Safety and efficacy of oral flecainide acetate in patients with cardiac arrhythmias

Japanese Heart Journal

Volumn 38, Issue 3, 1997, Pages 379-385

  Nakazato, Yuji ^a   Nakata, Yasuro ^a   Yasuda, Masayuki ^a   Nakazato, Kaoru ^a   Sumiyoshi, Masataka ^a   Ogura, Shunsuke ^a   Yamaguchi, Hiroshi ^a  

^a JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Flecainide; Proarrhythmia; ST elevation

Indexed keywords

ANTIARRHYTHMIC AGENT; FLECAINIDE ACETATE;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG SAFETY; FEMALE; HEART ARRHYTHMIA; HEART ATRIUM CONTRACTION; HEART ATRIUM FIBRILLATION; HEART ATRIUM FLUTTER; HEART VENTRICLE CONTRACTION; HEART VENTRICLE TACHYCARDIA; HUMAN; MALE; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RETROSPECTIVE STUDY; ST SEGMENT ELEVATION; SUPRAVENTRICULAR TACHYCARDIA;

EID: 0030831277     PISSN: 00214868     EISSN: None     Source Type: Journal    
DOI: 10.1536/ihj.38.379     Document Type: Article

References (16)

1. Prichett ELC, DaTorre SD, Platt ML, McCarville SE, Hougham AJ and The Flecainide Supraventricular Tachycardia Study Group. Flecainide acetate treatment of paroxysmal supra ventricular tachycardia and paroxysmal atrial fibrillation: dose-response studies. J Am Coll Cardiol 1991; 17: 297-303.
2. Wiseman MN, Elstob JE, Camm AJ, Nathan AW. A study of the use of flecainide acetate in the long-term management of cardiac arrhythmias. Pacing Clin Electrophysiol 1990; 13: 767-75.
3. Neuss H, Schlepper M. Long-term efficacy and safety of flecainide for Supraventricular tachycardia. Am J Cardiol 1988; 62: 56D-61D.
4. Facchini M, Varisco T, Bonazzi O, Priori SG, Songa V, Schwanz PJ. Efficacy and safety of flecainide in low-risk patients with chronic ventricular arrhythmias: a two-year follow-up. Am Heart J 1989; 117: 1258-64.
5. CAST Investigators. Preliminary report: effect of encainide and flecainide on mortality in a randomized trial of arrhythmia suppression after myocardial infarction. N Engl J Med 1989; 321: 406-12.
6. Pietersen AH, Hellemann H, The Danish-Norwegian Flecainide Multicenter Study Group. Usefulness of flecainide for prevention of paroxysmal atrial fibrillation and flutter. Am J Cardiol 1991; 67: 713-7.
7. Sihm I, Rasmussen HJ, Pedersen AK, Thygesen K. Flecainide acetate in atrial flutter and fibrillation. Eur Heart J 1990; 11: 145-8.
8. Hohnloser SH, Zabel M. Short- and long-term efficacy and safety of flecainide acetate for Supraventricular arrhythmias. Am J Cardiol 1992; 70: 3A-10A.
9. Brembilla-Perrot B, Amor M, Auque F, et al. Effect of flecainide on left ventricular ejection fraction. Eur Heart J 1987; 8: 754-81.
10. Feld GK, Chen PS, Nicod P, Fleck RP, Meyer D. Possible atrial proarrhythrnic effects of class le antiarrhythmic drugs. Am J Cardiol 1990; 66: 378-83.
11. Berns E, Rinkenberger RL, Keang MK, Dougherry AH, Jenkins M, Naccarelli GV. Efficacy and safety of flecainide acetate for atrial tachycardia or fibrillation. Am J Cardiol 1987; 59: 1337-41.
12. Brugada P, Brugada J. Right bundle branch block, persistent ST segment elevation and sudden cardiac death: a distinct clinical and electrocardiographic syndrome. A multicenter report. J Am Coll Cardiol 1992; 62: 1303-6.
13. Nakazato Y, Nakata Y, Aihara K, et al. The anti- and pro-arrhythmic effects of flecainide during the treatment for paroxysmal atrial flutter and fibrillation. Ther Res 1996; 17: 311-5. (in Japanese)
14. Crijns HJ, Gelder IC, Lie KI. Supraventricular tachycardia mimicking ventricular tachycardia during flecainide treatment. Am J Cardiol 1986; 62: 1303-6.
15. Aubel KJJCM, Ruiter JH, Arnold AER, Burgersdijk C. Pseudo infarction EGG pattern occurring during intravenous treatment with flecainide acetate. Eur Heart J 1992; 13: 137-9.
16. Miyazaki T, Mhamura H, Miyoshi S, Soejima K, Aizawa Y, Ogawa S. Autonomic and antiarrhythmic drug modulation of ST segment elevation in patients with Brugada syndrome. J Am Coll Cardiol 1996; 27: 1061-70.