Effect of melatonin and pineal peptide preparation epithalamin on life span and free radical oxidation in Drosophila melanogaster

Mechanisms of Ageing and Development

Volumn 97, Issue 2, 1997, Pages 81-91

  Anisimov, Vladimir N ^a   Mylnikov, Sergey V ^b   Oparina, Tatyana I ^b   Khavinson, Vladimir Kh ^c  

^a N N PETROV RESEARCH INSTITUTE OF ONCOLOGY   (Russian Federation)

^b ST PETERSBURG STATE UNIVERSITY   (Russian Federation)

^c St Petersburg Institute of Bioregulation and Gerontology   (Russian Federation)

Author keywords

Drosophila melanogaster; Epithalamin; Free radical oxidation; Life span; Melatonin

Indexed keywords

ANTIOXIDANT; CATALASE; COPPER ZINC SUPEROXIDE DISMUTASE; EPITHALAMIN; FREE RADICAL; HYDROPEROXIDE; MELATONIN;

AGING; ANTIOXIDANT ACTIVITY; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME ACTIVITY; FEMALE; GENITAL SYSTEM; HORMONE RELEASE; HORMONE SYNTHESIS; IMMUNE SYSTEM; LIFESPAN; LIPID PEROXIDATION; MALE; MORTALITY; NONHUMAN; OXIDATION; PRIORITY JOURNAL; SEX DIFFERENCE; SURVIVAL;

ANIMALS; CATALASE; DROSOPHILA MELANOGASTER; FEMALE; FREE RADICALS; LIPID PEROXIDATION; LONGEVITY; MALE; MELATONIN; OXIDATION-REDUCTION; PEPTIDES; PINEAL GLAND; SUPEROXIDE DISMUTASE;

CHANDIPURA VIRUS; DROSOPHILA MELANOGASTER; MELANOGASTER;

EID: 0030832307     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0047-6374(97)01897-6     Document Type: Article

References (34)

