Radioiodinated methylene blue for melanoma targeting: Chemical characterisation and tumour selectivity of labelled components

Nuclear Medicine and Biology

Volumn 24, Issue 4, 1997, Pages 305-310

  Blower, Philip J ^a,b   Clark, Katherine ^c   Link, Eva M ^d  

^a Nuclear Medicine Department   (United Kingdom)

^b Canterbury Hospital   (United Kingdom)

^c UNIVERSITY OF KENT   (United Kingdom)

^d ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

Melanoma; Methylene blue; Radioiodine

Indexed keywords

IODINE 131; METHYLENE BLUE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; INTRAVENOUS DRUG ADMINISTRATION; LIQUID SCINTILLATION COUNTING; MELANOMA; MOUSE; NUDE MOUSE; TUMOR XENOGRAFT;

EID: 0030834206     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-8051(97)00040-1     Document Type: Article

References (7)

1. 123I-labelled methylene blue and toluidine blue: Potential new agents for parathyroid scintigraphy. Nucl. Med. Commun. 11, 413-420.
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4. 211At-methylene blue in targeted radiotherapy of disseminated melanoma. Pigment Cell Res. 7, 358-362.
5. Link E., Costa D. C., Lui D., Ell P. J., Blower P. J. and Spittle M. F. (1996) Targetting disseminated melanoma with radiolabelled methylene blue: Comparitive bio-distribution studies in man and animals. Acta Oncologica 35, 331-341.
6. Link E. M., Blower P. J., Costa D. C., Ell P. J., Lane D., and Spittle M. F. (1996) Diagnostic potential of radioiodinated methylene blue for early melanoma metastases. Lancet 343, 753.
7. Potts A. M. (1964). The reaction of uveal pigment in vitro with polycyclic compounds. Invest. Ophthalmol. 3, 405-416.