Induction of interleukin-6 (Il-6) autoantibodies through vaccination with an engineered il-6 receptor antagonist

Nature Biotechnology

Volumn 15, Issue 10, 1997, Pages 997-1001

  Ciapponi, Laura ^a   Maione, Domenico ^a   Scoumanne, Ariane ^a   Costa, Patrizia ^a   Hansen, Morten Bagge ^a,b   Svenson, Morten ^a,b   Bendtzen, Klaus ^a,b   Alonzi, Tonino ^a   Paonessa, Giacomo ^a   Cortese, Riccardo ^a   Ciliberto, Gennaro ^a   Savino, Rocco ^a  

^a IRBM   (Italy)

^b Rigshospitalet   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR; MONOCLONAL ANTIBODY;

ACTIVE IMMUNIZATION; ANIMAL EXPERIMENT; ANTIBODY SPECIFICITY; ANTIGEN BINDING; ARTICLE; AUTOIMMUNITY; CONTINUOUS INFUSION; DRUG DELIVERY SYSTEM; DRUG SYNTHESIS; GENETIC ENGINEERING; IMMUNOREGULATION; IMMUNOSTIMULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSGENIC MOUSE;

ALUMINUM HYDROXIDE; ANIMALS; ANTIGEN-ANTIBODY REACTIONS; AUTOANTIBODIES; BINDING SITES; CROSS REACTIONS; ENZYME-LINKED IMMUNOSORBENT ASSAY; ESCHERICHIA COLI; GENE EXPRESSION REGULATION; GENETIC ENGINEERING; HUMANS; INJECTIONS, INTRAPERITONEAL; INTERLEUKIN-6; MICE; MICE, TRANSGENIC; RECEPTORS, INTERLEUKIN-6; RECOMBINANT PROTEINS; VACCINATION;

ANIMALIA; MUS MUSCULUS;

EID: 0030823269     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt1097-997     Document Type: Article

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