Generalised seizure-induced changes in rat hippocampal glutamate but not GABA release are potentiated by repeated seizures

Neuroscience Letters

Volumn 234, Issue 2-3, 1997, Pages 143-146

  Rowley, Helen L ^a,b   Marsden, Charles A ^a   Martin, Keith F ^b  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b ABBOTT LABORATORIES   (United States)

Author keywords

Aminobutyric acid; Glutamate; Hippocampus; Maximal electroshock; Microdialysis; Repeated generalised seizures

Indexed keywords

4 AMINOBUTYRIC ACID RELEASE; AMINO ACID METABOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; EVOKED RESPONSE; GRAND MAL SEIZURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIPPOCAMPUS; LONG TERM POTENTIATION; MICRODIALYSIS; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANALYSIS OF VARIANCE; ANIMALS; ELECTROSHOCK; GAMMA-AMINOBUTYRIC ACID; GLUTAMIC ACID; HIPPOCAMPUS; MALE; MICRODIALYSIS; RATS; RATS, INBRED STRAINS; SEIZURES;

EID: 0030826132     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(97)00700-3     Document Type: Article

References (20)

1. Choi D.W. Glutamate neurotoxicity and diseases of the nervous system. Neuron. 1:1988;623-634.
2. Choi D.W., Maulucci-Gedde M., Kriegstein A.R. Glutamate neurotoxicity in cortical cell culture. J. Neurosci. 7:1987;357-368.
3. Curtis, D.R. and Johnston, G.A.R., Amino acid transmitters in the mammalian central nervous system, Ergeb. Physiol., 69 (1974) 97-188.
4. Finkbeiner S., Stevens C.F. Applications of quantitative measurements for assessing glutamate neurotoxicity. Proc. Natl. Acad. Sci. USA. 85:1988;4071-4074.
5. Fonnum F. Glutamate: a neurotransmitter in mammalian brain. J. Neurochem. 42:1984;1-11.
6. Glue P., Costello M.J., Pert A., Mele A., Nutt D.J. Regional neurotransmitter responses after acute and chronic electroconvulsive shock. Psychopharmacology. 100:1990;60-65.
7. Green A.R., Vincent N.D. The effect of repeated electroconvulsive shock on GABA synthesis and release in regions of rat brain. Br. J. Pharmacol. 92:1987;19-24.
8. Mangano R.M., Schwarcz R. Chronic infusion of endogenous excitatory amino acids into rat striatum and hippocampus. Brain Res. Bull. 10:1983;47-51.
9. Meldrum B.S. Epilepsy and γ-aminobutyric acid-mediated inhibition. Int. Rev. Neurobiol. 17:1975;1-36.
10. Meldrum B.S. Excitatory amino acid transmitters in epilepsy. Epilepsia. 32(Suppl. 2):1991;S1-S3.
11. Meldrum B.S. Excitotoxicity and selective neuronal loss in epilepsy. Brain Pathol. 3:1993;405-412.
12. Paxinos, G. and Watson, C., The Rat Brain in Stereotaxic Coordinates, 2nd edn., Academic Press, London, 1986.
13. Rowley H.L., Marsden C.A., Martin K.F. Differential effects of phenytoin and sodium valproate on seizure-induced changes in g-aminobutyric acid and glutamate release in vivo. Eur. J. Pharmacol. 294:1995;541-546.
14. Rowley H.L., Martin K.F., Marsden C.A. Decreased GABA release following tonic-clonic seizures is associated with an increase in extracellular glutamate in rat hippocampus in vivo. Neuroscience. 68:1995;415-422.
15. Rowley H.L., Martin K.F., Marsden C.A. Determination of in vivo amino acid neurotransmitters by high-performance liquid chromatography with o-phthalaldehyde-sulphite derivatisation. J. Neurosci. Methods. 57:1995;93-99.
16. Rowley, H.L., Martin, K.F. and Marsden, C.A., The significance of generalised seizure-induced changes in GABA and glutamate release. In J.L. Gonzalez-Mora, R. Borges and M. Mas (Eds.), Monitoring Molecules in Neuroscience, Proceedings of the 7th International Conference on in vivo Methods, University of La Laguna, Tenerife, 1996, pp. 186-188.
17. Schousboe A. Transport and metabolism of glutamate and GABA in neurons and glial cells. Int. Rev. Neurobiol. 22:1981;1-45.
18. Smith, S.E. and Sharp, T., Effects of repeated electroconvulsive shock (ECS) on extracellular levels of GABA, glutamate, and dopamine in the nucleus accumbens of the awake rat. In J.L. Gonzalez-Mora, R. Borges and M. Mas (Eds.), Monitoring Molecules in Neuroscience, Proceedings of the 7th International Conference on in vivo Methods, University of La Laguna, Tenerife, 1996, pp. 241-242.
19. Walker M.C., Galley P.T., Errington M.L., Shorvon S.D., Jefferys J.G.R. Ascorbate and glutamate release in the rat hippocampus after perforant path stimulation: a dialysis electrode study. J. Neurochem. 65:1995;725-731.
20. Zis A.P., Nomikos G.G., Brown E.E., Damsma G., Fibiger H.C. Neurochemical effects of electrically and chemically-induced seizures: an in vivo microdialysis study in the rat hippocampus. Neuropsychopharmacology. 7:1992;189-195.