Immunological localization and tissue distribution of alkyldihydroxyacetonephosphate synthase and deficiency of the enzyme in peroxisomal disorders

European Journal of Biochemistry

Volumn 247, Issue 2, 1997, Pages 511-517

  De Vet, Edwin C J M ^a   Biermann, Jan ^a   Van Den Bosch, Henk ^a,b  

^a UTRECHT UNIVERSITY   (Netherlands)

^b Department Biochemistry of Lipids   (Netherlands)

Author keywords

Ether phospholipid; Glycerone phosphate synthase; Membrane association; Peroxisomal disorder; Peroxisome

Indexed keywords

SYNTHETASE;

AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; BRAIN; CHONDRODYSPLASIA PUNCTATA; CONTROLLED STUDY; DISORDERS OF PEROXISOMAL FUNCTIONS; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME DEFICIENCY; ESCHERICHIA COLI; GENE EXPRESSION; GUINEA PIG; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; KIDNEY; LIVER; LUNG; MOLECULAR CLONING; MOLECULAR WEIGHT; NONHUMAN; PHOSPHOLIPID SYNTHESIS; PRIORITY JOURNAL; SPLEEN; TISSUE DISTRIBUTION; ZELLWEGER SYNDROME;

ANIMALIA; CAVIA PORCELLUS; ESCHERICHIA COLI; SUS SCROFA;

EID: 0030833862     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1432-1033.1997.00511.x     Document Type: Article

References (34)

