Calcineurin activity in children with renal transplants receiving cyclosporine

Transplantation

Volumn 64, Issue 10, 1997, Pages 1486-1489

  Quien, Ramcel M ^a   Kaiser, Bruce A ^a   Dunn, Stephen P ^a   Kulinsky, Anatoly ^a   Polinsky, Martin ^a   Baluarte, H J ^a   Batiuk, Thomas D ^b   Halloran, Philip F ^b  

^a ST CHRISTOPHER'S HOSPITAL FOR CHILDREN   (United States)

^b UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AZATHIOPRINE; CALCINEURIN; CYCLOSPORIN; PREDNISONE;

ADOLESCENT; ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG MECHANISM; HUMAN; KIDNEY FAILURE; KIDNEY GRAFT REJECTION; KIDNEY TRANSPLANTATION; ORAL DRUG ADMINISTRATION; PEDIATRIC SURGERY; PRIORITY JOURNAL; SCHOOL CHILD; T LYMPHOCYTE ACTIVATION;

EID: 0030830238     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199711270-00022     Document Type: Article

References (10)

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2. Canadian Multicentre Transplant Study Group. A randomized clinical trial of cyclosporine in cadaveric renal transplantation. N Engl J Med 1983; 309: 809.
3. Halloran P, Ludwin D, Aprile M, and the Canadian Multicentre Transplant Study Group. Comparison of antilymphocyte globulin-Imuran, cyclosporine and antilymphocyte globulin-cyclosporine therapy for cadaver renal transplantation. Transplant Proc 1985; 17: 1201.
4. O'Keefe SJ, Tamura J, Kincaid RL, Tocci MJ, O'Neil EA. FK506 and CsA sensitive activation of the interleukin-2 promoter by calcineurin. Nature 1992; 357: 692.
5. Kahan BD. Drug therapy: cyclosporine. N Engl J Med 1989; 321: 1725.
6. Batiuk TD, Pazderka FR, Halloran PF. Calcineurin activity is only partially inhibited in leukocytes of cyclosporine-treated patients. Transplantation 1995; 59: 1400.
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8. Ferraresso M, Kahan B. New immunosuppressive agents for pediatric transplantation. Pediatr Nephrol 1993; 7: 567.
9. Ettenger RB, Blifeld C, Prince H, et al. The pediatric nephrologists dilemma: growth after renal transplantation and its interaction with age as a possible immunologic variable. J Pediatr 1987; 111: 1022.
10. Kahan BD, Grevel J. Optimization of cyclosporine therapy in renal transplantation by a pharmacokinetic strategy [Overview]. Transplantation 1988; 46: 631.