Multifaceted roles for IGFBP-1 in human endometrium during implantation and pregnancy

Annals of the New York Academy of Sciences

Volumn 828, Issue , 1997, Pages 146-156

  Giudice, Linda C ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHORIONIC GONADOTROPIN; CYTOKINE; GROWTH FACTOR; INTEGRIN; SOMATOMEDIN BINDING PROTEIN 1; STEROID HORMONE;

CONFERENCE PAPER; DECIDUA; EMBRYO; EMBRYO DEVELOPMENT; ENDOMETRIUM; FEMALE; HUMAN; INTRAUTERINE GROWTH RETARDATION; NIDATION; PREECLAMPSIA; PREGNANCY; PREMATURE FETUS MEMBRANE RUPTURE; PROTEIN BINDING; PROTEIN SYNTHESIS; SPONTANEOUS ABORTION; TROPHOBLAST; UTERINE CERVIX; VAGINA SECRETION;

EID: 0030829839     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1997.tb48533.x     Document Type: Conference Paper

References (81)

1. NOYES, R. W., A. T. HERTIG & J. ROCK. 1950. Dating the endometrial biopsy. Fertil. Steril. 1: 3.
2. GIUDICE, L. C. 1994. Growth factors and growth modulators in human uterine endometrium: Their potential relevance to reproductive medicine. Fertil. Steril. 61: 1-17.
3. MURPHY, L. J., L. C. MURPHY & H. G. FRIESEN. 1987. A role for the insulin-like growth factors as estromedins in the rat uterus. Trans. Assoc. Am. Physicians 99: 204-214.
4. KOISTINEN, R., N. KALKINNEN, M.-L. HUHTALA, M. SEPPALA, H. BOHN & E.-M. RUTANEN. 1986. Placental protein 12 is a decidual protein that binds somatomedin and has an identical N-terminal amino acid sequence with somatomedin-binding protein from human amniotic fluid. Endocrinology 118: 1375-1378.
5. BELL, S. C., S. R. PATEL, J. A. JACKSON & G. T. WAITES. 1988. Major secretory protein of human decidualized endometrium in pregnancy is an insulin-like growth factor binding protein. J. Endocrinol. 118: 317-328.
6. JULKUNEN, M., R. KOISTINEN, K. AALTO-SETALA, M. SEPPALA, O. A. JANNE & K. KONTULA. 1988. Primary structure of human IGFBP/placental protein 12 and tissue expression of its mRNA. FEBS Lett. 236: 295-301.
7. JULKUNEN, M., R. KOISTINEN, A.-M. SUIKKARI, M. SEPPALA & O. A. JANNE. 1990. Identification by hybridization histochemistry of human endometrial cells expressing mRNAs encoding a uterine β-lactoglobulin homologue and insulin-like growth factor-binding protein-1. Mol. Endocrinol. 4: 700-707.
8. BOEHM, K. D., M. DAIMON, I. G. GORODESKI, L. A. SHEEAN, W. H. UTIAN & J. ILAN. 1990. Expression of the insulin-like and platelet-derived growth factor genes in human uterine tissues. Mol. Reprod. Dev. 27: 93-101.
9. GIUDICE, L. C., B. A. DSUPIN & J. C. IRWIN. 1992. Steroid and peptide regulation of insulin-like growth factor binding proteins secreted by human endometrial stromal cells is dependent on stromal differentiation. J. Clin. Endocrinol. Metab. 75: 1235-1241.
10. GIUDICE, L. C., B. A. DSUPIN, I. H. JIN, T. H. VU & A. R. HOFFMAN. 1993. Differential expression of mRNAs encoding insulin-like growth factors and their receptors in human uterine endometrium and decidua. J. Clin. Endocrinol. Metab. 76: 1115-1122.
