Mechanisms of amiloride stimulation of Mg2+ uptake in immortalized mouse distal convoluted tubule cells

American Journal of Physiology - Renal Physiology

Volumn 272, Issue 2 41-2, 1997, Pages

  Dai, Long Jun ^b   Raymond, Lynn ^b   Friedman, Peter A ^b   Quamme, Gary A ^a  

^a VANCOUVER GENERAL HOSPITAL   (Canada)

^b NONE

Author keywords

Amiloride; Fluorescence; Intracellular free magnesium ion concentration; Mag fura 2; Membrane voltage

Indexed keywords

AMILORIDE; MAGNESIUM ION; NITRENDIPINE; VALINOMYCIN;

ANIMAL CELL; APICAL MEMBRANE; ARTICLE; CELL IMMORTALIZATION; CONCENTRATION RESPONSE; ELECTROLYTE TRANSPORT; FLUORESCENCE; HENLE LOOP; HYPERPOLARIZATION; KIDNEY DISTAL TUBULE; MACULA DENSA; MEMBRANE POTENTIAL; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 0030822559     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.1997.272.2.f249     Document Type: Article

References (34)

1. Allen, G. G., and L. J. Barratt. Origin of positive transepithelial potential difference in early distal segments of rat kidney. Kidney Int. 27: 622-629, 1985.
2. Alon, U., L. S. Costanzo, and J. C. Chan. Additive hypocalciuric effects of amiloride and hydrochlorothiazide in patients treated with calcitriol. Miner. Electrolyte Metab. 10: 379-386, 1984.
3. Banratt, L. J. The effect of amiloride on the transepithelial potential difference of the distal tubule of the rat kidney. Pfluegers Arch. 361: 251-254, 1976.
4. Bundy, J. T., D. Connito, M. D. Mahoney, and P. J. Pontier. Treatment of idiopathic renal magnesium wasting with amiloride. Am. J. Nephrol. 15: 75-77, 1995.
5. Costanzo, L. S. Comparison of calcium and sodium transport in early and late rat distal tubules: effect of amiloride. Am. J. Physiol. 246 (Renal Fluid Electrolyte Physiol. 15): F937-F945, 1984.
6. Costanzo, L. S. Localization of diuretic action in microperfused rat distal tubules: Ca and Na transport. Am. J. Physiol. 248 (Renal Fluid Electrolyte Physiol. 17): FS27-F535, 1985.
7. Costanzo, L. S., and I. M. Weiner. Relationship between clearances of Ca and Na: effect of distal diuretics and PTH. Am. J. Physiol. 230: 67-73, 1976.
8. Costanzo, L. S., and E. E. Windhager. Calcium and sodium transport by the distal convoluted tubule of the rat. Am. J. Physiol. 235 (Renal Fluid Electrolyte Physiol. 4): F492-F506, 1978.
9. 2+ and magnesium depletion in isolated renal thick ascending limb cells. J. Clin. Invest. 88: 1255-1264, 1991.
10. Devane, J., and M. P. Ryan. Evidence for a magnesium-sparing action by amiloride diuretic renal clearance studies in rats. Br. J. Pharmacol. 79: 891-896, 1983.
11. Due, C., N. Farman, C. M. Canessa, J. P. Bonvalet, and B. C. Rossier. Cell-specific expression of epithelial sodium channel alpha, beta, and gamma subunits in aldosterone-responsive epithelial from the rat: colocalization by in situ hybridization and immunocytochemistry. J. Cell Biol. 127: 1907-1921, 1994.
12. + transporting targets. Kidney Int. 32: 785-793, 1987.
13. Friedman, P. A., and F. A. Gesek. Stimulation of calcium transport by amiloride in mouse distal convoluted tubule cells. Kidney Int. 48: 1427-1434, 1995.
14. Gesek, F. A., and P. A. Friedman. Mechanism of calcium transport stimulated by chlorothiazide in mouse distal convoluted tubule cells. J. Clin. Invest. 90: 429-438, 1992.
15. Gesek, F. A., and P. A. Friedman. Sodium entry mechanisms in distal convoluted tubule cells. Am. J. Physiol. 268 (Renal Fluid Electrolyte Physiol. 37): F89-F98, 1995.
