Complement regulatory proteins in the salivary glands and saliva of Sjogren's syndrome patients and healthy subjects

Clinical and Experimental Rheumatology

Volumn 15, Issue 6, 1997, Pages 615-623

  Cuida, M ^a   Legler, D W ^a   Eidsheim, M ^a   Jonsson, R ^a  

^a UNIVERSITY OF BERGEN   (Norway)

Author keywords

Autoimmunity; Clusterin (SP40,40); Decay accelerating factor (CD55); Membrane cofactor protein (CD46); Protectin (CD59); Sjogren's syndrome

Indexed keywords

CD59 ANTIGEN; CLUSTERIN; DECAY ACCELERATING FACTOR; MEMBRANE COFACTOR PROTEIN;

ARTICLE; AUTOIMMUNITY; CLINICAL ARTICLE; CONTROLLED STUDY; EXOCRINE CELL; HUMAN; HUMAN TISSUE; INFLAMMATION; PRIORITY JOURNAL; SALIVA ANALYSIS; SALIVARY GLAND; SALIVARY GLAND FUNCTION; SJOEGREN SYNDROME; TISSUE DISTRIBUTION;

ANTIBODIES, MONOCLONAL; ANTIGENS, CD; ANTIGENS, CD46; ANTIGENS, CD55; ANTIGENS, CD59; BIOPSY; BLOTTING, WESTERN; CLUSTERIN; COMPLEMENT INACTIVATOR PROTEINS; COMPLEMENT SYSTEM PROTEINS; FEMALE; GLYCOPROTEINS; HUMANS; MEMBRANE GLYCOPROTEINS; MOLECULAR CHAPERONES; SALIVA; SALIVARY GLANDS, MINOR; SJOGREN'S SYNDROME;

