Detection of HHV-6 genotypes by in situ hybridization with variant-specific oligonucleotide probes

Journal of Virological Methods

Volumn 66, Issue 1, 1997, Pages 5-14

  Arivananthan, M ^a   Yadav, M ^a   Kumar, S ^b  

^a UNIVERSITY OF MALAYA   (Malaysia)

^b Seremban Hospital   (Malaysia)

Author keywords

Carcinoma; Digoxigenin; HHV 6A; HHV 6B; In situ hybridization; Probes

Indexed keywords

ARTICLE; BREAST CARCINOMA; CONTROLLED STUDY; GENOTYPE; HUMAN; HUMAN HERPESVIRUS 6; HUMAN TISSUE; IN SITU HYBRIDIZATION; LARYNX CARCINOMA; MOUTH CARCINOMA; OLIGONUCLEOTIDE PROBE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SALIVARY GLAND CARCINOMA; TUMOR BIOPSY; UTERINE CERVIX CARCINOMA; VIRUS CARCINOGENESIS; VIRUS DETECTION; VIRUS INFECTION; VIRUS TYPING;

DEOXYRIBONUCLEASE HINDIII; DNA, VIRAL; GENOTYPE; HERPESVIRUS 6, HUMAN; HUMANS; IN SITU HYBRIDIZATION; NEOPLASMS; OLIGONUCLEOTIDE PROBES; POLYMERASE CHAIN REACTION; TUMOR CELLS, CULTURED; VARIATION (GENETICS);

HERPESVIRIDAE; HUMAN HERPESVIRUS 6;

EID: 0030825466     PISSN: 01660934     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0166-0934(97)02198-8     Document Type: Article

References (36)

