-
2
-
-
9044245305
-
ZD1694: A novel thymidylate synthase inhibitor with substantial activity in the treatment of patients with advanced colorectal cancer
-
Zalcberg JR, Cunningham D, Van Cutsem E, et al.: ZD1694: A novel thymidylate synthase inhibitor with substantial activity in the treatment of patients with advanced colorectal cancer. J Clin Oncol 1996, 14:716-721.
-
(1996)
J Clin Oncol
, vol.14
, pp. 716-721
-
-
Zalcberg, J.R.1
Cunningham, D.2
Van Cutsem, E.3
-
3
-
-
0029164564
-
ZD1694 (Tomudex): A new thymidylate synthase inhibitor with activity in colorectal cancer
-
Jackman AL, Farrugia DC, Gibson W, et al.: ZD1694 (Tomudex): a new thymidylate synthase inhibitor with activity in colorectal cancer. Eur J Cancer 1995, 31A:1277-1285.
-
(1995)
Eur J Cancer
, vol.31 A
, pp. 1277-1285
-
-
Jackman, A.L.1
Farrugia, D.C.2
Gibson, W.3
-
4
-
-
0025997350
-
ICI D1694, a quinazoline antifolate thymidylate synthase inhibitor that is a potent inhibitor of L1210 tumor cell growth in vitro and in vivo: A new agent for clinical study
-
Jackman AL, Taylor GA, Gibson W, et al.: ICI D1694, a quinazoline antifolate thymidylate synthase inhibitor that is a potent inhibitor of L1210 tumor cell growth in vitro and in vivo: a new agent for clinical study. Cancer Res 1991, 51:5579-5586.
-
(1991)
Cancer Res
, vol.51
, pp. 5579-5586
-
-
Jackman, A.L.1
Taylor, G.A.2
Gibson, W.3
-
5
-
-
0013684729
-
Polyglutamation of the thymidylate synthase inhibitor, ZD 1694 (Tomudex) in normal mouse tissues
-
Jackman AL, Gibson W: Polyglutamation of the thymidylate synthase inhibitor, ZD 1694 (Tomudex) in normal mouse tissues [abstract]. Proc Am Assoc Cancer Res 1995, 36:377.
-
(1995)
Proc Am Assoc Cancer Res
, vol.36
, pp. 377
-
-
Jackman, A.L.1
Gibson, W.2
-
7
-
-
0027378865
-
The duration of the inhibition of thymidylate synthase in intact L1210 cells exposed to different classes of quinazoline analogues
-
Edited by Ayling JE, Nair MG, Baugh CM. New York: Plenum Press
-
Kimbell R, Jackman AL, Boyle FT, et al.: The duration of the inhibition of thymidylate synthase in intact L1210 cells exposed to different classes of quinazoline analogues. In Chemistry and Biology of Pteridines and Folates. Advances in Experimental Medicines and Biology. Edited by Ayling JE, Nair MG, Baugh CM. New York: Plenum Press; 1993, 338:597-600.
-
(1993)
Chemistry and Biology of Pteridines and Folates. Advances in Experimental Medicines and Biology
, vol.338
, pp. 597-600
-
-
Kimbell, R.1
Jackman, A.L.2
Boyle, F.T.3
-
8
-
-
0025744809
-
The pharmacokinetics of the quinazoline antifolate ICI 1694 in mice and rats
-
Jodrell DI, Newell DR, Gibson W, et al.: The pharmacokinetics of the quinazoline antifolate ICI 1694 in mice and rats. Cancer Chemother Pharmacol 1991, 28:331-338.
-
(1991)
Cancer Chemother Pharmacol
, vol.28
, pp. 331-338
-
-
Jodrell, D.I.1
Newell, D.R.2
Gibson, W.3
-
9
-
-
0027889184
-
The history of the development and clinical use of CB3717 and ICI D1694
-
Edited by Ayling JE, Nair MG, Baugh CM. New York: Plenum Press
-
Clarke SJ, Jackman AL, Judson IR: The history of the development and clinical use of CB3717 and ICI D1694. In Chemistry and Biology of Pteridines and Folates. Advances in Experimental Medicines and Biology. Edited by Ayling JE, Nair MG, Baugh CM. New York: Plenum Press; 1993, 339:277-290.