1. Hanahan, D. J. (1986) Platelet activating factor: a biologically active phosphoglyceride, Annu. Rev. Biochem. 55, 483-509.
2. Hajra, A. K. & Bishop, J. E. (1982) Glycerolipid biosynthesis in peroxisomes via the acyl dihydroxyacetone phosphate pathway, Ann. NY Acad. Sci. 386, 170-182.
3. Hajra, A. K. (1995) Glycerolipid biosynthesis in peroxisomes (microbodies). Prog. Lipid Res. 34, 343-364.
4. Zomer, A. W. M., Opperdoes, F. R. & van den Bosch, H. (1995) Alkyl dihydroxyacetone phosphate synthase in glycosomes of Trypanosoma brucei,. Biochim. Biophys. Acta 1257, 167-173.
5. Van den Bosch, H., Schutgens, R. B. H., Wanders, R. J. A. & Tager, J. M. (1992) Biochemistry of peroxisomes. Annu. Rev. Biochem. 61, 157-197.
6. Wanders, R. J. A., Barth, P. G., Schntgens, R. B. H. & Heymans, H. S. A. (1996) Peroxisomal disorders: post- and prenatal diagnosis based on a new classification with flowcharts. Int. Pediatr. 11, 203-214.
7. Zomer, A. W. M., de Weerd, W. F. C., Langeveld, J. & van den Bosch, H. (1993) Ether lipid synthesis: purification and identification of alkyl dihydroxyacetone phosphate synthase from guinea-pig liver, Biochim. Biophys. Acta 1170, 189-193.
8. Brown, A. J. & Snyder, F. (1982) Alkyldihydroxyacetone-P synthase. J. Biol. Chem. 257, 8835-8839.
9. Horie, S., Das, A. K. & Hajra, A. K. (1992) Alkyldihydroxyacetonephosphate synthase from guinea pig liver peroxisomes. Methods Enzymol. 209, 385-390.
10. Bishop, J. E., Salem, M. & Hajra, A. K. (1982) Topographical distribution of lipid biosynthetic enzymes on peroxisomes (microbodies). Ann. NY Acad. Sci. 386, 411-413.
11. Hardeman, H. & van den Bosch, H. (1988) Rat liver dihydroxyacetone-phosphate acyltransferase: enzyme characteristics and localization studies. Biochin. Biophys. Acta 963, 1-9.
12. De Vet, E. C. J. M., Zomer, A. W. M., Lahaut, G. J. H. T. J. & van den Bosch, H. (1997) Polymerase chain reaction-based cloning of alkyl-dihydroxyacetonephosphate synthase complementary DNA from guinea pig liver, J. Biol. Chem. 272, 798-803.
13. Swinkels, B. W., Gould, S. J., Bodnar, A. G., Rachubinski, R. A. & Subramani, S. (1991) A novel cleavable peroxisomal targeting signal at the amino-terminus of the rat 3-ketoaeyl-CoA thiolase, EMBO J. 10, 3255-3262.
14. Schrakamp, G., Schalkwijk, C. G., Schutgens, R. B. H., Wanders, R. J. A., Tager, J. M. & van den Bosch, H. (1988) Plasmalogen biosynthesis in peroxisomal disorders: fatty alcohol versus alkylglycerol precursors. J. Lipid Res. 29, 325-334.
15. Motley, A., Hettema, E., Distel, B. & Tabak, H. (1994) Differential protein import deficiencies in human peroxisome assembly disorders. J. Cell Biol. 125, 755-767.
16. Slawecki, M. L., Dodt, G., Steinberg, S., Moser, A. B., Moser, H. W. & Gould, S. J. (1995) Identification of three distinet peroxisomal protein import defects in patients with peroxisome biogenesis disorders. J. Cell Sci. 108, 1817-1829.
17. Hopp, T. P. & Woods, K. R. (1981) Prediction of protein antigenic determinants from amino acid sequences, Proc. Natl Acad. Sci. USA 78, 3824-3828.
18. Karplus, P. A. & Schulz, G. E. (1985) Prediction of chain flexibility in proteins. Naturwissenschaften 72, 212-213.
19. Chou, P. Y. & Fasman, G. D. (1979) Prediction of β-turns, Biophys. J. 26, 367-384.
20. Harlow, E. & Lane, D. (1988) Antibodies: a laboratory manual, Cold Spring Harbor Laboratory Press, Cold Spring Harbor NY.
21. Fujiki, Y., Fowler, S., Shio, H., Hubbard, A. L. & Lazarow, P. B. (1982) Polypeptide and phospholipid composition of the membrane of rat liver peroxisomes: comparison with endoplasmic reticulum and mitochondrial membranes. J. Cell Biol. 93, 103-110.
22. Lipmann, F. & Tuttle, L. C. (1945) A specific micromethod for the determination of acyl phosphates. J. Biol. Chem. 159, 21-28.
23. Laemmli, U. K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4, Nature 227, 680-685.
24. Auffray, C. & Rougeon, F. (1980) Purification of mouse immunoglobulin heavy-chain messenger RNAs from total myeloma tumor RNA, Eur. J. Biochem. 107, 303-314.
25. Bradford, M. M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254.
26. Kyte, J. & Doolittle, R. F. (1982) A simple method for displaying the hydropathic character of a protein. J. Mol. Biol. 157, 105-132.
27. Schrakamp, G., Roosenboom, C. F. P., Schutgens, R. B. H., Wanders. R. J. A., Heymans, H. S. A., Tager, J. M. & van den Bosch, H. (1985) Alkyl dihydroxyacetone phosphate synthase in human fibroblasts and its deficiency in Zellweger syndrome, J. Lipid Res. 26, 867-873.
28. Hardeman, D., Versantvoort, C., van den Brink, J. M. & van den Bosch, H. (1990) Studies on peroxisomal membranes, Biochim. Biophys. Acta 1027, 149-154.
29. Bordier, C. (1981) Phase separation of integral membrane proteins in Triton X-114 solution, J. Biol. Chem. 256, 1604-1607.
30. Singh, H., Beckman, K. & Poulos, A. (1996) Evidence ot two catalytically active carnitine medium/long chain acyltransferases in rat liver peroxisomes. J. Lipid Res. 37, 2616-2626.
31. De Hoop, M. & Ab, G. (1992) Import of proteins into peroxisomes and other microbodies, Biochem. J. 286, 657-669.
32. De Vet, E. C. J. M., van den Broek, B. T. E. & van den Bosch, H. (1997) Nucleotide sequence of human alkyl-dihydroxyacetonephosphate synthase cDNA reveals the presence of a presequence containing the peroxisomal targeting signal 2, Biochim. Biophys. Acta 1346, 25-29.
33. Schram, A. W., Strijland, A., Hashimoto, T., Wanders, R. J. A., Schutgens, R. B. H., van den Bosch, H. & Tager, J. M. (1986) Biosynthesis and maturation of peroxisomal β-oxidation enzymes in fibroblasts in relation to the Zellweger syndrome and infantile Refsum disease, Proc. Natl Acad. Sci. USA 83, 6156-6158.
34. Lazarow, P. B. & Moser, H. W. (1989) Disorders in peroxisome biogenesis, in The metabolic basis of inherited disease (Scriver, C. R., Beaudet, A. L., Sly, W. S. & Valle, D., eds) pp. 1479-1509. McGraw-Hill, New York.