Fine specificity of the antibody response to a synthetic peptide from the fusion protein and protection against measles virus-induced encephalitis in a mouse model

Journal of General Virology

Volumn 78, Issue 12, 1997, Pages 3227-3232

  Partidos, C D ^a   Ripley, J ^b   Delmas, A ^c   Obeid, O E ^b   Denbury, A ^b   Steward, M W ^b  

^a ROYAL VETERINARY COLLEGE   (United Kingdom)

^b LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^c CENTRE DE BIOPHYSIQUE MOLÉCULAIRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE; FREUND ADJUVANT; HYBRID PROTEIN; MEASLES ANTIBODY; MEASLES VACCINE; SYNTHETIC PEPTIDE;

ACTIVE IMMUNIZATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY PRODUCTION; ANTIBODY RESPONSE; ANTIGEN RECOGNITION; ARTICLE; CIRCULAR DICHROISM; CONTROLLED STUDY; ENCEPHALITIS; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; IMMUNIZATION; IMMUNOGENICITY; MASS SPECTROMETRY; MEASLES VIRUS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN STRUCTURE;

ANIMALIA; MEASLES VIRUS;

EID: 0030829921     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/0022-1317-78-12-3227     Document Type: Article

References (17)

1. Ellman, G. L. (1959). Tissue sulfhydryl groups. Archives of Biochemistry and Biophysics 82, 70-77.
2. Francis, M. J., Fry, C. M., Rowlands, D. J., Bittle, J. L., Houghton, R. A., Lerner, R. A. & Brown, F. (1987). Immune response to uncoupled peptides of foot and mouth disease virus. Immunology 61, 1-6.
3. Lefrancois, L. (1984). Protection against lethal viral infection by neutralizing and non neutralizing monoclonal antibodies: distinct mechanisms of action in vivo. Journal of Virology 51, 208-214.
4. Liebert, U. G. & ter Meulen, V. (1987). Virological aspects of measles virus-induced encephalomyelitis in Lewis and BN rats. Journal of General Virology 68, 1715-1722.
5. Love, A., Rydbeck, R., Utter, G., Orvell, C., Kristensson, K. & Norrby, E. (1986). Monoclonal antibodies against the fusion protein are protective in necrotizing mumps meningoencephalitis. Journal of Virology 58, 220-222.
6. Meloen, R. H., Casal, J. I., Dalsgaard, K. & Langeveld, J. P. M. (1995). Synthetic peptide vaccines - success at last. Vaccine 13, 885-886.
7. Merz, D. C., Scheid, A. & Choppin, P. W. (1980). The importance of antibody to fusion protein (F) of paramyxoviruses in the prevention of spread of infection. Journal of Experimental Medicine 151, 275-288.
8. Obeid, O. E., Partidos, C. D., Howard, C. R. & Steward, M. W. (1995). Protection against morbillivirus-induced encephalitis by immunization with a rationally designed synthetic peptide vaccine containing B and T cell epitopes from the fusion protein of measles virus. Journal of Virology 69, 1420-1428.
9. Partidos, C. D., Stanley, C. M. & Steward, M. W. (1991). Immune responses in mice following immunization with chimeric synthetic peptides representing B and T cell epitopes of measles virus proteins. Journal of General Virology 72, 1293-1299.
10. Portner, A., Scroggs, R. A. & Neave, C. W. (1987). The fusion glycoprotein of Sendai virus: sequence analysis of an epitope involved in fusion and virus neutralization. Virology 157, 556-563.
11. Rajan, R. & Balaram, P. (1996). A model for the interaction of trifluoroethanol with peptides and proteins. International Journal of Peptide and Protein Research 48, 328-336.
12. Richardson, C., Hull, D., Greer, P., Hasel, K., Berkovich, A., Englund, G., Bellini, W., Rima, B. & Lazzarini, R. (1986). The nucleotide sequence of the mRNA encoding the fusion protein of measles virus (Edmonston strain): a comparison of fusion proteins from several different paramyxoviruses. Virology 155, 508-523.
13. Steward, M. W., Stanley, C. M. & Obeid, O. E. (1995). A mimotope from a solid phase peptide library induces a measles virus neutralizing and protective antibody response. Journal of Virology 69, 7668-7673.
14. Varsanyi, T. M., Utter, G. & Norrby, E. (1984). Purification, morphology and antigenic characterization of measles virus envelope components. Journal of General Virology 65, 355-366.
15. Wild, T. F., Bernard, A., Spehner, D. & Drillien, R. (1992). Construction of vaccinia virus recombinants expressing several measles virus proteins and analysis of their efficacy in vaccination of mice. Journal of General Virology 73, 359-367.
16. Ziegler, D., Fournier, P., Berbers, G. A. H., Steuer, H., Wiesmuller, K.-H., Fleckenstein, B., Schneider, F., Jung, G., King, C.-C. & Muller, C. P. (1996). Protection against measles virus encephalitis by monoclonal antibodies binding to a cystine loop domain of the H protein mimicked by peptides which are not recognized by maternal antibodies. Journal of General Virology 77, 2479-2489.
17. Zhong, L. & Johnson, W. C (1992). Environment affects amino acid preference for secondary structure. Proceedings of the National Academy of Sciences, USA 89, 4462-4465.