11. GIUDICE, L. C., J. C. IRWIN, B. A. DSUPIN, L. DE LAS FUENTES, I. H. JIN, T. H. VU & A. R. HOFFMAN. 1994. Insulin-like growth factors (IGFs), IGF binding proteins (IGFBPs), and IGFBP protease in human uterine endometrium: Their potential relevance to endometrial cyclic function and maternal-embryonic interactions. In The Insulin-like Growth Factors and Their Regulatory Proteins. R. C. Baxter, P. D. Gluckmann & R. G. Rosenfeld, Eds.: 351-361. Excerpta Med. Int. Congr. Ser. 1056. Amsterdam.
12. ZHOU, J., B. A. DSUPIN, L. C. GIUDICE & C. A. BONDY. 1994. Insulin-like growth factor system gene expression in human endometrium during the menstrual cycle. J. Clin. Endocrinol. Metab. 79: 1723-1734.
13. HAN, V. K. M., N. BASSETT, J. WALTON & J. R. G. CHALLIS. 1996. The expression of insulin-like growth factor (IGF) and IGF-binding protein (IGFBP) genes in the human placenta and membranes: Evidence for IGF-IGFBP interactions at the feto-maternal interface. J. Clin. Endocrinol. Metab. 81: 2680-2693.
14. GIUDICE, L. C., D. A. MILKOWSKI, G. LAMSON, R. G. ROSENFELD & J. C. IRWIN. 1991. Insulin-like growth factor binding proteins (IGFBP-2 and IGFBP-3) in human endometrium: Steroid-dependent messenger RNA expression and protein synthesis. J. Clin. Endocrinol. Metab. 72: 779-787.
15. IRWIN, J. C., L. DE LAS FUENTES, B. A. DSUPIN & L. C. GIUDICE. 1993. Insulin-like growth factor (IGF) regulation of human endometrial stromal cell function: Coordinate effects on IGF binding protein-1, cellular proliferation, and prolactin secretion. Regul. Pept. 48: 165-177.
16. FROST, R. A., J. MAZELLA & L. TSENG. 1993. Insulin-like growth factor binding protein-1 inhibits the mitogenic effect of insulin-like growth factors and progestins in human endometrial stromal cells. Biol. Reprod. 49: 104-111.
17. BOHN, H. & W. KRAUS. 1980. Isolierung and charakterisierung eines neuen plazentaspezifischen proteins (PP12). Arch. Gynecol. 229: 279-291.
18. LEE, P. D. K., D. R. POWELL, C. A. CONOVER & L. C. GIUDICE. 1997. Insulin-like growth factor binding protein-1: Recent findings and new directions. Proc. Soc. Exp. Biol. Med. In press.
19. FAZLEABAS, A. T., S. HILD-PERTITO & H. G. VERHAGE. 1995. The primate endometrium: Morphologic and secretory changes in early pregnancy. Semin. Reprod. Endocrinol. 13: 120-132.
20. RUTANEN, E.-M., R. KOISTINEN, T. WAHLSTROM, J. SJOBERG, U.-H. STENMAN & M. SEPPALA. 1984. Placental protein 12 (PP12) in the human endometrium: Tissue concentration in relation to histology and serum levels of PP12, progesterone, and oestradiol. Br. J. Obstet. Gynecol. 91: 377-381.
21. RUTANEN, E.-M., R. KOISTINEN, T. WAHLSTROM, H. BOHN, T. RANTA & M. SEPPALA. 1985. Synthesis of placental protein 12 by human decidua. Endocrinology 116: 1304-1309.
22. RUTANEN, E.-M., R. KOISTINEN, J. SJOBERG, M. JULKUNEN, T. WAHLSTROM, H. BOHN, et al. 1986. Synthesis of placental protein 12 by human endometrium. Endocrinology 118: 1067-1071.
23. RUTANEN, E.-M., M. MENABAWEY, K. ISAKA, H. BOHN, T. CHARD & J. G. GRUDZINSKAS. 1986. Synthesis of placental protein 12 by decidua from early pregnancy. J. Clin. Endocrinol. Metab. 63: 675-679.
