Exercise-associated hyponatremia in Alaskan sled dogs: Urinary and hormonal responses

Journal of Applied Physiology

Volumn 83, Issue 3, 1997, Pages 824-829

  Hinchcliff, K W ^a   Reinhart, G A ^b   Burr, J R ^b   Swenson, R A ^b  

^a OHIO STATE UNIVERSITY   (United States)

^b NONE

Author keywords

Aldosterone; Arginine vasopressin; Atrial natriuretic peptide; Deuterium; Osmolality; Renin

Indexed keywords

ALDOSTERONE; ARGIPRESSIN; CALCIUM; CHLORIDE ION; CREATININE; POTASSIUM ION; SODIUM ION; UREA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COLD ACCLIMATIZATION; DOG; EXERCISE; FEMALE; HORMONE RESPONSE; HYPONATREMIA; MALE; NONHUMAN; OSMOLALITY; PLASMA RENIN ACTIVITY; PRIORITY JOURNAL; URINARY EXCRETION;

EID: 0030823742     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/jappl.1997.83.3.824     Document Type: Article

References (29)

1. Abramov, M., R. Beauwens, and E. Cogan. Cellular events in vasopressin action. Kidney Int. 2, Suppl. 21: S56-S60, 1987.
2. Burr, J. R., G. A. Reinhart, R. A. Swenson, S. F. Swaim, D. M. Vaughn, and D. M. Bradley. Comparison of biological changes before and after racing, and between dogs competing in long-distance sled dog races. In: Recent Advances in Canine and Feline Nutritional Research, edited by D. P. Carey, S. A. Norton, and S. M. Bolser. Wilmington, OH: Orange Frazer Press, 1996, p. 207.
3. Cardozo, R. H., and I. S. Edelman. The volume of distribution of sodium thiosulfate as a measure of the extracellular fluid space. J. Clin. Invest. 31: 280-290, 1952.
4. Carlson, G. P. Fluid and electrolyte alterations in endurance-trained horses. In: Proc. First Intl. Symp. on Equine Hematology, edited by H. Kitchen and J. D. Krehbiel. East Lansing, MI: Continuing Education Service, Michigan State Univ., 1975, p. 473.
5. Costill, D. L., R. Cote, and W. Fink. Muscle water and electrolytes following varied levels of dehydration in man. J. Appl. Physiol. 40: 6-11, 1976.
6. DiBartola, S. P. Disorders of sodium and water: hypernatremia and hyponatremia. In: Fluid Therapy in Small Animal Practice, edited by S. P. DiBartola. Philadelphia, PA: Saunders, 1992, p. 57-88.
7. Edelman, I. S., J. Leibman, M. P. O'Meara, and L. W. Birkenfeld. Interrelations between serum sodium concentration, serum osmolality and total exchangeable sodium, total exchangeable potassium, and total body water. J. Clin. Invest. 37: 1236-1256, 1958.
8. Ferrus, L., D. Commenges, J. Gire, and P. Varene. Respiratory water loss as a function of ventilatory or environmental factors. Respir. Physiol. 56: 11-20, 1984.
9. Frizzell, R. T., G. H. Lang, D. C. Lowance, and S. R. Lathan. Hyponatremia and ultramarathon running. JAMA 255: 772-774, 1986.
10. Galun, E., I. Tur-Kaspa, E. Assia, R. Berstein, N. Strauss, Y. Epstein, and M. M. Popovtzer. Hyponatremia induced by exercise: a 24-hour endurance march study. Miner. Electrolyte Metab. 17: 315-320, 1991.
11. Hiller, W. D. B. Dehydration and hyponatremia during triathlons. Med. Sci. Sports Exerc. 21: S219-S221, 1989.
12. Hinchcliff, K. W., C. W. Kohn, R. J. Geor, L. A. McCutcheon, J. Foreman, F. Andrews, K. Allen, S. White, L. Williamson, and P. Maykuth. Physiological responses of horses competing in a modified one star three day event. Equine Vet. J. Suppl. 20: 97-104, 1996.
