Management of Progressive Metastatic Prostate Cancer

ONCOLOGY

Volumn 11, Issue 10, 1997, Pages 1551-1560

  Waselenko, Jamie K ^a   Dawson, Nancy A ^a  

^a WALTER REED ARMY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGLUTETHIMIDE; ANTIANDROGEN; BICALUTAMIDE; CHLORMADINONE; CLODRONIC ACID; CYCLOPHOSPHAMIDE; DIETHYLSTILBESTROL; DOXORUBICIN; ESTRAMUSTINE; ETIDRONIC ACID; ETOPOSIDE; FLUTAMIDE; GONADORELIN; GONADORELIN DERIVATIVE; HYDROCORTISONE; KETOCONAZOLE; LIAROZOLE; MEGESTROL ACETATE; MITOXANTRONE; NILUTAMIDE; PACLITAXEL; PAMIDRONIC ACID; PHENYLACETIC ACID; PREDNISONE; R 72521; RHENIUM 186; STRONTIUM 89; SURAMIN; TAMOXIFEN CITRATE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VINBLASTINE;

ARTICLE; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER SURVIVAL; CANCER THERAPY; HORMONAL THERAPY; HUMAN; PROSTATE CANCER; QUALITY OF LIFE; TREATMENT PLANNING;

ANDROGEN ANTAGONISTS; ANDROGENS; DIPHOSPHONATES; DISEASE PROGRESSION; HORMONES; HUMANS; MALE; PROSTATIC NEOPLASMS; QUALITY OF LIFE; SUBSTANCE WITHDRAWAL SYNDROME; SURAMIN; TESTIS;

EID: 0030828844     PISSN: 08909091     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (95)

1. Parker SL, Tong TT, Bolden S, et al: Cancer statistics, 1997 CA Cancer J Clin 41:5-27, 1997.
2. Klein LA: Prostatic carcinoma. N Engl J Med 300:824-833, 1979.
3. Huggins C, Hodges CV: Studies on prostatic cancer: 1. The effects of castration, of estrogen, and of androgen injection on serum phosphatases in metastatic carcinoma of the prostate. Cancer Res 1:293-297, 1941
4. Parmer H, Lightman SL, Allen L, et al: Randomized controlled study of orchiectomy vs long acting D-try-6-LHRH microcapsules in advanced proslatic carcinoma. Lancet 2:1201-1205, 1985.
5. Crawford ED, Eisenberger MA, McLeod DG, et al: A controlled trial of leuprolide with and without flutamide in prostatic carcinoma. N Engl J Med 321:419-424, 1989.
6. Janknegt RA, Abbou CC, Bartoletti R, et al: Orchiectomy and nilutamide or placebo as treatment of metastatic prostatic cancer in a multinational double-blind randomized trial. J Urol 149:77-83, 1993.
7. Bertagna C, DeGery A, Hucher M, et al: Efficacy of the combination of nilutamide plus orchiectomy in patients with metastatic prostatic cancer: A meta-analysis of seven randomized double-blinded trials 91056 patients. Br J Urol 73:396-402, 1994.
8. Prostate Cancer Trialists Collaborative Group: Maximum androgen blockade in advance prostate cancer: an overview of 22 randomised trials with 3283 deaths in 5710 patients. Lancet 346265-269, 1995.
9. Caubet J-F, Tosteson TD, Dong W, et al: Meta analysis of published randomized clinical trials for MAB in prostate cancer (abstract 654) Proc Am Soc Clin Oncol 15-254, 1996.
10. Klugo RC, Farah RN, Cerny JC: Bilateral orchiectomy for carcinoma of prostate: Response of serum testosterone and clinical response to estrogen therapy. Urology 17:49-50, 1981.
11. Nesbit RM, Baum WC: Endocrine control of prostatic carcinoma. Clinical and statistical survey of 1818 cases. JAMA 143:1317-1320, 1950.
12. Bjorn CL, Gray CP, Strauss E: Orchiectomy after presumed estrogen failure in the treatment of carcinoma of the prostate. West J Med 130:363-364, 1979.
13. Fowler JE, Whitmore WF: The response of metastatic adenocareinoma of the prostate 10 exogenous testosterone. J Urol 126:372-375, 1981.
14. Silver RI, Straus FH, Vogelzang NJ, et al: Response to orchiectomy following zoladex therapy for metastatic prostate carcinoma. Urology 37:17-21, 1991.