24. 1-globulin, and insulin-like growth factor-binding protein, during the menstrual cycle. J. Endocrinol. Metab. 67: 1100-1104.
25. 1-globulin, an insulin-like growth factor-binding protein: Immunohistological localization in the decidua and placenta during pregnancy employing monoclonal antibodies. J. Endocrinol. 120: 351-357.
26. BELL, S. C., J. A. JACKSON, J. ASHORE, H. H. ZHU & L. TSENG. 1991. Regulation of insulin-like growth factor-binding protein-1 synthesis and secretion by progestin and relaxin in long-term cultures of human endometrial stromal cells. J. Clin. Endocrinol. Metab. 72: 1014-1019.
27. RUTANEN, E.-M., E. GONZALEZ, J. SAID & G. D. BRAUNSTEIN. 1991. Immunohistochemical localization of the insulin-like growth factor binding protein-1 in female reproductive tissues by monoclonal antibodies. Endocr. Pathol. 2: 132-138.
28. BRYANT-GREENWOOD, G. D., E.-M. RUTANEN, S. PARTANEN, T. K. COELHO & S. Y. YAMAMOTO. 1993, Sequential appearance of relaxin, prolactin, and IGFBP-1 growth and differentiation of the human endometrium. Mol. Cell. Endocrinol. 95: 23-29.
29. GIUDICE, L. C., N. A. MARTINA, L. DE LAS FUENTES, R. A. CRYSTAL & M. L. DRUZIN. 1997. Insulin-like growth factor binding protein-1 (IGFBP-1) at the maternal-fetal interface and IGF-I, IGF-II, and IGFBP-1 in the circulation of women with severe pre-eclampsia. Am. J. Obstet. Gynecol. 176: 751-758.
30. IRWIN, J. C., D. KIRK, R. J. B. KING, M. M. QUIGLEY & R. B. L. GWATKIN. 1989. Hormonal regulation of human endometrial stromal cells in culture: An in vitro model for decidualization. Fertil. Steril. 52: 761-768.
31. IRWIN, J. C., W. H. UTIAN & R. L. ECKERT. 1991. Sex steroids and growth factors differentially regulate the growth and differentiation of cultured human endometrial stromal cells. Endocrinology 129: 2385-2392.
32. ROSENBERG, M., J. MAZELLA & L. TSENG. 1991. Relative potency of relaxin, insulin-like growth factors, and insulin on the prolactin production in progestin-primed human endometrial stromal cells in long-term culture. Ann. N. Y. Acad. Sci. 622: 138-144.
33. BRICE, A. L., J. E. CHEETHAM, V. N. BOLTON, N. C. W. HILL & P. N. SCHOFIELD. 1989. Temporal changes in the expression of the insulin-like growth factor II gene associated with tissue maturation in the human fetus. Development 106: 543-554.
34. THRAILKILL, K. M., D. R. CLEMMONS, W. H. BUSBY, JR. & S. HANDWERGER. 1990. Differential regulation of IGFBP secretion from human decidual cells by IGF-I, insulin, and relaxin. J. Clin. Invest. 86: 878-883.
35. MARK, S. P., N. A. MARTINA, J. C. IRWIN & L. C. GIUDICE. 1996. Cytokine regulation of IGFBP-1 production in decidualized endometrial stromal cells. Am. Soc. Reprod. Med. Annual Meeting, Boston, MA. Abstr. O-007: 84.
36. KARIYA, M., H. KANZAKI, K. TAKAKURA, K. IMI, N. OKAMOTO, N. EMI, Y. KARIYA & T. MORI. 1991. Interleukin-1 inhibits in vitro decidualization of human endometrial stromal cells. J. Clin. Endocrinol. Metab. 73: 1170-1174.
37. FRANK, G. R., A. K. BRAR, H. JIKIHARA, M. I. CEDARS & S. HANDWERGER. 1995. Interleukin-1β and the endometrium: An inhibitor of stromal cell differentiation and possible autoregulator of decidualization in humans. Biol. Reprod. 52: 184-191.