1. Aubin, J.T., Collandre, H., Candotti, D., Ingrand, D., Rouzioux, C., Burgard, M., Richard, S., Huraux, J.M. and Agut, H. (1991) Several groups among HHV-6 strains can be distinguished by Southern blotting and PCR. J. Clin. Microbiol. 29, 367-372.
2. Aubin, J.T., Poirel, L., Robert, C., Huraux, J.M. and Agut, H. (1994) Identification of human herpesvirus 6 variants A and B by amplimer hybridization with variant-specific oligonucleotides and amplification with variant-specific primers. J. Clin. Microbiol. 32, 2434-2440.
3. Chen, M., Popescu, N., Woodworth, C., Berneman, Z., Corbellino, M., Lusso, P., Ablashi, D.V. and DiPaolo, J.A. (1994) Human herpesvirus-6 infects epithelial cells and transactivates human papillomavirus gene expression. J. Virol. 68, 1173-1178.
4. Dewhurst, S., Chandran, B., McIntyre, K., Schnabel, K. and Hall, C. (1992) Phenotypic and genetic polymorphisms among Human herpesvirus-6 isolates from North American infants. Virology 190, 490-493.
5. Dewhurst, S., McIntyre, K., Schnabel, K. and Hall, C.B. (1993) Human herpesvirus-6 (HHV-6) variant B accounts for the majority of symptomatic primary HHV-6 infections in a population of U.S. infants. J. Clin. Microbiol. 31, 416-418.
6. Drobyski, W.R., Knox, K.K., Majewski, A. and Carrigan, D.R. (1994) Fatal encephalitis due to variant B human herpesvirus-6 infection in a bone marrow transplant recipient. N. Engl. J. Med. 330, 1356-1360.
7. Fox, J.D., Briggs, M., Ward, P.A. and Tedder, R.S. (1990) Human herpesvirus-6 in salivary glands. Lancet 336, 590-593.
8. Heiles, H.B.J., Genersch, E., Kessler, C., Neumann, R. and Eggers, H.J. (1988) In situ hybridization with digoxigenin-la-belled DNA of human papillomaviruses (HPV 16/18) in HeLa and SiHa cells. Biotechniques 6, 978-981.
9. Josephs, S.F., Salahuddin, S.Z., Ablashi, D.V., Schacter, F., Wong-Staal, F. and Gallo, R.C. (1986) Genomic analysis of the human B-lymphotropic virus. Science 234, 601-603.
10. Krueger, G.R.F., Ablashi, D.V., Josephs, S.F. and Balachandran, N. (1992) HHV-6 in atypical polyclonal lymphoproliferation (APL) and malignant lymphomas. In: D.V. Ablashi, G.R.F. Krueger and S.Z. Salahuddin (Eds.), HHV-6: Epidemiology, Molecular Biology and Clinical Pathology, Elsevier, Amsterdam, pp. 185-208.
11. Krueger, G.R.F., Manak, M., Bourgeois, N., Ablashi, D.V., Salahuddin, S.Z., Josephs, S.F., Buchbinder, A., Gallo, R.C., Berthold, F. and Tesch, H. (1989) Persistent active herpesvirus infection associated with atypical polyclonal lymphoproliferation and malignant lymphoma. Anticancer Res. 9, 1457-1476.
12. Krueger, G.R.F., Wasserman, K., De Clerck, L.S., Stevens, W.J., Bourgeois, N., Ablashi, D.V., Josephs, S.F. and Balachandran, N. (1990) Latent herpesvirus-6 in salivary and bronchial glands. Lancet 336, 1255-1256.
13. Langdon, J.D. and Partridge, M. (1992) Expression of tumour suppressor gene p53 in oral cancer. Br. J. Oral Maxillofac. Surg. 30, 214-220.
14. Lucas, R.B. (1976) Epidermoid tumours. In: Lucas, R.B. (Ed.), Pathology of Tumours of the Oral Tissue. Churchill Livingstone, UK, pp. 130-163.
15. Luppi, M., Barozzi, P., Marasca, R. and Torelli, G. (1994) Integration of human herpesvirus-6 (HHV-6) genome in chromosome 17 in two lymphoma patients. Leukemi 8 (Suppl. 1) 41-45.
16. Lusso, P., Salahuddin, S.Z., Ablashi, D.V., Gallo, R.C., Di-Marzo Veronese, F. and Markham, P.D. (1987) Diverse tropism of human B-lymphotropic virus (human herpesvirus-6). Lancet ii, 743-744.
17. Mitchell, B.S., Dhami, D. and Schumacher, U. (1992) In situ hybridization: a review of methodologies and applications in the biomedical sciences. Med. Lab. Sci. 49, 107-118.
18. 35S-based in situ hybridization methodologies for detection of human papillomavirus DNA. Lab. Invest 61, 471-475.
19. Pruksananonda, P., Hall, C.B., Insel, R., McIntyre, K., Pellett, P., Long, C., Schnabel, K., Pincus, P., Stamey, F., Dambaugh, T. and Stewart, J. (1992) Primary human herpesvirus-6 infection in young children. New Engl. J. Med. 326(22), 1445-1450.
20. Ranger-Rogez, S., Vidal, E., Labrousse, F., Riche, A., Vidal, J., Collineau, M., Liozon, F. and Denis, F. (1995) Large-scale study suggests no direct link between human herpesvirus-6 and primay Sjogren's syndrome. J. Med. Virol. 47, 198-203.
21. Razzaque, A. (1990) Oncogenic potential of HHV-6 DNA. Oncogene 5, 1365-1370.
22. Razzaque, A., Williams, O., Wang, J. and Rhim, J. (1993) Neoplastic transformation of immortalized human epidermal keratinocytes by two HHV-6 DNA clones. Virology 195, 113-120.
23. Saiki, R.K., Scharf, S., Faloona, F., Mullis, K.B., Horn, G.T., Erlich, H.A. and Arnheim, N. (1985) Enzymatic amplifica-tion of β-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia. Science 230, 1350-1354.
24. Salahuddin, S.Z., Ablashi, D.V., Markham, P.D., Josephs, S.F., Sturzenegger, S., Kaplan, M., Halligan, G., Biberfeld, P., Wong-Staal, F.W., Kramarsky, B. and Gallo, R.C. (1986) Isolation of a new virus, human β-lymphotropic virus (HBLV) in patients with lymphoproliferative disorders. Science 234, 596-601.
25. Shanavas, K.R., Kala, V., Vasudevan, D.M., VUayakumar, T. and Yadav, M. (1992) Anti-HHV-6 antibodies in normal population and in cancer patients in India. J. Exp. Pathol. 6, 95-105.
26. Shen, Y.Y., Huang, A.M., Jahan, N., Manak, M., Jaffe, E.S. and Levine, P.H. (1993) In situ hybridization detection of human herpesvirus 6 in biopsy specimens from Chinese patients with Non-Hodgkin's Lymphoma. Arch. Pathol. Lab. Med. 117, 502-506.
27. Stoler, M.H. and Ratliff, N.B. (1990) Potential and problems of the in situ molecular detection of viral genomes. Am. J. Clin. Pathol. 93, 714-716.
28. Sumiyoshi, Y., Kikuchi, M., Ohshima, K., Yoneda, S., Kobari, S., Takeshita, M., Eizuru, Y. and Minomishima, Y. (1993) Human herpesvirus-6 genomes in histiocytic necrotizing lymphoadenitis. Am. J. Clin. Pathol. 5, 609-614.
29. Torelli, G., Barozzi, P., Marasca, R., Cocconcelli, P., Merelli, E., Ceccherini-Nelli, L., Ferrari, S. and Luppi, M. (1995) Targeted integration of human herpesvirus 6 in the p-arm of chromosome 17 of human peripheral blood mononuclear cells in vivo. J. Med. Virol. 46, 178-188.
30. Torelli, G., Marasca, R., Luppi, M., Seileri, L., Ferrari, S., Narni, F., Mariano, M.T., Federico, M., Ceccherini, L., Bendinelli, M., Montagani, G., Montorsi, M. and Artusi, T. (1991) HHV-6 in human lymphomas: identification of specific sequences in Hodgkin's lymphomas by PCR. Blood 77, 2251-2258.
31. Warnakulasuriya, K.A.A.S. and Johnson, N.W. (1992) Expression of p53 mutant nuclear phosphoprotein in oral carcinomas and potentially malignant oral lesions. J. Oral Pathol. Med. 21, 404-408.
32. Weiss, L.M., Movahed, L.A., Berry, G.J. and Billingham, M.E. (1990) In situ hybridization for viral nuclei acids in heart and lung allograft biopsies. Am. J. Clin. Pathol. 93, 675-679.
33. Yadav, M., Chandrashekran, A., Vasudevan, D.M. and Ablashi, D.V. (1994) Frequent detection of human herpesvirus-6 in oral carcinoma. J. Natl. Cancer Institute 86, 1792-1794.
34. Yalcin, S., Karpuzoglu, T., Suleymanlar, G., Mutlu, G., Mukai, T., Yamamoto, T., Isegawa, Y. and Yamanishi, K. (1994) Human herpesvirus 6 and human herpesvirus 7 infections in renal transplant recipients and healthy adults in Turkey. Arch. Virol. 136, 183-190.
35. Yamamoto, T., Mukai, T., Kondo, K. and Yamanishi, K. (1994) Variation of DNA sequence in immediate-early gene of human herpesvirus 6 and variant identification by PCR. J. Clin. Microbiol. 32, 473-476.
36. Yamanishi, K., Okuno, T., Shiraki, K., Takahashi, M., Kondo, T., Asano, Y. and Kurata, T. (1988) Identification of HHV-6 as the causal agent for exanthem subitum. Lancet i, 1065-1067.