1. D. Harman, Free-radical theory of aging: increasing the functional life span. Ann. N. Y. Acad. Sci., 717 (1994) 1-15.
2. M.K. Shigenaga, T.M. Hogen and B.N. Ames, Oxidative damage and mitochondrial decay in aging. Proc. Natl Acad. Sci. USA, 91 (1994) 10771-10778.
3. G.M. Martin, S.N. Austad and T.E. Johnson, Genetic analysis of aging: role of oxidative damage and environmental stresses. Nat. Genet., 13 (1996) 25-34.
4. N.M. Emanuel and L.K. Obukhova, Types of experimental delay in aging patterns. Exp. Gerontol., 13 (1978) 25-29.
5. S.P. Sharma and R. Wadha, Effect of butylated hydroxytoluene on the life span of Drosophila bipenctinata. Mech. Aging Dev., 23 (1983) 67-71.
6. W.C. Orr and R.S. Sohal, Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster. Science, 263 (1994) 1128-1130.
7. B. Poeggeler, R.J. Reiter, D.-X. Tan, Chen L.-D. and L.C. Manchester, Melatonin hydroxyl radical-mediated oxidative damage, and aging: a hypothesis. J. Pineal Res., 14 (1993) 151-168.
8. R.J. Reiter, The pineal gland and melatonin in relation to aging: a summary of the theories and of the data. Exp. Gerontol., 30 (1995) 199-212.
9. R.J. Reiter, D. Melchiorri, M.D. Sewerinek et al., A review of the evidence supporting melatonin's role as an antioxidant. J. Pineal Res., 18 (1995) 1-11.
10. E. Sewerynek, M. Abe, R.J. Reiter et al., Melatonin administration prevents lipopolysaccharide-in-duced oxidative damage in phenobarbital-treated animals. J. Cell. Biochem., 58 (1995) 436-444.
11. W. Pierpaoli and W. Regelson, Pineal control of aging: effect of melatonin and pineal grafting on aging mice. Proc. Natl. Acad. Sci. USA, 91 (1994) 787-791.
12. S. Oakin-Bendahan, Y. Anis, I. Nir and N. Zisappel, Effects of long-term administration of melatonin and a putative antagonist on the ageing rat. Neuroreport, 6 (1995) 85-788.
13. S.M. Reppert and D.R. Weaver, Melatonin madness. Cell, 83 (1995) 1059-1062.
14. F.W. Turek, Melatonin hipe hard to swallow. Nature, 379 (1996) 295-296.
15. D. Bonn, Melatonin's multifarious marvels: miracle or myth? Lancet, 347 (1996) 184.
16. V.N. Anisimov, V.Kh. Khavinson and V.G. Morozov, Carcinogenesis and aging. IV. Effect of low molecular-weight factors of thymus, pineal gland and anterior hypothalamus on immunity, tumor incidence and life span of C3H/Sn mice. Mech. Ageing Dev., 19 (1982) 245-258.
17. V.N. Anisimov, V.Kh. Khavinson and V.G. Morozov, Twenty years of study on effect of pineal peptide preparation: epithalamin in experimental gerontology and oncology. Ann. N. Y. Acad. Sci., 719 (1994) 483-493.
18. V.M. Dilman, V.N. Anisimov, M.N. Ostroumova, V.Kh. Khavinson and V.G. Morozov, Increase in life span of rats following polipeptide pineal extract treatment. Exp. Pathol., 17 (1979) 539-545.
19. V.N. Anisimov, A.S. Loktionov, V.Kh. Khavinson and V.G. Morozov, Effect of low molecular-weight factors of thymus and pineal gland on life span and spontaneous tumour development in female mice of different age. Mech. Ageing Dev., 49 (1989) 245-257.
20. V.N. Anisimov, L.A. Bondarenko and V.Kh. Khavinson, Effect of pineal peptide preparation (epithalamin) on life span and pineal and serum melatonin level in old rats. Ann. N. Y. Acad. Sci., 673 (1992) 53-57.
21. V.N. Anisimov, V.M. Prokopenko and V.Kh. Khavinson, Melatonin and epithalamin inhibit process of free radical oxidation in rats. Proc. Russian Acad. Sci., 343 (1995) 557-559.
22. V.N. Anisimov, A.V. Arutyunian and V.Kh. Khavinson, Melatonin and epithalamin inhibit process of lipid peroxidation in rats. Proc. Russian Acad.Sci., 348 (1996) 265-267.
23. V.N. Anisimov, A.V. Arutyunian and V.Kh. Khavinson, Effect of melatonin and epithalamin on activity of antioxidant defense system in rats. Proc. Russian Acad. Sci., 352 (1997) 831-833.
24. J. Arendt, Melatonin and the Mammalian Pineal Gland. Chapman Hall, London, 1995, p. 183.
25. B. Vivien-Roels and P. Pevet, Melatonin: presence and formation in invertebrates. Experientia, 49 (1993) 6420-647.
26. S.V. Mylnikov and A.N. Smirnova, Adult mortality in the inbred selected Drosophila melanogaster stocks and their hybrids. Ontogenez, 25 (4) (1994) 7-11.
27. L.K. Obukhova N.Sh. Nakaidze, A.M. Serebryany and L.D. Smirnov, Experimental analysis of the mechanismx of aging in Drosophila melanogaster. Exp. Gerontol., 14 (1979) 335-342.
28. T.F. Slater, Overview of methods used for detecting lipid peroxidation. Methods Enzymol., 195 (1994) 283-293.
29. A. Agostini, G.C. Gerli, L. Berletta and M. Bianchi, Superoxide dismutase, catalase and glutathione peroxidase activities in maternal and cord blood erythrocytes. J. Clin. Chem. Clin. Biochem., 18 (1980) 772-773.
30. E.V. Gubler, Calculating Methods of Analysis and Recognition of Pathological Processes. Meditsina, Leningrad, 1978.
31. C.E. Finch and L. Hayflick (eds), Handbook of the Biology of Aging. Van Nostrand Reinhold, New York, 1977.
32. S.V. Mylnikov, A.N. Smirnova and T.I. Oparina, Comparative genetic analysis of interlinear differences in the rate level of lipid peroxidation and longevity in Drosophila melanogaster. Genetika, 39 (1994) 1466-1466.
33. S. Agarwal and R.S. Sohal, DNA oxidative damage and life expectancy in houseflies. Proc. Natl. Acad. Sci. USA, 91 (1994) 12332-12335.
34. O.J. Malm, O.E. Skaug and P. Lingjaerde, The effect of pinealectomy on bobily growth, survival rate and 32p uptake in the rat. Acta Endocrinol., 30 (1959) 22-28.