PTHrP and cell division: Expression and localization of PTHrP in a keratinocyte cell line (HaCaT) during the cell cycle

Journal of Cellular Physiology

Volumn 173, Issue 3, 1997, Pages 433-446

  Lam, M H C ^a   Olsen, S L ^a   Rankin, W A ^a   Ho, P W M ^a   Martin, T J ^a   Gillespie, M T ^a   Moseley, J M ^a,b  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b ST VINCENT'S INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

PARATHYROID HORMONE RELATED PROTEIN;

ARTICLE; CANCER CELL CULTURE; CELL CULTURE; CELL CYCLE; CELL DIVISION; CELL SYNCHRONIZATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; KERATINOCYTE; PRIORITY JOURNAL;

APHIDICOLIN; CELL CYCLE; CELL DIVISION; CELL LINE; CYCLIN D1; CYCLIN E; DEMECOLCINE; HUMANS; KERATINOCYTES; KINETICS; PARATHYROID HORMONE; PARATHYROID HORMONE-RELATED PROTEIN; PROTEIN BIOSYNTHESIS; PROTEINS; RNA, MESSENGER; TIME FACTORS; TRANSCRIPTION, GENETIC;

EID: 0030830560     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4652(199712)173:3<433::AID-JCP16>3.0.CO;2-C     Document Type: Article

References (50)