13. Hinchcliff, K. W., G. A. Reinhart, J. R. Burr, C. J. Schreier, and R. A. Swenson. Metabolizable energy intake, total energy expenditure and metabolic scope of Alaskan sled dogs during prolonged exertion (Abstract). FASEB J. 8: A791, 1994.
14. Hinchcliff, K. W., G. A. Reinhart, J. R. Burr, C. J. Schreier, and R. A. Swenson. Effect of racing on serum sodium and potassium concentration and acid: base status of Alaskan sled dogs. J. Am. Vet. Med. Assoc. 210: 1615-1618, 1997.
15. Hoyt, R. W., T. E. Jones, T. P. Stein, G. W. McAninch, H. R. Leiberman, E. W. Askew, and A. Cymerman. Doubly labeled water measurement of human energy expenditure during strenuous exercise. J. Appl. Physiol. 71: 16-22, 1991.
16. Irving, R. A., T. D. Noakes, R. Buck, R. Van Zyl Smit, E. Raine, J. Godlonton and R. J. Norman. Evaluation of renal function and fluid homeostasis during recovery from exercise-induced hyponatremia. J. Appl. Physiol. 70: 342-348, 1991.
17. Irving, R. A., T. D. Noakes, S. C. Burger, K. H. Myburgh, D. Querido, and R. Van Zyl Smit. Plasma volume and renal function during and after ultramarathon running. Med. Sci. Sports Exerc. 22: 581-587, 1990.
18. Kohn, C. W., and S. P. DiBartola. Composition and distribution of body fluids in dogs and cats. In: Small Animal Fluid Therapy, edited by S. P. DiBartola. Philadelphia, PA: Saunders, 1993, p. 1-31.
19. McCutcheon, L. J., R. J. Geor, M. H. Hare, G. L. Ecker, and M. I. Lindinger. Sweating rate and sweat compostion during exercise and recovery in ambient heat and humidity. Equine Vet. J. Suppl. 20: 153-157, 1996.
20. Needle, M. A., G. J. Kaloyanides, and W. B. Schwartz. The effects of selective depletion of hydrochloric acid on acid-base and electrolyte equilibrium. J. Clin. Invest. 43: 1836-1846, 1964.
21. Noakes, T. D. The hyponatremia of exercise. Int. J. Sport Nutr. 2: 205-228, 1992.
22. Rose, R. J., J. E. Ilkiw, D. Sampson, and J. W. Backhouse. Changes in blood gas, acid-base and metabolic parameters in horses during three-day event competition. Res. Vet. Sci. 28: 393-395, 1980.
23. Schott, H. C., K. S. McGlade, H. A. Molander, A. J. Leroux, and M. T. Hines. Body weight, fluid, electrolyte, and hormonal changes in horses competing in 50- and 100-mile endurance rides. Am. J. Vet. Res. 58: 303-309, 1997.
24. Schwartz, W. B., N. C. Brackett, and J. J. Cohen. The response of extracellular hydrogen ion concentration to graded degrees of chronic hypercapnia: the physiologic limits of defense of pH. J. Clin. Invest. 44: 291-301, 1965.
25. Snow, D. H., M. G. Kerr, M. A. Nimmo, and E. M. Abbott. Alterations in blood, sweat, urine, and muscle composition during prolonged exercise in the horse. Vet. Rec. 110: 377-384, 1982.
26. Spraycar, M. Stedman's Medical Dictionary (26th ed.). Baltimore, MD: Williams & Wilkins, 1995, p. 837.
27. Surgenor, S., and R. E. Uphold. Acute hyponatremia in ultra-endurance athletes. Am. J. Emerg. Med. 12: 441-444, 1994.
28. Wolfe, R. R. Radioactive and Stable Isotope Tracers in Biomedicine: Principles and Practice of Kinetic Analysis. New York: Wiley-Liss, 1992, p. 1477.
29. Wong, W. W., L. S. Lee, and P. D. Klein. Deuterium and oxygen-18 measurements on microliter samples of urine, plasma, saliva, and human milk. Am. J. Clin. Nutr. 45: 905-913, 1987.