Exposure of laboratory animal workers to airborne rat and mouse urinary allergens

Clinical and Experimental Allergy

Volumn 27, Issue 6, 1997, Pages 617-626

  Hollander, A ^a   Van Run, P ^a   Spithoven, J ^a   Heederik, D ^a   Doekes, G ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

Aeroallergens; Exposure; Job title; Mouse; Rat; Task

Indexed keywords

ALLERGEN; IMMUNOGLOBULIN E;

AIRBORNE PARTICLE; ANTIBODY TITER; ARTICLE; DUST EXPOSURE; HUMAN; LABORATORY PERSONNEL; MOUSE; OCCUPATIONAL ALLERGY; OCCUPATIONAL EXPOSURE; PRIORITY JOURNAL; RAT; RISK ASSESSMENT;

ALLERGENS; ANIMALS; ANIMALS, LABORATORY; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FEMALE; HUMANS; IMMUNOENZYME TECHNIQUES; LABORATORY ANIMAL SCIENCE; MALE; MICE; MICE, INBRED BALB C; OCCUPATIONAL EXPOSURE; RABBITS; RATS; RATS, WISTAR; RESPIRATORY HYPERSENSITIVITY;

EID: 0030833805     PISSN: 09547894     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2222.1997.tb01188.x     Document Type: Article

References (36)