38. TANG, B. & E. GURPIDE. 1993. Direct effects of gonadotropins on decidualization of human endometrial stromal cells. J. Steroid Biochem. Mol. Biol. 47:115-121.
39. HAN, S. W., Z. M. LEI, J. S. SANFILIPPO & C. V. RAO. 1995. Human chorionic gonadotropin as a new regulator of human endometrial cell differentiation into decidua. 77th Annual Meeting of the US Endocrine Society, Washington, DC. Abstr. P2-84.
40. MOY, E., L. M. KIMZEY, L. M. NELSON & D. L. BLITHE. 1996. Glycoprotein hormone α-subunit functions synergistically with progesterone to stimulate differentiation of cultured human endometrial stromal cells to decidualized cells: A novel role for free α-subunit in reproduction. Endocrinology 137: 1332-1339.
41. REN, S. G. & G. D. BRAUNSTEIN. 1990. Progesterone and human chorionic gonadotropin do not stimulate PP-12 or prolactin production by human decidual tissue in vitro. J. Clin. Endocrinol. Metab. 70: 983-989.
42. Li, T. C., E. SERLE, M. A. WARREN & I. D. COOKE. 1993. Is endometrial development in the peri-implantation period influenced by high concentrations of LH in the follicular phase? Hum. Reprod. 8: 1021-1024.
43. ZHOU, J. & C. BONDY. 1993. Anatomy of the human ovarian insulin-like growth factor system. Biol. Reprod. 48: 467-474.
44. STETLER-STEVENSON, W. G., S. AZNAVOORIAN & L. A. LIOTTA. 1993. Tumor cell interactions with the extracellular matrix during invasion and metastasis. Annu. Rev. Cell Biol. 9: 541-573.
45. HOSSENLOPP, P., B. SEGOVIA, C. LASSARRE, M. ROGHANI, M. BREDON & M. BINOUX. 1990. Evidence of enzymatic degradation of IGFBPs in the "150K" complex during pregnancy. J. Clin. Endocrinol. Metab. 71: 797-805.
46. GIUDICE, L. C., E. M. FARRELL, H. PHAM & R. G. ROSENFELD. 1990. Insulin-like growth factor binding proteins in maternal serum throughout gestation and in the puerperium: Effects of a serum protease activity. J. Clin. Endocrinol. Metab. 71: 806-816.
47. RITVOS, O., T. RANTA, J. JALKANEN, A.-M. SUIKKARI, R. VOUTILAINEN, H. BOHN & M. SEPPALA. 1989. IGFBP from human decidua inhibits the binding and biological action of IGF-I in cultured choriocarcinoma cells. Endocrinology 122: 2150-2157.
48. 1 integrin by means of its Arg-Gly-Asp sequence. Proc. Natl. Acad. Sci. USA 90: 10553.
49. FISHER, S. J. & C. H. DAMSKY. 1993. Human cytotrophoblast invasion. Cell Biol. 4: 183-188.
50. 1 integrin in human cytotrophoblasts and inhibits their invasion into decidualized endometrial stromal cells in vitro. Growth Regul. In press.
51. IRVING, J. A. & P. K. LALA. 1995. Functional role of cell surface integrins on human trophoblast cell migration: Regulation by TFG-β, IGF-II, and IGFBP-1. Exp. Cell Res. 217: 419-429.
52. FRIEDMAN, S. A., R. N. TAYLOR & J. M. ROBERTS. 1991. Pathophysiology of preeclampsia. Clin. Perinatol. 4: 661-682.
53. PAGE, E. W. 1953. The Hypertensive Disorders of Pregnancy. C. C. Thomas. Springfield, MA. pp. 52-55.
54. KHONG, T. Y., F. DEWOLF, B. ROBERTSON & I. BROSENS. 1986. Inadequate maternal vascular response to placentation in pregnancies complicated by pre-eclampsia and by small-for-gestational age infants. Br. J. Obstet. Gynecol. 93: 1049-1059.