EID: 0030825977     PISSN: 0392856X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. MOUTSOPOULOS HM, MANN DL, JOHNSON AH, CHUSED TM: Genetic differences between primary and secondary sicca syndrome. New Engl J Med 1979; 301: 761-3.
2. WHALEY K, CHISHOLM DM, GOUDIE RB et al: Salivary duct autoantibody in Sjögren's syndrome: correlation with focal sialadenitis in the labial mucosa. Clin Exp Immunol 1969; 4: 273-82.
3. ANDERSON LG, TARPLEY TM, TALAL N, CUMMINGS NA, WOLF RO, SCHALL GL: Cellular-versus-humoral autoimmune responses to salivary gland in Sjögren's syndrome. Clin Exp Immunol 1973; 13: 335-42.
4. MULLER-EBERHARD HJ: Molecular organization and function of the complement system. Ann Rev Biochem 1988; 57: 321-47.
5. MOFFAT GJ, LAPPIN D, BIRNIE GD, WHALEY K: Complement biosynthesis in human synovial tissue. Clin Exp Immunol 1989; 78: 54-60.
6. BREITNER S, STORKEL S, REICHEL W, LOOS M: Complement components C1q, C1r/C1s, and C1INH in rheumatoid arthritis. Arthritis Rheum 1995; 38: 492-8.
7. HEBERT LA, COSIO FG, BIRMINGHAM DJ: The role of the complement system in renal injury. Semin Nephrol 1992; 2: 408-27.
8. WIRTZ GH, PRICE RA, MUTCHLER BA, MILLER RW: The first component of complement as a constituent of human salivary sediment. Archs Oral Biol 1987; 32: 505-8.
9. WITTE DP, WELCH TR, BEISCHEL LS: Detection and cellular localization of human C4 gene expression in the renal tubular epithelial cells and other extrahepatic epithelial sources. Am J Pathol 1991; 39: 717-24.
10. MORGAN BP, MERI S: Membrane proteins that protect against complement lysis. Springer Semin Immunopathol 1994; 15: 369-96.
11. NICHOLSON-WELLER A, BURGE J, FEARON DT, WELLER PF, AUSTEN KF: Isolation of a human erythrocyte membrane glycoprotein with decay-accelerating activity for C3 convertases of the complement system. J Immunol 1982; 129: 184-9.
12. SEYA T, TURNER JR, ATKINSON JP: Purification and characterization of a membrane protein (gp45-70) that is a cofactor for cleavage of C3b and C4b. J Exp Med 1986; 163: 837-55.
13. ZALMAN LS, WOOD LM, MULLER-EBERHARD HJ: Isolation of a human erythrocyte membrane protein capable of inhibiting expression of homologous complement transmembrane channels. Proc Natl Acad Sci 1986; 83: 6975-9.
14. MURPHY BF, KIRSZBAUM L, WALKER ID, D'APICE AJF: SP-40,40, a newly identified normal human serum protein found in the SC5b-9 complex of complement and in the immune deposits in glomerulonephritis. J Clin Invest 1988; 81: 1858-64.
15. TSCHOPP J, FRENCH LE: Clusterin: modulation of complement function. Clin Exp Immunol 1994; 97 (Suppl. 2): 11-4.
16. VITALI C, BOMBARDIERI S, MOUTSOPOULOS HM, BALESTRIERI G: Preliminary criteria for the classification of Sjögren's syndrome. Arthritis Rheum 1993; 36: 340-7.
17. DANIELS TE: Labial salivary gland biopsy in Sjögren's syndrome; Assessment as a diagnostic criterion in 362 suspected cases. Arthritis Rheum 1984; 27: 147-56.
18. HSU SM, RAINE L, FANGER H: Use of avidin-biotin peroxidase complex (ABC) in immunoperoxidase techniques. A comparison between ABC and unlabeled antibody (PAP) procedures. J Histochem Cytochem 1981; 29: 577-80.
19. SCHAEFER ME, RHODES M, PRINCE S, MICHALEK SM, MCGHEE JR: A plastic intra-oral device for the collection of human parotid saliva. J Dent Res 1977; 56: 728-33.
20. LAEMMLI UK: Cleavage of structural proteins during the assembly of the head of bacteriophage T-4. Nature 1970; 227: 680-5.
21. NOSE M, KATOH M, OKADA N, KYOGOKU M, OKADA H: Tissue distribution of HRF 20, a novel factor preventing the membrane attack of homologous complement, and its predominant expression on endothelial cells in vivo. Immunology 1990; 70: 145-9.
22. MERI S, WALDMANN H, LACHMANN PJ: Distribution of protectin (CD59), a complement membrane attack inhibitor, in normal human tissues. Lab Invest 1991; 65: 532-7.
23. MEDOF ME, WALTER EI, RUTGERS JL, KNOWLES DM, NUSSENZWEIG V: Identification of the complement decay-accelerating factor (DAF) on epithelium and glandular cells and in body fluids. J Exp Med 1987; 165: 848-64.
24. JOHNSTONE RW, LOVELAND BE, MCKENZIE IFC: Identification and quantification of complement regulator CD46 on normal human tissues. Immunology 1993; 79: 341-7.
25. MERI S, VAKEVA A, LAARI T, LACHMANN PJ: Soluble forms of CD59-antigen: distribution in body fluids and functional activity. Complement Inflamm 1991; 8: 193.
26. HARA T, KURIYAMA S, KIYOHARA H, NAGASE Y, MATSUMOTO M, SEYA T: Soluble forms of membrane cofactor protein (CD46, MCP) are present in plasma, tears, and seminal fluid in normal subjects. Clin Exp Immunol 1992; 89: 490-4.
27. JENNE DE, TSCHOPP J: Molecular structure and functional characterization of a human complement cytolysis inhibitor found in blood and seminal plasma: identity to sulfated glycoprotein 2, a constituent of rat testis fluid. Proc Natl Acad Sci 1989; 86: 7123-27.
28. OGLESBY TJ, ALLEN CJ, LISZEWSKI MK, WHITE DJG, ATKINSON JP: Membrane cofactor protein (CD46) protects cells from complement-mediated attack by an intrinsic mechanism. J Exp Med 1992; 175: 1547-51.
29. BARDENSTEIN DS, DIETZ Y, LASS JH, MEDOF ME: Localization of the complement membrane attack complex inhibitor (CD59) in human conjunctiva and lacrimal gland. Curr Eye Res 1994; 13: 851-5.
30. THOMSEN BS, OXHOLM P, MANTHORPE R, NIELSEN H: Complement C3b receptors on erythrocytes, circulating immune complexes, and complement C3 split products in patients with primary Sjögren's syndrome. Arthritis Rheum 1986; 29: 857-62.
31. JONES J, LAFFAFIAN I, COOPER AM, WILLIAMS BD, MORGAN BP: Expression of complement regulatory molecules and other surface markers on neutrophils from synovial fluid and blood of patients with rheumatoid arthritis. Br J Rheumatol 1994; 33: 707-12.
32. DAVIES ME, HORNER A, LOVELAND BE, MCKENZIE IFC: Up-regulation of complement regulators MCP (CD46), DAF (CD55) and protectin (CD59) in arthritic joint disease. Scand J Rheumatol 1994; 23: 316-21.
33. BJØRGE L, SKEIE JENSEN T, ULVESTAD E, VEDELER CA, MATRE RA: The influence of tumor necrosis factor-α, interleukin-1β and interferon-γ on the expression and function of the complement regulatory protein CD 59 on the human colonie adenocarcinoma cell line HT29. Scand J Immunol 1995; 41: 350-6.
34. TANDON N, MORGAN BP, WEETMAN AP: Expression and function of membrane attack complex inhibitory proteins on thyroid follicular cells. Immunology 1992; 75: 372-77.