15. Hussain M, Wolf M, Marshall E, et al: Effects of continued androgen-deprived therapy and other prognostic factors on response and survival in phase II chemotherapy trials for hormone-refractory prostate cancer. A Southwest Oncology Group Report. J Clin Oncol 12:1868-1875, 1994.
16. Taylor CD, Elson P, Trump DL: Importance of continued testicular suppression in hormone refractory prostate cancer. J Clin Oncol 11:2167-2172, 1993.
17. Taplin ME, Bubley GJ, Shuster TD, et al. Mutation of the androgen receptor gene in meta static androgen-independent prostate cancer. N Engl J Med 332:1393-1398, 1995.
18. Figg WD, McCall NA, Reed E, et al: The in vitro response of four antisteroid receptor agents on the hormone responsive prostate cancer cell line LNCaP. Oncology Reports 2:295-298, 1995.
19. Wilding G, Chen M, Gelman EP: Aberrant response in vitro of hormone-responsive prostate cancer cells to anti-androgens. Prostate 14:103-115, 1989.
20. Small EJ, Srinivas S: The anti-androgen withdrawal syndrome: Experience in a large cohort of unselected advanced prostate cancer patients. Cancer 76:1428-1434, 1995.
21. Scher HI, Kelly WK: Flutamide withdrawal syndrome: Its impact on clinical trials in hormone-refractory prostate cancer. J Clin Oncol 11:1566-1572, 1993.
22. Figg WD, Sartor O, Cooper MR, et al. Prostate specific antigen decline following the discontinuation of flutamide in patients with stage D2 prostate cancer. Am J Med 98:412-414, 1995.
23. Small FJ, Carroll PR: Prostate specific antigen decline after Casodex withdrawal: Evidence for an anti-androgen withdrawal syndrome. Urology 43:408-410, 1994.
24. Small EJ, Schellhammer P, Venner P, et al: A double-blind assessment of anti-androgen withdrawal from Casodex or Eulexin therapy while continuing luteinizing hormone releasing hormone analogue therapy for patients with stage D2 prostate cancer (abstract 658). Proc Am Soc Clin Oncol 15:255, 1996
25. Dawson NA, McLeod DG: Dramatic prostate specific antigen decline in response to discontinuation of megestrol acetate in advanced prostate cancer: Expansion of the anti-androgen withdrawal syndrome J Urol 153:1946-1947, 1995.
26. Wehbe TW, Wehbe P, Akerly III W, et al: PSA response to megace withdrawal in hormone refractory prostate cancer (HRPC) (abstract 667). Proc Am Soc Clin Oncol 15:257, 1996.
27. Scher HI, Zhang ZF, Nanus D, et al: Hormone and antihormone withdrawal' Implications for the management of androgen-independent prostate cancer. Urology 47(suppl 1A):61-69, 1996.
28. Dupont A, Gomez JL, Cusan L, et al: Response to flutamide withdrawal in advanced prostate cancer in progression under combination therapy. J Urol 150:908-913, 1993.
29. Sartor O, Cooper M, Weinberger M, et al: Surprising activity of flutamide withdrawal, when combined with aminoglutethimide, in "hormonerefractory" prostate cancer. J Natl Cancer Inst 86:222-227, 1994.
30. Figg WD, Dawson NA, Middleman MN et al. Flutamide withdrawal and concomitant initiation of aminoglutethimide in patients with hormone-refractory prostate cancer. Acta Oncol 35:763-765, 1996.
31. Liebertz C, Kelly WK, Theodoulou M et al: High dose casodex for prostate cancer: PSA decline in patients with flutamide withdrawal responses (abstract 603). Proc Am Soc Clin Oncol 14:232, 1995
32. Fenton MA, Rode P, Constatine M et al: Bicalutamide for androgen-independent prostate cancer (abstract 684) Proc Am Soc Clin Oncol 15:262, 1996.
33. Kucuk O, Blumenstein, Moinponr C, et al: Phase II mal of Casodex in advanced prostate cancer patients who failed conventional hormonal manipulation: A SWOG Study (SWOG 9235) (abstract 618) Proc Am Soc Clin Oncol 15:245, 1996.
34. Dawson NA, Small EJ, Conaway M, et al: Megestrol acetate in men with hormone-refractory prostate cancer: Prostate specific antigen response and anti-androgen withdrawal: CALGB 9181 (abstract 601). Proc Am Soc Clin Oncol 15:241, 1996.
