Synthesis of Enantiomerically and Diastereomerically Pure Cyclopentanols by Asymmetric Cyclocarbolithiation of 5-Alkenyl Carbamates

Angewandte Chemie (International Edition in English)

Volumn 36, Issue 16, 1997, Pages 1764-1766

  Woltering, Michael J ^a   Fröhlich, Roland ^a   Hoppe, Dieter ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

( ) sparteine; Asymmetric synthesis; Carbanions; Carbolithiations; Cyclopentanols

Indexed keywords

EID: 0030827702     PISSN: 05700833     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.199717641     Document Type: Article

References (33)

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16. The crude carboxylic acid was converted into the methyl ester 5g by treatment with diazomethane. A small amount of the carboxylate presumably epimerizes under the work-up conditions.
17. 3 to be greater than 95%.
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26. Crystallographic data (excluding structure factors) for the structures reported in this paper have been deposited with the Cambridge Crystallographic Data Centre as supplementary publication no. CCDC-100 367. Copies of the data can be obtained free of charge on application to The Director, CCDC, 12 Union Road, Cambridge CB21EZ, UK (fax: int. code +(1223)336-033; e-mail; deposit@chemcrys.cam.ac.uk).
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