MIC2, TdT, bcl-2, and CD34 expression in paraffin-embedded high-grade lymphoma/acute lymphoblastic leukemia distinguishes between distinct clinicopathologic entities

Human Pathology

Volumn 28, Issue 10, 1997, Pages 1158-1165

  Soslow, Robert A ^a   Bhargava, Vivek ^b   Warnke, Roger A ^b  

^a WEILL CORNELL MEDICAL CENTER   (United States)

^b NONE

Author keywords

12E7; bcl 2; CD34; High grade lymphoma; Lymphoblastic lymphoma; MIC2; Small noncleaved cell lymphoma; TdT

Indexed keywords

CD34 ANTIGEN;

ACUTE LYMPHOBLASTIC LEUKEMIA; ANTIGEN EXPRESSION; ARTICLE; B LYMPHOCYTE ACTIVATION; BLAST TRANSFORMATION; CANCER GRADING; FROZEN SECTION; HUMAN; HUMAN TISSUE; IMMUNOPEROXIDASE STAINING; IMMUNOPHENOTYPING; LYMPHOMA; MOLECULAR INTERACTION; TISSUE SECTION;

EID: 0030827249     PISSN: 00468177     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0046-8177(97)90254-9     Document Type: Article

References (46)

1. Levy R, Dilley J, Fox RI, et al: A human thymus-leukemia antigen defined by hybridoma monoclonal antibodies. Proc Natl Acad Sc U S A 76:6552-6556, 1979
2. Perlman EJ, Dickman PS, Askin FB, et al: Ewing's sarcoma: Routine diagnostic utilization of MIC2 analysis. HUM PATHOL 25:304-307, 1994
3. Ramani P, Rampling D, Link M: Immunocytochemical study of 12E7 in small round-cell tumors of childhood: An assessment of its sensitivity and specificity. Histopathology 23:557-561, 1993
4. Burgoyne PS: Genetic homology and crossing over in the X and Y chromosomes of mammals. Hum Genet 61:85-90, 1982
5. Gelin C, Aubrit F, Phalipon A, et al: The E2 antigen, a 32kd glycoprotein involved in T-cell adhesion processes, is the MIC2 gene product. EMBOJ 8:3253-3259, 1989
6. Goodfellow PJ, Darling SM, Thomas NS, et al: A pseudoautosomal gene in man. Science 234:740-743, 1986
7. Smith MJ, Goodfellow PJ, Goodfellow PN: The genomic organisation of the human pseudoautosomal gene MIC2 and the detection of a related locus. Hum Mol Genet 2:417-422, 1993
8. Hamilton G, Fellinger EJ, Schratter I, et al: Characterization of a human endocrine tissue and tumor-associated Ewing's sarcoma antigen. Cancer Res 48:6127-6134, 1988
9. Fellinger EJ, Garin-Chesa P, Su SL, et al: Biochemical and genetic characterization of the HBA71 Ewing's sarcoma cell surface antigen. Cancer Res 51:336-340, 1991
10. Janossy G, Hoffbrand AV, Greaves MF: Terminal transferase enzyme assay and immunological membrane markers in the diagnosis of leukemia: A multiparameter analysis of 300 cases. Br J Haematol 44:221-234, 1980
11. Bradstock K, Hoffbrand A, Ganeshaguru K, et al: Terminal deoxynucleotidyl transferase expression in acute non-lymphoid leukaemia: An analysis by immunofluorescence. Br J Haematol 47:133-143, 1981
12. Parreira A, Pombode, Oliveira M, et al: Terminal deoxynucleotidyl transferase positive acute myeloid leukaemia: An association with immature myeloblastic leukaemia. Br J Haematol 69:219-224, 1988
13. Schachner J, Kantarjian H, Dalton W, et al: Cytogenetic association and prognostic significance of bone marrow blast cell terminal transferase in patients with acute myeloblastic leukemia. Leukemia 2:667-671, 1988
14. Racklin B, Bearman R, Sheibani K, et al: The demonstration of terminal deoxynucleotidyl transferase on frozen tissue sections and smears by the avidin-biotin complex (ABC) method. Leukoc Res 7:431-437, 1983
15. Fetterhoff TJ, Parwaresch MR, Stein H, et al: Avidin-biotin amplification procedures for the detection of human terminal deoxynucleotidyl transferase in cell smears. Am J Clin Pathol 83:565-570 1985
16. Knowles DM: Non-Hodgkin's lymphomas: Immunologic and enzymatic markers useful in their evaluation. Prog Surg Pathol 2:71-105, 1980
17. Said JW, Shintaku IP, Pinkus GS: Immunohistochemical staining for terminal deoxynucleotidyl transferase (TdT): An enhanced method in routinely processed formalin-fixed tissue sections. Am J Clin Pathol 89:649-652, 1988
18. Halverson CA, Falini B, Taylor CR, et al: Detection of terminal transferase in paraffin sections with the immunoperoxidase technique. Am J Pathol 105:241-254, 1981
19. Beckstead JH: Improved antigen retrieval in formalin-fixed, paraffin-embedded tissues. Appl Immunohistochem 2:274-281, 1994