35. Bergan RC, Blagosklonny M, Dawson NA, et al: Significant activity by high dose tamoxifen in hormone refractory prostate cancer (abstract 637). Proc Am Soc Clin Oncol 14:241, 1995.
36. Trump DL, Havlin KH, Messing EM, et al High-dose ketoconazole in advance hormone-refractory prostate cancer. Endocrinologic and clinical effects. J Clin Oncol 7:1093-1098, 1989.
37. Small EJ, Egan B, Apodaca D, et al: Keto conazole retains activity in advanced prostate cancer patients with progression despite flutamide withdrawal. J Urol 4(5): 1204-1207, 1997.
38. Miller CM, Hinman F: Cortisone treatment in advance carcinoma of the prostate. J Urol 72:485-496, 1954.
39. Tannock I, Gospodarowicz M, Meakin W, et al: Treatment of metastatic prostatic cancer with low-dose prednisone: Evaluation if pain and quality of life as pragmatic indices of response. J Clin Oncol 7:590-597, 1989.
40. Harland SJ, Duchesne GM: Suramin and prostate cancer: The role of hydrocortisone (letter) Eur J Cancer 28A:1295, 1992.
41. Storlie JA, Buckner JC, Wiseman GA, et al: Prostate specific antigen levels and clinical response to low-dose dexamethasone for hormone refractory metastatic prostate cancer (abstract 726). Proc Am Soc Clin Oncol 13:235, 1994.
42. Tew KD, Stearns, ME: Estramustine-A nitrogen mustard/steroid with antimicrotubule activity. Pharmacol Ther 43:299-319, 1989.
43. Benson RC: Role of estramustine phosphate in the treatment of prostate cancer, in Schaefers H (ed). Estracyst, Scientific Edition 2, pp 35-64. Utrecht, 1988.
44. Roth BJ, Yeap BY, Wilding G, et al: Taxol in advanced, hormone-refractory carcinoma of the prostate. Cancer 72:2457-2460, 1993.
45. Hussain M, Pienta KJ, Redman BG, et al: Oral etoposide in the treatment of hormone refractory prostate cancer Cancer 74:100-103, 1994.
46. Pienta KJ, Lehr JE: Inhibition of prostate cancer growth by estranmstine and etoposide: Evidence for interactions at the nuclear matrix. J Urol 149:1622-1625, 1993.
47. Mareel MM, Storme GA, Dragonett CH, et al: Anti invasive activity of estramustine on malignant MO4 cells and DU-145 human prostate carcinoma cells in vitro. Cancer Res 48:1842-1849, 1988.
48. Speicher LA, Barone L, Tew KD: Combined antimicrotubule activity of estramustine and taxol in human prostatic carcinoma cell lines. Cancer Res 52:4433-4440, 1992.
49. Pienta KJ, Redman B, Hussain M, et al: Phase II evaluation of oral estramustine and oral etoposide in hormone refractory adenocarcinoma of the prostate. J Clin Oncol 12:2005-2012, 1994.
50. Hudes G, Nathan F, Chapman A, et al: Combined antimicrotubule therapy of metastatic prostate cancer with 96-hr paclitaxel and estramustine: Activity in hormone-refractory disease (HRPC) (abstract 622). Proc Am Soc Clin Oncol 14:237, 1995.
51. Hudes GR, Greenberg R, Krigel RL, et al: Phase II study of estramustine and vmblastine, two microtubule inhibitors, in hormone-refractory prostate cancer. J Clin Oncol 10:1754-1761, 1992.
52. Reese D, Burris H, Bellegrun A, et al: A phase I/II study of navelbine (vinorelbine) and estramustine in the treatment of hormone refractory prostate cancer (abstract 673). Proc Am Soc Clin Oncol 15:259, 1996.
53. Pienta KJ, Flaherty E, Hussain M, et al: Report of an extended phase II trial of oral estramustine and oral etoposide in the treatment of hormone refractory prostate cancer patients (abstract 681). Proc Am Soc Oncol 15:261, 1996.
54. Trudeau M, Aronson S, Bazinet M: Preliminary results of estramustine and vinblastine as primary treatment for metastatic prostatic cancer (abstract 662). Proc Am Soc Clin Oncol 15:256, 1996.
55. Wehbe T, Akerley W, Sloan L, et al. Strontium-89, estramustine, and vinblastine in hormone refractory prostate carcinoma: Concurrent chemoradiotherapy (abstract 682). Proc Am Soc Clin Oncol 15:261, 1996.
