Kinetic analysis of the disposition of MRK16, an anti-P-glycoprotein monoclonal antibody, in tumors: Comparison between in vitro and in vivo disposition

Journal of Pharmacology and Experimental Therapeutics

Volumn 283, Issue 1, 1997, Pages 391-401

  Mano, Yuji ^a   Suzuki, Hiroshi ^a   Terasaki, Tetuya ^a   Iwahashi, Toshiro ^b   Ono, Ken Ichi ^b   Naito, Mikihiko ^a   Tsuruo, Takashi ^a   Sugiyama, Yuichi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b SANOFI   (France)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN P; MONOCLONAL ANTIBODY; MRK 16; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG BINDING; DRUG BLOOD LEVEL; DRUG DISPOSITION; FEMALE; HUMAN; HUMAN CELL; INTRAVENOUS DRUG ADMINISTRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; STEADY STATE;

ANIMALS; ANTIBODIES, MONOCLONAL; COLORECTAL NEOPLASMS; FEMALE; HUMANS; MICE; MICE, INBRED BALB C; MICE, NUDE; P-GLYCOPROTEIN; SENSITIVITY AND SPECIFICITY; TUMOR CELLS, CULTURED;

EID: 0030831950     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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