1. Allinson, E.T., and Drucker, D.J. (1992) Parathyroid hormone-like peptide shares features with members of the early response gene family: Rapid induction by serum, growth factors, and cycloheximide. Cancer Res., 52:3103-3109.
2. Amizuka, N., Warshawsky, H., Henderson, J.E., Goltzman, D., and Karaplis, A.C. (1994) Parathyroid hormone-related peptide-depleted mice show abnormal epiphyseal cartilage development and altered endochondral bone formation. J. Cell Biol., 126:1611-1623.
3. Amling, M., Neff, L., Tanaka, S., Inoue, D., Kuida, K., Weir, E., Philbrick, W.M., Broadus, A.E., and Baron, R. (1997) Bcl-2 lies downstream of parathyroid hormone-related peptide in a signaling pathway that regulates chondrocyte maturation during skeletal development. J. Cell Biol., 136:205-213.
4. Berridge, M.J. (1995) Calcium signaling and cell proliferation. Bioassays, 17:491-500.
5. Bizzarri, C., and Civitelli, R. (1994) Activation of the Ca2+ message system by parathyroid hormone is dependent on the cell cycle. Endocrinology, 134:133-140.
6. Boukamp, P., Petrussevska, R.V., Breitkreutz, D., Hornung, J., Markham, A., and Fusenig, N.E. (1988) Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line. J. Cell Biol., 106:761-771.
7. Breikreutz, D., Boukamp, P., Ryle, C.M., Stark, H.-J., Roop D.R., and Fusenig, N.E. (1991) Epidermal morphogenesis and keratin expression in c-Ha-ras-transfected tumoregenic clones of the human HaCaT cell line. Cancer Res., 51:4402-4409.
8. Campos, R.V., Asa, S.L., and Drucker, D.J. (1991) Immunocytochemical localization of parathyroid hormone-like peptide in the rat fetus. Cancer Res., 51:6351-6357.
9. Ciapa, B., Pesando, D., Wilding, M., and Whitaker, M. (1994) Cell-cycle calcium transients driven by cyclic changes in inositol triphosphate changes. Nature, 368:875-878.
10. Dugaiczyk, A., Harm, J.A., Stone, E.M., Dennison, D.E., and Rothblum, K.N. (1983) Cloning and sequencing of a deoxyribonucleic acid copy of glyceraldehyde-3-phosphate dehydrogenase messenger ribonucleic acid isolated from chicken muscle. Biochemistry, 22:1605-1613.
11. Dunne, F.P., Ratcliffe, W.A., Mansour, P., and Heath, D.A. (1994) Parathyroid hormone related protein (PTHrP) gene expression in fetal and extra-embryonic tissues of early pregnancy. Hum. Reprod., 9:149-156.
12. Fuller, P.J., Matheson, B.A., MacDonald, R.J., Verity, K., and Clenents, J.A. (1988) Kallikrein gene expression in estrogen-induced pituitary tumors. Mol. Cell. Endocrinol., 60:225-232.
13. Goltzman, D., Henderson, J.E., Kaiser, S., Kremer, R., Rabbani, S.A., and Hendy, G.N. (1992) Studies of the molecular biology of parathyroid hormone-like peptide. J. Endocrinol. Invest., 15:43-49.
14. Grill, V., Ho, P., Body, J.J., Johanson, N., Lee, S.C., Kukreja, S.C., Moseley, J.M., and Martin, T.J. (1991) Parathyroid hormone-related protein: Elevated levels in both humoral hypercalcemia of malignancy and hypercalcemia complicating metastatic breast cancer. J. Clin. Endocrinol. Metab., 73:1309-1315.
15. Hanafin, N.M., Chen, T.C., Hendy, G., Segre, G.V., and Holick, M.F. (1995) Cultured human fibroblasts and not cultured human keratinocytes express a PTH/PTHrP receptor mRNA. J. Invest. Dermatol., 105:133-137.
16. Hayman, J.A., Danks, J.A., Ebeling, P.R., Moseley, J.M., Kemp, B.E., and Martin, T.J. (1989) Expression of parathyroid hormone-related protein in normal skin and in tumors of skin and appendages. J. Pathol., 158:293-296.
17. Heath, J.K., Southby, J., Fukumoto, S., O'Keefe, L.M., Martin, T.J., and Gillespie, M.T. (1995) Epidermal growth factor-stimulated parathyroid hormone-related protein expression involves increased gene transcription and mRNA stability. Biochem. J., 307:159-167.
18. Heichman, K.A., and Roberts, J.M. (1994) Rules to replicate by. Cell, 79:557-562.
19. Henderson, J.E., Sebag, M., Rhim, J., Goltzman, D., and Kremer, R. (1991) Dysregulation of parathyroid hormone-like peptide expression and secretion in a keratinocyte model of tumor progression. Cancer Res., 51:6521-6528.
20. Henderson, J.E., Amizuka, N., Warshawsky, H., Biasotto, D., Lanske, B.M.K., Goltzman, D., and Karaplis, A.C. (1995) Nucleolar localization of parathyroid hormone-related peptide enhances survival of chrondrocytes under conditions that promote apoptotic cell death. Mol. Cell. Biol., 15:4064-4075.
21. Holick, M.F., Ray, S., Chen, T.C., Tian, X., and Persons, K.S. (1994) A parathyroid hormone antagonist stimulates epidermal proliferation and hair growth in mice. Proc. Natl. Acad. Sci. U.S.A., 91:8014-8016.
22. 124 inhibits nuclear import of SV-40 T antigen proteins. J. Cell Biol., 115:1203-1212.
23. Kaiser, S.M., Laneuville, P., Bernier, S.M., Rhim, J.S., Kremer, R., and Goltzman, D. (1992) Enhanced growth of a human keratinocyte cell line induced by antisense RNA for parathyroid hormone-related peptide. J. Biol. Chem., 267:13623-13628.
24. Kaiser, S.M., Sebag, M., Rhim, J.S., Kremer, R., and Goltzman, D. (1994) Antisense-mediated inhibition of parathyroid hormone-related peptide production in a keratinocyte cell line impedes differentiation. Mol. Endocrinol., 8:139-147.
25. Karaplis, A.C., Luz, A., Glowacki, J., Bronson, R.T., Tybulewicz, V.L.J., Kronenberg, H.M., and Mulligan, R.C. (1994) Lethal skeletal dysplasia from targeted disruption of the parathyroid hormone-related peptide gene. Genes Dev., 8:277-289.