1. Gross NJ. Allergy to laboratory animals: epidemiologic, clinical, physiologic aspects, and a trial of cromolyn in its management. J Allergy Clin Immunol 1980; 22:158-65.
2. Slovak AJM, Hill RN. Laboratory animal allergy: a clinical survey of an exposed population. Br J Ind Med 1981; 38:38-41.
3. Schumacher MJ, Tait BD, Holmes MC. Allergy to murine antigens in a biological research institute. J Allergy Clin Immunol 1981; 68:310-8.
4. Cockcroft A, Edwards J, McCarthy P, Andersson N. Allergy in laboratory animal workers. Lancet 1981; 827-30.
5. Beeson MF, Dewdney JM, Edwards RG, Lee D, Orr RG. Prevalence and diagnosis of laboratory animal allergy. Clin Allergy 1983; 13:433-42.
6. Bland SM, Levine MS, Wilson PD, Fox NL, Rivera JC. Occupational allergy to laboratory animals: an epidemiological study. J Occup Med 1986; 28:1151-7.
7. Agrup G, Belin L, Sjöstedt L, Skerfving S. Allergy to laboratory animals in laboratory technicians and animal keepers. Br J Ind Med 1986; 43:192-8.
8. Botham PA, Davies GE, Teasdale EL. Allergy to laboratory animals: a prospective study of its incidence and of the influence of atopy on its development. Br J Ind Med 1987; 44:627-32.
9. Venables KM, Tee RD, Hawkins ER et al. Laboratory animal allergy in a pharmaceutical company. Br J Ind Med 1988; 45:660-6.
10. Kibby T, Powell G, Cromer J. Allergy to laboratory animals: a prospective and cross-sectional study. J Occup Med 1989; 31:842-6.
11. Aoyama K, Ueda A, Manda F et al. Allergy to laboratory animals: an epidemiological study. Br J Ind Med 1992; 49:41-7.
12. Cullinan P, Lowson D, Nieuwenhuijsen MJ et al. Work related symptoms, sensitisation, and estimated exposure in workers not previously exposed to laboratory rats. Occup Environ Med 1994; 51:589-2.
13. Davies GE, Thompson AV, Rackham M. Estimation of airborne rat-derived antigens by ELISA. J Immunoassay 1983; 4:113-26.
14. Corn M, Koegel A, Hall T, Scott A, Newill C, Evans R. Characteristics of airborne particles associated with animal allergy in laboratory workers. Ann Occup Hyg 1988; 32 supplement 1:435-46.
15. Lewis DM, Bledsoe TA, Dement JM. Laboratory animal allergies. Use of the radioallergosorbent test inhibition assay to monitor airborne allergen levels. Scand J Work Environ Health 1988; 14 supplement 1:74-6.
16. Price JA, Longbottom JL. ELISA method for measurement of airborne levels of major laboratory animal allergens. Clin Allergy 1988; 18:95-107.
17. Eggleston PA, Newill CA, Ansari AA et al. Task-related variation in airborne concentrations of laboratory animal allergens: Studies with RAT n I. J Allergy Clin Immunol 1989; 84:347-52.
18. Gordon S, Tee RD, Nieuwenhuijsen MJ, Lowson D, Harris J, Newman Taylor AJ. Measurement of airborne rat urinary allergen in an epidemiological study. Clin Exp Allergy 1994; 24:1070-7.
19. Zoek J, Hollander A, Doekes G, Heederik D. The influence of different filter elution methods on the measurement of airborne potato antigens. Am Ind Hyg Assoc J (in press).
20. Gordon S, Tee RD, Newman Taylor AJ. Analysis of rat urine proteins and allergens by sodium dodecyl sulfatepolyacrylamide gel electrophoresis and immunoblotting. J Allergy Clin Immunol 1993; 92:298-305.
21. Smith PK, Krohn RI, Hermanson GT, Mallia AK, Gartner FH, Provenzano MD, Fujimoto EK, Goeke NM, Olson BJ, Klenk DC. Measurement of protein using bicinochoninic acid. Annal Biochem 1985; 150:76-85.
22. Hollander A, Doekes G, Heederik D. Cat and dog allergy and total IgE as risk factors of laboratory animal allergy. J Allergy Clin Immunol 1996; 98:545-54.
23. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970; 227:680-5.
24. Boleij J, Buringh E, Heederik D. and Kromhout H. Occupational hygiene of chemical and biological agents. Amsterdam: Elsevier, 1995.
25. Newman Taylor A, Longbottom JL, Pepys J. Respiratory allergy to urine proteins of rats and mice. Lancet 1997; 847-9.
26. Schumacher MJ. Characterization of allergens from urine and pelts of laboratory mice. Mol Immunol 1980; 17:1087-95.
27. Walls AF, Longbottom JL. Comparison of rat fur, urine, saliva, and other rat allergen extracts by skin testing, RAST, and RAST inhibition. J Allergy Clin Immunol 1985; 75:242-51.
28. Lutsky I, Fink JN, Kidd J, Dahlberg MJE, Yuninger JW. Allergenic properties of rat urine and pelt extracts. J Allergy Clin Immunol 1985; 75:279-84.
29. Longbottom JL. Purification and characterization of allergens from the urines of mice and rats. Advances Allergy Clin Immunol 1979; 483-90.
30. Walls AF, Longbottom JL. Quantitative immunoelectrophoretic analysis of rat allergen extracts. II. Fur, urine and saliva studies by crossed radio-immunoelectrophoresis. Allergy 1983; 38:501-12.
31. Wahn U, Peters T, Siraganian RP. Studies of the allergenic significance and structure of rat serum albumin. J Immunol 1980; 125:2544-9.
32. Lorusso JR, Moffat S, Ohman JL. Immunologic and biochemical properties of the major mouse urinary allergen (Mus m I). J Allergy Clin Immunol 1986; 78:928-37.
33. Price JA, Longbottom JL. Allergy to mice. I. Identification of two major mouse allergens (Ag 1 and Ag 3) and investigation of their possible origin. Clin Allergy 1987; 17:43-53.
34. Price JA, Longbottom JL. Allergy to mice. II. Further characterization of two major mouse allergens (AG1 and AG3) and immunohistochemical investigations of their sources. Clin Exp Allergy 1990; 20:71-7.
35. Renström A, Gordon S, Larsson PH, Tee RD, Newman Taylor AJ, Malmberg P. Comparison of a monoclonal ELISA and a RAST inhibition method for aeroallergen measurement. Annual meeting EAACI Stockholm, Sweden 1994;456. (Abstract).
36. Nieuwenhuijsen MJ, Gordon S, Tee RD, Venables KM, McDonald JC, Newman Taylor AJ. Exposure to dust and rat urinary aeroallergens in research establishments. Occup Environ Med 1994; 51:593-6.