55. MOODLEY, J. & R. RAMSAROOP. 1989. Placental bed morphology in black women with eclampsia. S. Afr. Med. J. 75: 376-378.
56. ZHOU, Y., C. H. DAMSKY, K. CHIU, J. M. ROBERTS & S. J. FISHER. 1993. Preeclampsia is associated with abnormal expression of adhesion molecules by invasive cytotrophoblasts. J. Clin. Invest. 91: 950-960.
57. THAN, G. N., I. F. CSABA, D. G. SZABO, A. A. ARANY, Z. J. BOGNAR & H. BOHN. 1984. Serum levels of placental-specific tissue protein 12 (PP12) in pregnancy complicated by pre-eclampsia, diabetes, or twins. Arch. Gynecol. 236: 41-45.
58. IINO, K., J. SJOBERG & M. SEPPALA. 1986. Elevated circulating levels of a decidual protein, placental protein 12, in preeclampsia. Obstet. Gynecol. 68: 58-60.
59. VARMA, M., C. J. M. DE GROOT, S. LANYI & R. N. TAYLOR. 1993. Evaluation of plasma insulin-like growth factor-binding protein-3 as a potential predictor of pre-eclampsia. Am. J. Obstet. Gynecol. 169: 995-999.
60. DE GROOT, C. J. M., T. H. O'BRIEN & R. N. TAYLOR. 1996. Biochemical evidence of impaired trophoblast invasion of decidual stroma in women destined to have pre-eclampsia. Am. J. Obstet. Gynecol. 175: 24-29.
61. CREASY, R. K. & R. RESNIK. 1989. Intrauterine growth retardation. In Maternal-Fetal Medicine: Principles and Practice. R. K. Creasy & R. Resnik, Eds.: 547-563. Saunders. Philadelphia, PA.
62. D'ERCOLE, A. J. 1992. The insulin-like growth factors and in utero growth. Growth Genet. Horm. 8: 1-5.
63. CHARD, T. 1994. Insulin-like growth factors and their binding proteins in normal and abnormal human fetal growth. Growth Regul. 4: 91-100.
64. BANG, P., L. C. GIUDICE & R. G. ROSENFELD. 1994. Insulin-like growth factors (IGFs) and IGF binding proteins as endocrine growth factors in the human fetus and neonate. In Frontiers in Endocrinology. P. C. Sizonenko, M. L. Aubert & J.-D. Vassalli, Eds. 6: 197-212. Ayers-Serono Symposia. Geneva.
65. HOWELL, R. J. S., L. A. PERRY, N. S. CHOGLAY, H. BOHN & T. CHARD. 1985. Placental protein-12 (PP12): A new test for the prediction of the small-for-gestational-age infant. Br. J. Obstet. Gynaecol. 92: 1141-1144.
66. HALL, K., U. HASSON, G. LUNDIN & V. SARA. 1986. Serum levels of somatomedins and somatomedin-binding protein in pregnant women with type I and gestational diabetes and their infants. J. Clin. Endocrinol. Metab. 63: 1300-1306.
67. WANG, H. S., L. A. PERRY, J. KANISIUS, R. K. ILES, H. M. P. HOLLY & T. CHARD. 1991. Purification and assay of insulin-like growth factor binding protein-2: Measurement of circulating levels throughout pregnancy. J. Endocrinol. 128: 161-168.
68. CRYSTAL, R. A. & L. C. GIUDICE. 1991. Insulin-like growth factor binding protein profiles in human fetal cord sera: Ontogeny during gestation and differences in newborns with intrauterine growth retardation and large for gestational age newborns. In Modern Concepts of Insulin-like Growth Factors. E. M. Spencer, Ed.: 395-408. Elsevier. New York.
