Difference in brown adipose tissue effector response and associated thermoresponsiveness of ventromedial hypothalamic (VMH) neurons of 21°C vs. 4°C acclimatized rats to scrotal thermal stimulation

Brain Research

Volumn 770, Issue 1-2, 1997, Pages 18-25

  Li, Qiang ^a   Thornhill, Jim ^a  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

Author keywords

Cold acclimatization; Neuronal adaptation; Scrotal thermal stimulation; Thermoresponsiveness; VMH warm and cold responsive neuron

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; BROWN ADIPOSE TISSUE; COLD ACCLIMATIZATION; HEAT SENSITIVITY; HYPOTHALAMUS VENTROMEDIAL NUCLEUS; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SCROTUM; THERMAL STIMULATION;

ACCLIMATIZATION; ADIPOSE TISSUE, BROWN; ANESTHETICS, INTRAVENOUS; ANIMALS; BODY TEMPERATURE; BODY TEMPERATURE REGULATION; COLD; ELECTROPHYSIOLOGY; HEAT; MALE; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; SCROTUM; URETHANE; VENTROMEDIAL HYPOTHALAMIC NUCLEUS;

EID: 0030828054     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(97)00739-7     Document Type: Article

References (38)

1. Amir S. Stimulation of the paraventricular nucleus with glutamate activates interscapular brown adipose tissue thermoregulation in rats. Brain Res. 508:1990;152-155.
2. Amir S., Shizgal P., Rompre P. Glutamate injection into the suprachiasmatic nucleus with glutamate activate interscapular brown adipose tissue thermoregulation in rats. Brain Res. 498:1989;140-144.
3. Amir S., Schiavetto A. Injection of prostaglandin E2 into the anterior hypothalamic preoptic area activate brown adipose tissue thermogenesis in the rat. Brain Res. 528:1990;138-142.
4. J.A. Boulant, Hypothalamic control of thermoregulation neurophysiological basis, in: P.J. Morgane, J. Panksepp (Eds.), Behavioral Studies of the Hypothalamus, Handbook of the Hypothalamus, vol. 3, part A, Marcel Dekker, New York, 1980, pp. 1-82.
5. J.A. Boulant, Neurophysiological aspects of thermoregulation, in: L.C.H. Wang (Ed.), Advances in Comparative and Environmental Physiology, Springer-Verlag, Berlin-Heidelberg, 1989, pp. 118-160.
6. Boulant J.A., Hardy J.D. The effect of spinal and skin temperatures on the firing rate and thermosensitivity of preoptic neurones. J. Physiol. 240:1974;639-660.
7. Bruck K., Wunnernberg W., Gallmerier H., Ziehm B. Shift of threshold temperature of shivering and heat polypnea as a model of thermal adaptation. Pflüger's Arch. 321:1970;159-172.
8. Freeman P.H., Wellman P.J. Brown adipose tissue thermogenesis induced by low level electrical stimulation of hypothalamus in rats. Brain Res Bull. 18:1987;7-11.
9. Hellon R.F., Misra N.K. Neurones in the ventrobasal complex of the rat thalamus responding to scrotal skin temperature changes. J. Physiol. 232:1973;389-399.
10. Hellon R.F., Hensel H., Schafer K. Thermal receptors in the scrotum of the rat. J. Physiol. 248:1975;349-357.
11. H. Hensel, M. Banet, Thermoreceptor activity, insulative and metabolic changes in cold and warm adapted cats, in: Y. Houdas, J.D. Guieu (Eds.), New Trends in Thermal Physiology, Proceedings of the Satellite Symposium on Thermal Stimulation, 1978, Lille, France, 27th International Congress of Physiological Science, Paris, 1978, pp. 53-55.
12. Hensel H., Schafer K. Static and dynamic activity of cold receptor in cats after long-term exposure to various temperatures. Pflügers Arch. 392:1982;291-294.
13. Himms-Hagen J. Neural control of brown adipose tissue thermogenesis, hypertrophy, and atrophy. Frontiers Neuroendocrinol. 12:1991;38-43.
14. J. Himms-Hagen, Brown adipose tissue and cold-acclimation, in: P. Trayhurn, D.G. Nicholls, Brown Adipose Tissue Arnold, London, 1986, pp. 214-268.
15. Hinckel P., Crittante L., Bruck K. Inhibitory effects of the lower brain stem on shivering. J. Therm. Biol. 8:1983;129-131.
16. Hinckel P., Perschel W.T. Influence of cold and warm acclimation on neuronal responses in the lower brain stem. Can. J. Physiol. Pharmacol. 65:1987;1281-1289.