56. Kelly WK, Scher HI, Mazumdar M, et al: Prostate-specific antigen as a measure of disease outcome in metastatic hormone-refractory proslate cancer. J Clin Oncol 11:607-615, 1993.
57. Raghavan D, Cox K, Pearson BS, et al. Oral cyclophosphamide for the management of hormone-refractory prostate cancer Br J Urol 72:625-628, 1993
58. Small EJ, Srinivas S, Egan B, et al Doxorubicin and dose-escalated cyclophosphamide with granulocyte colony-stimulating factor for the treatment of hormone-resistant prostate cancer. J Clin Oncol 14:1617-1625, 1996.
59. Tannock T, Gospodarowicz M, Meakin W, et al. Treatment of metastatic prostatic cancer with low-dose prednisone: Evaluation if pain and quality of life as pragmatic indices of response. J Clin Oncol 7:590-597, 1989.
60. Moore MJ, Osoba D, Murphy K, et al: Use of palliative endpoints to evaluate the effects of mitoxantrone and low-dose prednisone in patients with hormonally resistant prostate cancer. J Clin Oncol 12:689-694, 1994
61. Tannock IF, Osoba D, Stockler MR, et al Chemotherapy with mitoxantrone plus prednisone or prednisone alone for symptomatic hormone-resistant prostate, cancer: a Canadian randomized trial with palliative endpoints. J Clin Oncol 14:1756-1764, 1996.
62. Kantoff PW, Conaway M, Winer E, et al: Hydrocortisone with and without mitoxantrone in patients with hormone-refractory prostate cancer: Preliminary results from a prospective randomized Cancer and Leukemia Group B (9182) comparing chemotherapy to best supportive care (abstract 2013). Proc Am Soc Clin Oncol 14:1748, 1996.
63. Silberstein EB: The treatment of painful osseous metastases with phosphorus-32-labeled phosphates. Semin Oncol 20, No.3 2(suppl):10-21, 1993.
64. Crawford ED, Kozlowski JM, Debruyne FMI, et al: The use of strontium-89 for palliation of pain form bone metastases associated with hormone-refractory prostate cancer. Urology 44:481-485, 1994.
65. Porter AT, McEwan AJB, Powe JE, et al Results of a randomized phase III trial to evaluate the efficacy of strontium-89 adjuvant to local field external beam irradiation in the management of endocrine resistant metastatic prostate cancer. Int J Radiat Oncol Biol Phys 25:805-813, 1993.
66. Quilty PM, Kirk D, Bolger JJ, et al: A comparison of the palliative effects of strontium-89 and external beam radiotherapy in metastatic prostate cancer. Radiother Oncol 31:33-40, 1994.
67. Farhanght M, Holmes RA, Volkert WA, et al: Samarium-153-EDTMP: Pharmacokinetic toxicity and pain response using an escalating dose schedule in treatment of metastalic bone cancer J Nucl Med 33:1451-1458, 1992.
68. Collins C, Eary JF, Donaldson G, et al: Samarium-153-EDTMP in bone metastases of hormone refractory prostate carcinoma: A phase I/II trial. J Nucl Med 34:1839-1844, 1993.
69. Bayouth JE, Macey DJ, Kasi LP, et al: Dosimetry and toxicity of samarium-153-EDTMP administered for bone pain due to skeletal metastases. J Nucl Med 35:63-69, 1994.
70. Quick D, Reid R, Hoskin P, et al: Efficacy and safety of 153Sm-EDTMP in alleviating the pain of bone metastases in patients with prostate carcinoma (abstract 1654). Proc Am Soc Clin Oncol 15.514, 1996.
71. Maxon HR, Thomas, SR, Hertzberg VS, et al: Rhenium-186 hydroxyethylidene Diphosphonate for the treatment of painful osseous metastases. Seinin Nucl Med 23:33-40, 1992
72. Silberstein EB: Radiopharmaceutical therapy of cancer pain from bone metastases, in Prostate Cancer pp 261-268. Somerset, New Jersey, Wiley-Liss, 1994.
73. Urwin GH, Percival RC, Harris S, et al: Generalized increase in bone resorption in carcinomaof the prostate. Br J Urol 57:721-723, 1985.
74. Clarke NW, McClure J, George NJR: Effects of disodium pamidronate in metastatic prostate cancer (abstract). Eur J Cancer 27(suppl 2):117, 1991.