26. Karperien, M., Van Dijk, T.B., Hoeijmakers, T., Cremers, F., Abou Samra, A.B., Boonstra, J., DeLaat, S.W., and Defize, L.H.K. (1994) Expression pattern of parathyroid hormone/parathyroid hormone-related protein receptor mRNA in mouse postimplantation embryos indicates involvement in multiple developmental processes. Mech. Develop., 47:29-42.
27. Kato, M., Ishizaki, A., Hellman, U., Wernstedt, C., Kyogaku, M., Miyazano, K., Heldin, C.-H., and Funa, K. (1995) A human keratinocyte cell line produces two autocrine growth inhibitors, transforming growth factor-β and insulin-like growth factor binding protein-6, in a calcium and cell density dependent manner. J. Biol. Chem., 270:12373-12379.
28. King, R.W., Jackson, P.K., and Kirschner, M.W. (1994) Mitosis in transition. Cell, 79:563-571.
29. Kiriyama, T., Gillespie, M.T., Glatz, J.A., Fukumoto, S., Moseley, J.M., and Martin, T.J. (1993) Transforming growth factor beta stimulation of parathyroid hormone-related protein (PTHrP): A paracrine regulator? [published erratum appears in Mol. Cell. Endocrinol., 1993, 94:145]. Mol. Cell. Endocrinol., 92:55-62.
30. Lee, K.C., Deeds, J.D., and Segre, G.V. (1995) Expression of parathyroid hormone-related peptide and its receptor messenger ribonucleic acids during fetal development of rats. Endocrinology, 136:453-463.
31. 3 on human keratinocytes grown under different culture conditions. In Vitro Cell. Dev. Biol., 26:379-387.
32. Means, A.R. (1994) Calcium, calmodulin and cell cycle regulation. FEBS Lett., 347:1-4.
33. Merryman, J.I., Capen, C.C., McCauley, L.K., Werkmeister, J.R., Suter, M.M., and Rosol, T.J. (1993) Regulation of parathyroid hormone-related protein production by a squamous carcinoma cell line in vitro. Lab. Invest., 69:347-354.
34. Merryman, J.I., DeWille, J.W., Werkmeister, J.R., Capen, C.C., and Rosol, T.J. (1994) Effects of transforming growth factor-beta on parathyroid hormone-related protein production and ribonucleic acid expression by a squamous carcinoma cell line in vitro. Endocrinology, 134:2424-2430.
35. Moseley, J.M., and Gillespie, M.T. (1995) Parathyroid hormone-related protein. Crit. Rev. Clin. Lab. Sci., 32:299-343.
36. Musgrove, E.A., Hamilton, J.A., Lee, C.S., Sweeney, K.J., Watts, C.K., and Sutherland, R.L. (1993) Growth factor, steroid, and steroid antagonist regulation of cyclin gene expression associated with changes in T-47D human breast cancer cell cycle progression. Mol. Cell. Biol., 13:3577-3587.
37. 1 to complete the cell cycle. Proc. Natl. Acad. Sci. U.S.A., 91:8022-8026.
38. 1 in mammalian fibroblasts. Science, 259:1908-1912.
39. Okano, K., Pirola, C.J., Wang, H.M., Forrester, J.S., Fagin, J.A., and Clemens, T.L. (1995) Involvement of cell cycle and mitogen-activated pathways in induction of parathyroid hormone-related protein gene expression in rat aortic smooth muscle cells. Endocrinology, 136:1782-1789.
40. 1 events and regulation of cell proliferation. Science, 246:603-608.
41. Philbrick, W.M., Wysolmerski, J.J., Galbraith, S., Holt, E., Orloff, J.J., Yang, K.H., Vasavada, R.C., Weir, E.C., Broadus, A.E., and Stewart, A.F. (1996) Defining the roles of parathyroid hormone-related protein in normal physiology. Physiol. Rev., 76:127-173.
42. Rankin, W., Murphy, B., Grill, V., Ho, P.W.M., Moseley, J.M., and Martin, T.J. (1995) Monoclonal antibody against parathyroid hormone-related protein with in vitro neutralizing activity. Bone, 16:2058.
43. Rosol, T.J., Grone, A., Weckmann, M.T., and Capen, C.C. (1995) Differential regulation of parathyroid hormone-related protein by keratinocytes in monolayer and organotypic cultures. Bone, 16:124S.
44. Ryle, C.M., Breikreutz, D., Stark, H.-J., Leigh, I.M., Steinert, P.M., Roop, D., and Fusenig, N.E. (1989) Density-dependant modulation of synthesis of keratins 1 and 10 in the human keratinocyte cell line HaCaT and in ras-transfected tumoregenic clones. Differentiation, 40:42-45.
45. Senior, P.V., Heath, D.A., and Beck, F. (1991) Expression of parathyroid hormone-related protein messenger RNA in the rat before birth: Demonstration by hybridization histochemistry. J. Mol. Endocrinol., 6:281-290.
46. Suva, L.J., Winslow, G.A., Wettenhall, R.E., Hammonds, R.G., Moseley, J.M., Rodda, C.P., Kemp, B.E., Rodriguez, H., Chen, E.Y., Hudson, P.J., Martin, T.J., and Wood, W.I. (1987) A parathyroid hormone-related protein implicated in malignant hypercalcemia: Cloning and expression. Science, 237:893-896.
47. Werkmeister, J.R., Merryman, J.I., McCauley, L.K., Horton, J.E., Capen, C.C., and Rosol, T.J. (1993a) Parathyroid hormone-related protein production by normal human keratinocytes in vitro. Exp. Cell Res., 208:68-74.
48. Werkmeister, J.R., Merryman, J.I., McCauley, L.K., Horton, J.E., Capen, C.C., and Rosol, T.J. (1993b) Parathyroid hormone-related protein (PTHrP) production in normal and malignant keratinocytes. J. Bone Miner. Res., 8 (suppl. 1):5200.
49. Wysolmerski, J.J., McCaughern-Carucci, J.F., Daifotis, A.G., and Broadus, A.E. (1995) Overexpression of parathyroid hormone-related protein in transgenic mice impairs branching morphogenisis during mammary gland development. Development, 121:3539-3547.
50. Zetterberg, A. (1990) Control of mammalian cell proliferation. Curr. Opin. Cell Biol., 2:296-300.