Basic fibroblast growth factor regulates proliferation and motility of human hepatoma cells by an autocrine mechanism

Journal of Hepatology

Volumn 27, Issue 4, 1997, Pages 677-687

  Kin, Motoaki ^a   Sata, Michio ^a   Ueno, Takato ^a   Torimura, Takuji ^a   Inuzuka, Sadataka ^a   Tsuji, Riko ^a   Sujaku, Kodo ^a   Sakamoto, Masaharu ^a   Sugawara, Hiroshi ^a   Tamaki, Seisyu ^a   Tanikawa, Kyuichi ^a  

^a KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Basic fibroblast growth factor; Fibroblast growth factor receptor l; Hepatocellular carcinoma; Hepatoma cell

Indexed keywords

FIBROBLAST GROWTH FACTOR;

ADULT; AGED; ARTICLE; AUTOCRINE EFFECT; CANCER GROWTH; CLINICAL ARTICLE; CONFOCAL LASER MICROSCOPY; DNA SYNTHESIS; FEMALE; GROWTH REGULATION; HEPATOMA CELL; HUMAN; IMMUNOHISTOCHEMISTRY; LIVER BIOPSY; MALE; PRIORITY JOURNAL; PROTEIN DETERMINATION;

EID: 0030823411     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-8278(97)80085-2     Document Type: Article

References (47)

