Linkage analysis of complex traits using affected sibpairs: Effects of single-locus approximations on estimates of the required sample size

Genetic Epidemiology

Volumn 14, Issue 4, 1997, Pages 389-401

  Todorov, A A ^a   Borecki, I B ^a   Rao, D C ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Affected sibpair method; Complex traits; Epistasis; Power analysis; Two locus genetic models

Indexed keywords

ARTICLE; COMPUTER PROGRAM; GENE FREQUENCY; GENE LOCUS; GENETIC LINKAGE; GENETIC RISK; PENETRANCE; PREVALENCE; QUANTITATIVE TRAIT; SAMPLE; SIBLING;

GENE FREQUENCY; HUMANS; LINKAGE (GENETICS); MATHEMATICAL COMPUTING; MODELS, GENETIC; MODELS, STATISTICAL; NUCLEAR FAMILY; RISK ASSESSMENT; SAMPLE SIZE; SOFTWARE;

EID: 0030829369     PISSN: 07410395     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2272(1997)14:4<389::AID-GEPI4>3.0.CO;2-Z     Document Type: Article

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