P2 receptor-coupled Ca2+ signalling and lipocortin 1 presentation in U937 cells

British Journal of Pharmacology

Volumn 122, Issue 6, 1997, Pages 1055-1060

  Willmott, Nicholas J ^a,b   Choudhury, Qam ^a   Flower, Roderick J ^a  

^a ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

^b Norvartis Inst for Medical Sciences   (United Kingdom)

Author keywords

ATP; Dexamethasone; Lipocortin 1; P2 receptors; Store operated calcium influx; U937 cells

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM ION; DEXAMETHASONE; DEXAMETHASONE SODIUM PHOSPHATE; LIPOCORTIN 1; MEMBRANE ANTIGEN; PHORBOL ESTER; PURINE P2 RECEPTOR; THAPSIGARGIN;

ARTICLE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CALCIUM TRANSPORT; CELL DIFFERENTIATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION;

ADENOSINE TRIPHOSPHATE; ANNEXIN A1; CALCIUM; CELL LINE; CELL MEMBRANE; DEXAMETHASONE; ION TRANSPORT; RECEPTORS, PURINERGIC P2; SIGNAL TRANSDUCTION; TETRADECANOYLPHORBOL ACETATE; THAPSIGARGIN;

EID: 0030834430     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701490     Document Type: Article

References (22)

1. BARICORDI, O.R., FERRARI, D., MELCHIORRI, L., CHIOZZ, P., HANAN, S., CHIARI, E., RUBINI, M. & DI-VIRIGLIO, F. (1996). An ATP-activated channel is involved in mitogenic stimulation of human T lymphocytes. Blood, 87, 682-690.
2. BARNARD, E.A., BURNSTOCK, G. & WEBB, T.E. (1994). G protein-coupled receptors for ATP and other nucleotides: a new receptor family. Trends Pharmacol. Sci., 15, 67-70.
3. BAUS, E., ANDRIS, F., DUBOIS, P.M., URBAIN, J. & LEO, O. (1996). Dexamethasone inhibits the early steps of antigen receptor signaling in activated T lymphocytes. J. Immunol., 156, 4555-4561.
4. BECHERUCCI, C., PERRETTI, M., SOLITO, E., GALEOTTI, C.L. & PARENTE, L. (1993). Conceivable difference in the anti-inflammatory mechanisms of lipocortins 1 and 5. Med. Inflamm., 2, 109-113.
5. BERRIDGE, M.J. (1993). Inositol trisphosphate and calcium signalling. Nature, 361, 315-325.
6. BURGER, A., BERENDES, R., LIEMANN, S., BENZ, J., HOFMANN, A., GOTTIG, P., HUBER, R., GERKE, V., THIEL, C., ROMISCH, J. & WEBER, K. (1996). The crystal structure and ion channel activity of human annexin II, a peripheral membrane protein. J. Mol. Biol., 257, 839-847.
7. 2. J. Lipid Mediat. Cell Signal., 12, 83-117.
8. 2-purinoreceptors. Br. J. Cancer, 75, 34-39.
9. FLOWER, R.J. & ROTHWELL, N.J. (1994). Lipocortin 1: cellular mechanisms and functional relevance. Trends Pharmacol. Sci., 15, 71-76.
10. KHAN, A.A., SOLOSKI, M.J., SHARP, A.H., SCHILLING, G., SABATINI, D.M., LI, S., ROSS, C.A. & SNYDER, S.H. (1996). Lymphocyte apoptosis: mediation by increased type 3 inositol 1,4,5-trisphosphate receptor. Science, 273, 503-507.
11. 2+ entry pathway in human neutrophils. J. Biol. Chem., 268, 13055-13061.
12. MONTERO, M., GARCIA-SANCHO, J. & ALVAREZ, J. (1993b). Inhibition of the store-operated calcium entry pathway by chemotactic peptide and by phorbol ester develops gradually and independently along differentiation of HL60 cells. J. Biol. Chem., 268, 26911-26919.
13. PARTISETI, M., LE DEIST, F., HIVROZ, C., FISCHER, A., KORN, H. & CHOQUET, D. (1994). The calcium current activated by T cell receptor and store depletion in human lymphocytes is absent in a primary immunodeficiency. J. Biol. Chem., 269, 32327-32335.
14. PERRETTI, M., WHELLER, S.K., HARRIS, J.G. & FLOWER, R.J. (1996). Modulation of ICAM-1 levels on U-937 cells and mouse macrophages by interleukin-1b and dexamethasone. Biochem. Biophys. Res. Commun., 223, 112-117.
15. 2 to the nuclear envelope elicits topographically localized phospholipid hydrolysis. Biochem. J., 318, 797-803.
16. POENIE, M. (1990). Alteration of intracellular fura-2 fluorescence by viscosity: a simple correction. Cell Calcium, 11, 85-91.
17. SHIBATA, K., KITAYAMA, S., MORITA, K., SHIRAKAWA, M., OKAMATO, H. & DOHI, T. (1994). Regulation by protein kinase C of platelet-activating factor- and thapsigargin-induced calcium entry in rabbit neutrophils. Jpn J. Pharmacol., 66, 273-276.
18. SHIPSTON, M.J. & ANTONI, F.A. (1992). Early glucocorticoid induction of calmodulin and its suppression by corticotropin-releasing factor in pituitary corticotrope tumor (AtT20) cells. Biochem. Biophys. Res. Commun., 189, 1382-1388.
19. SOLITO, E., NUTI, S. & PARENTE, L. (1994). Dexamethasone-induced translocation of lipocortin (annexin) 1 to the cell membrane of U-937 cells. Br. J. Pharmacol., 112, 347-348.
20. TORNQUIST, K. (1993). Modulatory effect of protein kinase C on thapsigargin-induced calcium entry in thyroid FRTL-5 cells. Biochem. J., 290, 443-447.
21. 2+ influx of U937 cells. FEBS Lett., 394, 159-164.
22. YAMAGUCHI, K., HABARA, Y., WARASHIMA, A. & KANNO, T. (1993). Effects of corticosteroids on cytosolic free calcium concentration of the rat zona glomerulosa cell. Biol. Signals, 6, 352-358.