17. Hinckel P., Schroder-Rosenstock K. Central thermal adaptation of lower brain stem units in the guinea-pig. Pflüger's Arch. 359:1982;344-346.
18. Iggo A. Cutaneous thermoreceptors in primates and sub-primates. J. Physiol. 200:1969;403-430.
19. Jahns R. Types of neuronal responses in the rats thalamus to peripheral temperature changes. Exp. Brain Res. 23:1975;157-166.
20. Kiyohara T., Miyata S., Nakamura T., Shido O., Nakashima T., Shibata M. Differences in Fos expression in the rat brains between cold and warm ambient exposures. Brain Res Bull. 38:1995;193-201.
21. Kurosawa M. Reflex changes in thermogenesis in the interscapular brown adipose tissue in response to thermal stimulation of the skin via sympathetic efferents in anaesthetized rats. J. Auton. Nerv. Sys. 33:1991;15-24.
22. Li Q., Thornhill J.A. Neuronal activity changes of ventromedial hypothalamic(VMH) neurons and associated temperature responses in rats following scrotal thermal stimulation. Can. J. Physiol. Pharmacol. 71:1993;604-610.
23. Li Q., Thornhill J.A. Specific thermal responsiveness of ventromedial hypothalamic (VMH) neurons to localized scrotal heating and cooling. J. Physiol. 492.3:1996;851-865.
24. Li Q., Thornhill J.A. Thermal responsiveness of ventromedial hypothalamic neurons (VMH) of cold- and room temperature-acclimated rats. Soc. Neurosci. Abstr. 21:1995;350.6. San Diego, CA.
25. Li Q., Thornhill J.A. A functional medial preoptic nucleus(MPO) is required for scrotal thermal stimulation to alter the neuronal activity of thermoresponsive ventromedial hypothalamic (VMH) neurons. Brain Res. 716:1996;134-140.
26. Li Q., Thornhill J.A. The thermoresponsiveness of ventromedial hypothalamic (VMH) neurons following repeated scrotal thermal stimulation of rats maintained at normothermic or acutely hypothermic core temperature. Brain Res. 749:1997;29-34.
27. Miyata S., Ishiyama M., Shido O., Nakashima T., Shibata M., Kiyohara T. Central mechanism of neural activation with cold acclimation of rats using Fos immunohistochemistry. Neurosci. Res. 22:1995;209-218.
28. 14C]Deoxyglucose incorporation into rat brain regions during hypothalamic or peripheral thermal stimulation. Am. J. Physiol. 248:1985;R84-R92.
29. Nakayama T., Ishikawa Y., Tsurutani T. Projection of scrotal thermal afferents to the preoptic and hypothalamic neurons in rats. Pflüger's Arch. 380:1979;59-64.
30. Niijima A., Rohner-Jeanrenaud F., Jeanrenaud B. Role of ventromedial hypothalamus on sympathetic efferents of brown adipose tissue. Am. J. Physiol. 247:1984;R650-R654.
31. G. Paxinos, C. Watson, The Rat Brain in Stereotaxic Coordinates, 2nd ed. Academic Press, New York, 1986.
32. Perkins M.N., Rothwell N.J., Stock M.J., Stone T.W. Activation of brown adipose tissue in hypothalamic obesity in rats. Nature. 289:1981;401-402.
33. Schingnitz G., Werner J. Responses of thalamic neurons to thermal stimulation of the limbs, scrotum and tongue in the rat. J. Therm. Biol. 5:1980;53-61.
34. Taylor D.C.M. The effects of nucleus raphe magnus lesions on an ascending thermal pathway in the rat. J. Physiol. 326:1982;309-318.
35. Thornhill J.A., Halvorson I. Brown adipose tissue thermogenic responses of rats induced by central stimulation: effect of age and cold acclimation. J. Physiol. 426:1990;317-333.
36. Thornhill J.A., Halvorson I. Differences in brown adipose tissue thermogenic responses between Long-Evans and Sprague-Dawley rats. Am. J. Physiol. 263:1992;R59-R69.
37. Thornhill J., Halvorson I. Electrical stimulation of the posterior and ventromedial hypothalamic nuclei cause specific activation of shivering and nonshivering thermogenesis. Can. J. Physiol. Pharmacol. 72:1993;89-96.
38. Werner J., Schingnitz G., Hensel H. Influence of cold adaptation on the activity of thermoresponsive neurons in thalamus and midbrain of the rats. Pflüger's Arch. 391:1981;327-330.