1. Motoo Y, Sawabu N, Nakanuma Y. Expression of epidermal growth factor and fibroblast growth factor in human hepatocellular carcinoma: an immunohistochemical study. Liver. 11:1991;272-277.
2. Derynck R, Goeddel DV, Ullrich A, Gutterman JU, Williams RD, Bringman TS, et al. Synthesis of messenger RNAs for transforming growth factor α and β and the epidermal growth factor receptor by human tumors. Cancer Res. 47:1987;707-712.
3. Harris L, Preat V, Farber E. Patterns of ligand binding to normal, regenerating, preneoplastic, and neoplastic rat hepatocytes. Cancer REs. 47:1987;3954-3958.
4. Liu C, Tsao MS, Grisham JW. Transforming growth factors produced by normal and neoplastically transformed rat liver epithelial cells in culture. Cancer Res. 48:1988;850-855.
5. Fukusato T, Mori S, Kawamoto T, Taniguchi S, Machinami R. Immunohistochemical and ultrastructural localization of epidermal growth factor receptor in human liver and hepatocellular carcinoma tissues. Acta Pathol Jpn. 40:1990;22-29.
6. Lee LW, Raymond VW, Tsao MS, Lee DC, Earp HS, Grisham JW. Clonal cosegregation of tumorigenicity with overexpression of c-myc and transforming growth factor α genes in chemically transformed rat liver epithelial cells. Cancer Res. 51:1991;5238-5244.
7. Inui Y, Higashiyama S, Kawata S, Tamura S, Miyagawa J, Taniguchi N, et al. Expression of heparin-binding epidermal growth factor in human hepatocellular carcinoma. Gastroenterology. 107:1994;1799-1804.
8. Rifkin D, Moscatelli D. Recent developments in the cell biology of basic fibroblast growth factor. J Cell Biol. 109:1989;1-6.
9. Burgess WH, Maciag T. The heparin-binding (fibroblast) growth factor family of proteins. Annu Rev Biochem. 58:1989;575-606.
10. Neufeld G, Mitchell R, Ponte P, Gospodarowicz D. Expression of human basic fibroblast growth factor cDNA in baby hamster kidney-derived cells results in autonomous cell growth. J Cell Biol. 106:1988;1385-1394.
11. Rogelj S, Weinberg RA, Fanning P, Klagsbrun M. Basic fibroblast growth factor fused to a signal peptide transforms cells. Nature. 331:1988;173-175.
12. Sasada R, Kurokawa T, Iwane M, Igarashi K. Transformation of mouse BALB/c 3T3 cells with human basic fibroblast growth factor cDNA. Mol Cell Biol. 8:1988;588-594.
13. Luqmani YA, Graham M, Coombes RC. Expression of basic fibroblast human breast, and comparison with other normal tissues. Br J Cancer. 66:1992;273-280.
14. Yamaguchi F, Saya H, Bruner JM, Morrison RS. Differential expression of two fibroblast growth factor-receptor genes is associated with malignant progression in human astrocytomas. Proc Natl Acad Sci USA. 91:1994;484-488.
15. Yamanaka Y, Friess H, Bunchler M, Berger HG, Uchida E, Onda M, et al. Overexpression of acidic and basic fibroblast growth factors in human pancreatic cancer correlates with advanced tumor stage. Cancer Res. 53:1993;5289-5296.
16. Kobrin MS, Yamanaka Y, Friess H, Lopez ME, Korc M. Aberrant expression of type 1 fibroblast growth factor receptor in human pancreatic adenocarcinomas. Cancer Res. 53:1993;4741-4744.
17. Johnson DE, Williams LT. Structural and functional diversity in the FGF receptor multigene family. Adv Cancer Res. 60:1993;1-41.
18. Shi E, Kan M, Xu J, Wang F, Hou J, McKeehan WL. Control of fibroblast growth factor receptor kinase signal transduction by heterodimerization of combinatorial splice variants. Mol Cell Biol. 13:1993;3907-3918.
19. Lobb R, Sasse J, Sullivan R, Shing Y, D'Amore P, Jacobs J, et al. Purification and characterization of heparin-binding endothelial cell growth factors. J Biol Chem. 261:1986;1924-1928.
20. Klagsbrun M, Sasse J, Sullivan R, Smith JA. Human tumor cells synthesize an endothelial cell growth factor that is structurally related to basic fibroblast growth factor. Proc Natl Acad Sci USA. 83:1986;2448-2452.
21. Shimoyama Y, Gotoh M, Ino Y, Sakamoto M, Kato K, Hirohashi S. Characterization of high-molecular-mass forms of basic fibroblast growth factor produced by hepatocellular carcinoma cells: possible involvement of basic fibroblast growth factor in hepatocarcinogenesis. Jpn J Cancer Res. 82:1991;1263-1270.
22. Nicolson GL. Organ specificity of tumor metastasis: role of preferential adhesion, invasion and growth of malignant cells at specific secondary sites. Cancer Metastasis Rev. 7:1988;143-188.
23. Raz A, Ben-Ze'ev A. Cell-contact and -architecture of malignant cell and their relationship to metastasis. Cancer Metastasis Rev. 6:1987;3-21.
24. Gibson JB, Sobin LH. Histological typing of tumors of the liver, biliary tract and pancreas. International Histological Classification of Tumors. 1978;19-25 World Health Organization, Geneva.
25. Edmondson HA, Steiner PE. Primary carcinoma of the liver: a study of 100 cases among 48,900 necropsies. Cancer. 7:1954;462-503.
26. Abraham JA, Whang JL, Tumolo A, Mergia A, Friedman J, Gospodarowicz D, et al. Human basic fibroblast growth factor: nucleotide sequence and genomic organization. EMBO. 5:1986;2523-2528.
27. Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidium thiocynate-phenol-chloroform extraction. Anal Biochem. 162:1987;156-159.
28. Zhao XM, First WH, Yeoh TK, Miller GG. Modification of alternative messenger RNA splicing of fibroblast growth factor receptors in human cardiac allografts during rejection. J Clin Invest. 94:1994;992-1003.
29. Albrecht-Buehler G. The phagokinetic tracks of 3T3 cells. Cell. 11:1977;359-404.
30. Hasegawa Y, Takada M, Yamamoto M, Saitoh Y. The gradient of basic fibroblast growth factor concentration in human pancreatic cancer cell invasion. Biochem Biophys Res Commun. 200:1994;1435-1439.
31. Lynch RM, Fogarty KE, Fay FS. Modulation of hexokinase association with mitochondria analyzed with quantitative three-dimensional confocal microscopy. J Cell Biol. 112:1991;385-395.
32. Sporn MB, Roberts AB. Autocrine growth factors and cancer. Nature. 313:1985;745-747.
33. Stoscheck CM, King LE Jr. Role of epidermal growth factor in carcinogenesis. Cancer Res. 46:1986;1030-1037.
34. Sporn MB, Roberts AB. Autocrine secretion - 10 years later. Ann Intern Med. 117:1992;408-414.
35. Gross JL, Herblin WF, Dusak BA, Czerniak P, Diamond MD, Sun T, et al. Effects of modulation of basic fibroblast growth factor on tumor growth in vivo. J Natl Cancer Inst. 85:1993;121-131.
36. New BA, Yeoman LC. Identification of basic fibroblast growth factor sensitivity and receptor and ligand expression in human colon tumor cell lines. J Cell Physiol. 150:1992;320-326.
37. Mira-y-Lopez R, Joseph-Silverstein J, Rifkin DB, Ossowski L. Identification of a pituitary factor responsible for enhancement of plasminogen activator activity in breast tumor cells. Proc Natl Acad Sci USA. 83:1986;7780-7784.
38. Horikawa T, Norris DA, Yohn JJ, Zekman T, Travers JB, Morelli JG. Melanocyte mitogens induce both melanocyte chemokinesis and chemotaxis. J Invest Dermatol. 104:1995;256-259.
39. Hawker JR Jr, Granger HJ. Internalized basic fibroblast growth factor translocates to nuclei of venular endothelial cells. Am J Physiol. 262:1992;1525-1537.
40. Nakanishi Y, Kihara K, Mizuno K, Masamune Y, Yoshitake Y, Nishikawa K. Direct effect of basic fibroblast growth factor on gene transcription in a cell-free system. Proc Natl Acad Sci USA. 89:1992;5216-5220.
41. Kaipainen A, Vlaykova T, Hatva E, Böhling T, Jekunen A, Pyrhönen S, et al. Enhanced expression of the Tie receptor tyrosine kinase messenger RNA in the vascular endothelium of metastatic melanomas. Cancer Res. 54:1994;6571-6577.
42. Plate KH, Breier G, Weich HA, Risau W. Vascular endothelial growth factor is a potential tumor angiogenesis factor in human gliomas in vivo. Nature. 359:1992;845-848.
43. Brown LF, Berse B, Jackman RW, Tognazzi K, Guidi AJ, Dvorak HF, et al. Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in breast cancer. Hum Pathol. 26:1995;86-91.
44. Hatva E, Kaipainen A, Mentula P, Jääskeläinen J, Paetau A, Haltia M, et al. Expression of endothelial cell-specific receptor tyrosine kinases and growth factors in human brain tumors. Am J Pathol. 146:1995;368-378.
45. Connolly DT, Olander JV, Heuvelman D, Nelson R, Monsell R, Siegel N, et al. Human vascular permeability factor. J Biol Chem. 264:1989;20017-20024.
46. Shweiki D, Itin A, Soffer D, Keshet E. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature. 359:1992;843-845.
47. Lee G-H, Merlino G, Fausto N. Development of liver tumors in transforming growth factor in transgenic mice. Cancer Res. 52:1992;5162-5170.