69. LANGFORD, K. S., W. F. BLUM, K. NICOLAIDES, A. M. MCGREGOR & J. P. MIELL. 1993. Insulin-like growth factor binding proteins-1 and -2 are markedly elevated in fetuses with impaired growth and uteroplacental insufficiency. J. Endocrinol. 139(Suppl.): 96.
70. VERHAEGHE, J., R. VAN BREE, E. VAN HERCK, J. LAUREYS, R. BOUILLON & F. A. VAN ASSCHE. 1993. C-peptide, insulin-like growth factor 1 and 3 and insulin-like growth factor binding protein-1 in umbilical cord serum: Correlations with birth weight. Am. J. Obstet. Gynecol. 169: 89-97.
71. REECE, E. A., A. WIZNITZER, E. LE, C. J. HOMKO, H. BEHRMAN & E. M. SPENCER. 1994. The relation between human fetal growth and fetal blood levels of insulin-like growth factors I and II, their binding proteins, and receptors. Obstet. Gynecol. 84: 88-95.
72. GIUDICE, L. C., F. DE ZEGHER, S. E. GARGOSKY, B. A. DSUPIN, R. L. HINTZ & R. G. ROSENFELD. 1995. Insulin-like growth factors and their binding proteins in the term and preterm human fetus and neonate with normal and extremes of intrauterine growth. J. Clin. Endocrinol. Metab. 80: 1548-1555.
73. DICHIARRA, T., A. ESTRATIADATIS & E. ROBERTSON. 1990. A growth deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting. Nature 345: 78-80.
74. LIU, J.-P., J. BAKER, A. S. PERKINS, E. J. ROBERTSON & A. EFSTRATIADIS. 1993. Mice carrying null mutations of the genes encoding insulin-like growth factor (Igf-I) and type 1 IGF receptor (Igf1r). Cell 75: 73-82.
75. PANNIER, E. P., J. C. IRWIN & L. C. GIUDICE. 1994. Insulin-like growth factor binding proteins in human fetus: Tissue-specific protein secretion, immunologic characterization, and gene expression. Am. J. Obstet. Gynecol. 171: 746-752.
76. HILL, D., D. R. CLEMMONS, S. C. RILEY, N. BASSET & J. R. G. CHALLIS. 1993. Immunohistochemical localization of insulin-like growth factors (IGFs) and IGF binding proteins-1, -2, and -3 in human placenta and fetal membranes. Placenta 14: 1-12.
77. CRAWFORD, R. A. F., F. A. HILLS, A. FARKAS & T. CHARD. 1995. Elevated levels of insulin-like growth factor binding protein-1 in fetal distress. Br. J. Obstet. Gynaecol. 102: 538-540.
78. HILLS, F., R. CRAWFORD, S. HARDING, A. FARKAS & T. CHARD. 1994. The effects of labor on maternal levels of insulin-like growth factor binding protein-1. Am. J. Obstet. Gynecol. 171: 1292-1295.
79. HAKALA-ALA-PIETILA, T. H., R. A. KOISTINEN, R. K. SALONEN & M. T. SEPPALA. 1993. Elevated second-trimester amniotic fluid concentration of insulin-like growth factor binding protein-1 in fetal growth retardation. Am. J. Obstet. Gynecol. 169: 35-39.
80. RUTANEN, E.-M., F. PEKONEN & T. KARKKAINEN. 1993. Measurement of insulin-like growth factor binding protein-1 in cervical/vaginal secretions: Comparison with the ROM-check membrane immunoassay in the diagnosis of ruptured fetal membranes. Clin. Chim. Acta 214: 713-717.
81. LOCKWOOD, C. H., R. WEIN, D. CHEIN, A. GHADINI, M. ALVAREZ & R. L. BERKOWITZ. 1994. Fetal membrane rupture is associated with the presence of insulin-like growth factor binding protein-1 in vaginal secretions. Am. J. Obstet. Gynecol. 171: 146-150.