Lipophilic derivatization of the anti-viral drug 9-(2- phosphonylmethoxyethyl)adenine and its incorporation into a lactosylated lipid carrier to improve its liver uptake

Nucleosides and Nucleotides

Volumn 16, Issue 7-9, 1997, Pages 1279-1282

  De Vrueh, Remco L A ^a   Rump, Erik T ^a   Biessen, Erik A L ^a   Balzarini, Jan ^b   Van Berkel, Theo J C ^a   Bijsterbosch, Martin K ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

^b REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ADEFOVIR; ANTIVIRUS AGENT; ASIALOFETUIN; DRUG CARRIER; LIPID; LITHOCHOLIC ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; CONFERENCE PAPER; CONTROLLED STUDY; DOSE RESPONSE; DRUG CLEARANCE; DRUG FORMULATION; DRUG TISSUE LEVEL; DRUG UPTAKE; HEPATITIS B; HEPATITIS B VIRUS; INTRAVENOUS DRUG ADMINISTRATION; LIPOPHILICITY; LIVER CELL; MALE; NEPHROTOXICITY; NONHUMAN; RAT; VIRUS REPLICATION;

ANIMALIA; HEPATITIS B VIRUS;

EID: 0030833037     PISSN: 07328311     EISSN: None     Source Type: Journal    
DOI: 10.1080/07328319708006170     Document Type: Conference Paper

References (9)

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