75. Hawkins F: Suramin: With special reference to onchocerciasis. Adv Pharmacol Chemother 15-289-322, 1978.
76. Stem CA, La Rocca RV, Thomas R, et al: Suramin: An anticancer drug with a unique mechanism of action. J Clin Oncol 7:499-508, 1989.
77. Myers C, Cooper M, Stein CA, et al: Suramin: A novel growth factor antagonist with activity in hormone-refractory metastatic prostate cancer J Clin Oncol 10:881-889, 1992.
78. Eisenberger MA, Sinibaldi VJ, Reyno LM, et al. Phase I and clinical evaluation of a pharmacologically guided regimen of suramin in patients with hormone-refractory prostate cancer. J Clin Oncol 13:2174-2186, 1995.
79. Dawson NA, Cooper MR, Figg WD, et al: Antitumor activity of suramin in hormone-refractory prostate cancer controlling for hydrocortisone treatment and flutamide withdrawal as potentially confounding variables. Cancer 76:453-462, 1995.
80. Kelly WK, Curley T, Leibertz C, et al. Prospective evaluation of hydrocortisone and suramin in patients with androgen-independent prostate cancer. J Clin Oncol 13:2208-2213, 1995.
81. Bitton RJ, Figg WD, Venzon DJ, et al: Pharmacologic variables associated with the development of neurologic toxicity in patients treated with suramin. J Clin Oncol 13:2223-2229, 1995.
82. Dawson NA, Lush RM, Steinberg SM, et al: Suramin-induced neuiropenia. Eur J Cancer 32A: 1534-1539, 1996.
83. Kobayashi K, Vokes EE, Vogelzang NJ, et al: Phase I study of suramin given by intermittent infusion without adaptive control in patients with advanced cancer. J Clin Oncol 13:2196-2207, 1996
84. Bowden CJ, Figg WD, Dawson NA, et al: A phase I/II study of continuous infusion suramin in patients with hormone-refractory prostate cancer: Toxicity and response. Cancer Chemother Pharmacol (39)1-2:1-8, 1996.
85. Ferrari AC, Waxman S: Differentiation agents in cancer therapy, in Cancer Chemotherapy and Biologic Response Modifiers Annual, pp 337-366. New York, Elsevier Science B.V., 1994.
86. Samid D, Shack S, Myers CE: Selective growth arrest and phenotypic reversion of prostate cancer cells in vitro by nontoxic pharmacologic concentrations of phenylacetate. J Clin Invest 91(5):22W-2295, 1993.
87. Walls RG, Thibault A, Wood C, et al: Phenylacetate induces the production of prostate specific antigen in prostate cancer cells: In vitro and in vivo studies (abstract 46). Proc Am Soc Clin Oncol 14:86, 1995.
88. Bowling MK, Nelson JB, Tong KP, et al: Biomarker responses in men with advanced prostate cancer (PCA) to infusional phenylbutyrate (abstract 43). Proc Am Soc Clin Oncol 15:94, 1996
89. Seidmon EJ, Trump DL, Kreis, W, et al: Phase I/II dose-escalation study of liazorole in patients with stage D. hormone-refractory carcinoma of the prostate Ann Surg Oncol 2(6) 550-556, 1995
90. Smith J, Andriole G, Ahmann F, et al: Effects of liazorole on PSA levels in patients with relapsed stage D prostate cancer (abstract 636). Proc Am Soc Clin Oncol 15:250, 1996.
91. Smith PH, Bono A, da Silva C, et al: Some limitations of the radioisotope bone scan in patients with metastatic prostatic cancer. Cancer 66.1009-1016, 1990.
92. Pollen JJ, Witztum KF, Ashburn WL: The flare phenomenon on radionucleotide bone scan in metastatic prostate cancer. Am J Roentgenol 142:773-776, 1984.
93. Smith DC, Dunn RL, Strawderman MS, et al: Change in serum prostate specific antigen as a marker of response to cytotoxic therapy for hormone refractory prostate cancer. J Clin Oncol, 1997 (in press).
94. Dawson NA, Eligibility and response criteria in hormone refractory prostate cancer (PMPC): A need for consensus (abstract 1129). Proc Am Soc Clin Oncol 16:317A, 1997.
95. Kelly WK, Steineck G, Mazumdar M, et al: Post-therapy changes in biochemical markers in patients with androgen independent prostate cancer (abstract 606). Proc Am Soc Clin Oncol 14:233, 1995.