Pharmacologic profiles of KRH-594, a novel nonpeptide angiotensin II- receptor antagonist

Journal of Cardiovascular Pharmacology

Volumn 30, Issue 5, 1997, Pages 607-615

  Tamura, K ^a   Okuhira, M ^a   Amano, H ^a   Inokuma, K I ^a   Hirata, T ^a   Mikoshiba, I ^a   Hashimoto, K ^a  

^a WAKUNAGA PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Acyliminothiadiazoline derivative; Angiotensin II; Angiotensin II receptor antagonist; Antihypertensive agents; KRH 594; Renin angiotensin system

Indexed keywords

2 [[5 ETHYL 3 [2' (1H TETRAZOL 5YL)BIPHENYL 4 YL]METHYL 1,3,4 THIADIAZOLIN 2 YLIDENE]AMINOCARBONYL] 1 CYCLOPENTENECARBOXYLIC ACID; 2 [[5 ETHYL 3 [[2' (1H TETRAZOL 5 YL)BIPHENYL 4 YL]METHYL] 1,3,4 THIADIAZOLIN 2 YLIDENE]CARBAMOYL] 1 CYCLOPENTENECARBOXYLIC ACID; ANGIOTENSIN 2 RECEPTOR ANTAGONIST; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANIMAL TISSUE; ANTIHYPERTENSIVE THERAPY; ARTICLE; CATTLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG POTENCY; DRUG RECEPTOR BINDING; HYPERTENSION; NONHUMAN; PRIORITY JOURNAL; RABBIT; RAT; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SPONTANEOUSLY HYPERTENSIVE RAT;

ANGIOTENSIN II; ANIMALS; ANTIHYPERTENSIVE AGENTS; AORTA, THORACIC; BINDING, COMPETITIVE; BLOOD PRESSURE; CATTLE; CEREBELLUM; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; HYPERTENSION; LIVER; LOSARTAN; MALE; RABBITS; RADIOLIGAND ASSAY; RATS; RATS, INBRED SHR; RATS, SPRAGUE-DAWLEY; RECEPTORS, ANGIOTENSIN; TETRAZOLES; THIADIAZOLES;

EID: 0030833940     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-199711000-00011     Document Type: Article

References (42)