Synthesis of dispacamide from the marine sponge Agelas dispar

Tetrahedron Letters

Volumn 38, Issue 52, 1997, Pages 8935-8938

  Lindel, Thomas ^a   Hoffmann, Holger ^a  

^a Pharmazeutisch Chemisches I der U   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALOID; AMMONIA; NATURAL PRODUCT; THIOHYDANTOIN DERIVATIVE;

ARTICLE; CONTROLLED STUDY; DRUG SYNTHESIS; SPONGE;

AGELAS DISPAR;

EID: 0030833160     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(97)10387-2     Document Type: Article

References (16)

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3. Cafieri, F.; Fattorusso, E.; Mangoni, A.; Taglialatela-Scafati, O. Tetrahedron Lett. 1996, 37, 3587-3590. On the basis of recent NMR data on 2-aminoimidazolones, the exocyclic imino tautomer should be preferred: Talaty, E. R.; Yusoff, M. M.; Ismail, A.; Gomez, J. A.; Keller, C. E.; Younger, J. M. Synlett 1997, 683-684.
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14. 2 calcd. 405.9358, found 405.9370.
15. Photoisomerization of alkylidene aminoimidazolones has also been observed for marine indole alkaloids of the aplysinopsin class, see: Guella, G.; Mancini, I.; Zibrowius, H.; Pietra, F. Helv. Chim. Acta 1989, 72, 1444-1450.
16. Aminoiminomethanesulfinic and sulfonic acids react with amines to give the corresponding guanidines: Maryanoff, C. A.; Stanzione, R. C.; Plampin, J. N.; Mills, J. E. J. Org. Chem. 1986, 51, 1882-1884.