-
(1993)
Chemistry and Biology of Pteridines and Folates. Advances in Experimental Medicines and Biology
, vol.339
, pp. 277-290
-
-
Clarke, S.J.1
Jackman, A.L.2
Judson, I.R.3
-
10
-
-
9244240774
-
Phase I trial of ZD1694, a new folate-based thymidylate synthase inhibitor, in patients with solid tumors
-
Clarke SJ, Hanwell J, de Boer M, et al.: Phase I trial of ZD1694, a new folate-based thymidylate synthase inhibitor, in patients with solid tumors. J Clin Oncol 1996, 14:1495-1503.
-
(1996)
J Clin Oncol
, vol.14
, pp. 1495-1503
-
-
Clarke, S.J.1
Hanwell, J.2
De Boer, M.3
-
11
-
-
0001139165
-
Phase I trial of ZD 1694 (Tomudex), a direct inhibitor of thymidylate synthase
-
abstract 241
-
Sorensen JM, Jordan E, Grem JL, et al.: Phase I trial of ZD 1694 (Tomudex), a direct inhibitor of thymidylate synthase [abstract 241]. Ann Oncol 1994, 5 (suppl 5):132.
-
(1994)
Ann Oncol
, vol.5
, Issue.5 SUPPL.
, pp. 132
-
-
Sorensen, J.M.1
Jordan, E.2
Grem, J.L.3
-
12
-
-
0003323611
-
Pharmacokinetic studies with Tomudex (ZD 1694)
-
abstract 304
-
Judson IR, Aherne GW, Maughan T, et al.: Pharmacokinetic studies with Tomudex (ZD 1694) [abstract 304]. Ann Oncol 1996, 7 (suppl 1):88.
-
(1996)
Ann Oncol
, vol.7
, Issue.1 SUPPL.
, pp. 88
-
-
Judson, I.R.1
Aherne, G.W.2
Maughan, T.3
-
13
-
-
5544237608
-
Final results of a randomised trial comparing 'Tomudex' (raltitrexed) with 5-fluorouracil plus leucovorin in advanced colorectal cancer
-
Cunningham D, Zalcberg JR, Rath U, et al.: Final results of a randomised trial comparing 'Tomudex' (raltitrexed) with 5-fluorouracil plus leucovorin in advanced colorectal cancer. Ann Oncol 1996, 7:961-965.
-
(1996)
Ann Oncol
, vol.7
, pp. 961-965
-
-
Cunningham, D.1
Zalcberg, J.R.2
Rath, U.3
-
14
-
-
0030847327
-
Clinical efficacy of 'Tomudex' (raltitrexed) in advanced colorectal cancer
-
Kerr DJ: Clinical efficacy of 'Tomudex' (raltitrexed) in advanced colorectal cancer. Anticancer Drugs 1997, 8 (suppl 2):S11-S15.
-
(1997)
Anticancer Drugs
, vol.8
, Issue.2 SUPPL.
-
-
Kerr, D.J.1
-
15
-
-
0030823834
-
Overview of the tolerability of 'Tomudex' (raltitrexed): Collective clinical experience in advanced colorectal cancer
-
Zalcberg J: Overview of the tolerability of 'Tomudex' (raltitrexed): collective clinical experience in advanced colorectal cancer. Anticancer Drugs 1997, 8 (suppl 2):S17-S22.
-
(1997)
Anticancer Drugs
, vol.8
, Issue.2 SUPPL.
-
-
Zalcberg, J.1
-
16
-
-
0029931840
-
'Tomudex' (ZD 1694): A novel thymidylate synthase inhibitor with clinical antitumour activity in a range of solid tumours
-
Cunningham D, Zalcberg J, Smith I, et al.: 'Tomudex' (ZD 1694): a novel thymidylate synthase inhibitor with clinical antitumour activity in a range of solid tumours. Ann Oncol 1996, 7:179-182.
-
(1996)
Ann Oncol
, vol.7
, pp. 179-182
-
-
Cunningham, D.1
Zalcberg, J.2
Smith, I.3
|