20. Soligo D, Delia D, Oriani A: Identification of CD34+ cells in normal and pathological bone marrow biopsies by QBEND 10 monoclonal antibody. Leukemia 5: 1026-1030, 1991
21. Civin Cl, Strauss LC, Brovall C, et al: Antigenic analysis of hematopoiesis. A hematopoietic progenitor cell surface antigen defined by a monoclonal antibody raised against KG-la cells. J Immunol 133:157-165, 1984
22. Terstappen LW, Huang S, Picker LJ: Flow cytometric assessment of human T-cell differentiation in thymus and bone marrow. Blood 79:666-677, 1992
23. Delia D, Lampugnani MG, Resnati M: CD34 expression is regulated reciprocally with adhesion molecules in vascular endothelial cells in vitro. Blood 81:1001-1008, 1993
24. Simmons DL, Satterthwaite AB, Tenen DG, et al: Molecular cloning of a cDNA encoding CD34, a sialomucin of human hematopoietic stem cells. J Immunol 148:267-271, 1992
25. Hanson CA, Ross CW, Schnitzer B: Anti-CD34 immunoperoxidase staining in paraffin sections of acute leukemia: Comparison with flow cytometric immunophenotyping. HUM PATHOL 23:26-32, 1992
26. AzizaJ, Mazerolles C, Selves J: Comparison of the reactivities of monoclonal antibodies QBEND 10 (CD34) and BNH9 in vascular tumors. Appl Immunohistochem 1:51-57, 1993
27. Quintanilla ML, Zukerberg LR, Harris NL: Prethymic adult lymphoblastic lymphoma: A clinicopathologic and immunohistochemical analysis. Am J Surg Pathol 16:1075-1084, 1992
28. Zutter M, Hockenbery D, Silverman G, et al: Immunolocalization of the bcl-2 protein within hematopoietic neoplasms. Blood 78:1062-1068, 1991
29. Pezzella F, Tse A, Cordell J, et al: Expression of the bcl-2 oncogene protein is not specific for the 14; 18 translocation. Am J Pathol 137:225-232, 1990
30. Said JW, Pinkus GS, Lones MA, et al: Expression of bcl-2 oncogene protein in malignant lymphomas, including Hodgkin's disease and non-Hodgkin's lymphomas of T-cell phenotype. Appl Immunohistochem 1:108-114, 1993
31. Bindl JM, Warnke RA: Advantages of detecting monoclonal antibody binding to tissue sections with biotin and avidin reagents in coplin jars. Am J Clin Pathol 85:490-493, 1977
32. Quintanilla-Martinez L, Preffer F, Rubin D, et al: CD20+ T-cell lymphoma: Neoplastic transformation of a normal T-cell subset. Am J Clin Pathol 102:483-489, 1994
33. Brownell MD, Sheibani K, Battifora H, et al: Distinction between undifferentiated (small noncleaved) and lymphoblastic lymphoma. Am J Surg Pathol 11:779-787, 1987
34. Murphy S: Childhood non-Hodgkin's lymphoma. N Engl J Med 299:1446-1448, 1978
35. Sheibani K, Nathwani BN, Winberg CD, et al: Antigenically defined subgroups of lymphoblastic lymphoma. Cancer 60:183-190, 1987
36. Sander CA, Jaffe ES, Gebhardt FC, et al: Mediastinal lymphoblastic lymphoma with an immature B-cell immunophenotype. Am J Surg Pathol 16:300-305, 1992
37. Sander CA, Medeiros LJ, Abruzzo LV, et al: Lymphoblastic lymphoma presenting in cutaneous sites. J Am Acad Dermatol 25:1023-1031, 1991
38. Weiss LM, Bindl JM, Picozzi VJ, et al: Lymphoblastic lymphoma: An immunophenotype study of 26 cases with comparison to T cell acute lymphoblastic leukemia. Blood 67:474-478, 1986
39. Link MP, Roper M, Dorfman RF, et al: Cutaneous lymphoblastic lymphoma with pre-B markers. Blood 61:838-841, 1983
40. Grogan T, Spier C, Wirt DP, et al: Immunologic complexity of lymphoblastic lymphoma. Diagn Immunol 4:81-88, 1986
41. Cossman J, Chused TM, Fisher RI, et al: Diversity of immunological phenotypes of lymphoblastic lymphoma. Cancer Res 43:4486-4490, 1983
42. Riopel M, Dickman PS, Link MP, et al: MIC2 Analysis in pediatric lymphomas and leukemias. HUM PATHOL 25:396-399, 1994
43. Ambros IM, Ambros PJ, Strehl S, et al: MIC2 is a specific marker for Ewing's sarcoma and peripheral primitive neuroectodermal tumors. Cancer 67:1886-1893, 1991
44. Orazi A, Cattoretti G, John K, et al: Terminal deoxynucleotidyl transferase staining of malignant lymphomas in paraffin sections. Mod Pathol 7:582-586, 1994
45. Orazi A, Cotton J, Cattoretti G, et al: Terminal deoxynucleotidyl transferase staining in acute leukemia and normal bone marrow in routinely processed paraffin sections. Am J Clin Pathol 102:640-645, 1994
46. Borowitz MJ, Shuster JJ, Civin CI, et al: Prognostic significance of CD34 expression in childhood B-precursor acute lymphocytic leukemia: A pediatric oncology group study. J Clin Oncol 8:1389-1398, 1990