16. Kroenke, K., D. R. Woods, and J. F. Hanley. The value of serum magnesium determination in hypertensive patients receiving diuretics. Arch. Int. Med. 147: 1553-1556, 1987.
17. Madsen, K. M., and C. C. Tisher. Structure-functional relationships along the distal nephron. Am. J. Physiol. 250 (Renal Fluid Electrolyte Physiol. 19): F1-F15, 1986.
18. 2+ channels sensitive to dihydropyridines and activated by hyperpolarizing voltages. Am. J. Physiol. 267 (Cell Physiol. 36): C157-C165, 1994.
19. Martin, B. J., and K. Milligan. Diuretic-associated hypomagnesuria in the elderly. Arch. Int. Med. 147: 1768-1771, 1987.
20. Merot, J., M. Bidet, B. Gachot, S. Le Maout, N. Koechlin, M. Taue, and P. Poujeol. Electrical properties of rabbit early distal convoluted tubule in primary culture. Am. J. Physiol. 257 (Renal Fluid Electrolyte Physiol. 26): F288-F299, 1989.
21. Murdoch, D. C., G. Forrest, D. L. Davies, and G. T. McInnes. A comparison of the potassium and magnesium-sparing properties of amiloride and spironolactone in diuretic-treated normal subjects. Br. J. Clin. Pharmacol. 35: 373-378, 1993.
22. Obermüller, N., P. Berstein, H. Velázquez, R. Reilly, D. Moser, D. H. Ellison, and S. Bachmann. Expression of the thiazide-sensitive Na-Cl cotransporter in rat and human kidney. Am. J. Physiol. 269 (Renal Fluid Electrolyte Physiol. 38): F900-F910, 1995.
23. Pizzonia, J. H., F. A. Gesek, S. M. Kennedy, B. A. Coutermarsh, B. J. Bacskai, and P. A. Friedman. Immunomagnetic separation, primary culture and characterization of cortical thick ascending limb plus distal convoluted tubule cells from mouse kidney. In Vitro Cell. Dev. Biol. 27A: 409-416, 1991.
24. Quamme, G. A. Effect of furosemide on calcium and magnesium transport in the rat nephron. Am. J. Physiol. 241 (Renal Fluid Electrolyte Physiol. 10): F340-F347, 1981.
25. 2+ in MDCK cells. Am. J. Physiol. 259 (Cell Physiol. 28): C521-C525, 1990.
26. Quamme, G. A., and J. H. Dirks. Effect of intraluminal and contraluminal magnesium and calcium transport in the rat nephron. Am. J. Physiol. 238 (Renal Fluid Electrolyte Physiol. 7): F187-F198, 1980.
27. Richards, F. J. A flexible growth function for empical use. J. Exp. Bot. 10: 290-300, 1959.
28. Rouffignac de, C., and G. A. Quamme. Renal magnesium handling and its hormonal control. Physiol. Rev. 74: 305-322, 1994.
29. Shafik, I. M., and G. A. Quamme. Early adaptation of renal magnesium reabsorption in response to magnesium restriction. Am. J. Physiol. 257 (Renal Fluid Electrolyte Physiol. 26): F974-F977, 1989.
30. Shimizu, T., M. Nakamura, K. Yoshitomi, and M. Imai. Interaction of trichlormethiazide or amiloride with PTH in stimulating calcium absorption in the rabbit connecting tubule. Am. J. Physiol. 261 (Renal Fluid Electrolyte Physiol. 30): F36-F43,1991.
31. Shimizu, T., K. Yoshitomi, M. Nakamura, and M. Imai. Site and mechanisms of action of trichlormethiazide in rabbit distal nephron segments. J. Clin. Invest. 82: 721-730, 1988.
32. Wester, P. O. Electrolyte balance in heart failure and the role for magnesium ions. Am. J. Cardiol. 70: 44C-49C, 1992.
33. Whang, R. Magnesium deficiency: pathogenesis, prevalance, and clinical implications. Am. J. Med. 82: 24-29, 1987.
34. Yoshitomi, K., T. Shimizu, J. Taniguchi, and M. Imai. Electrophysiological characterization of rabbit distal convoluted tubule cell. Pfluegers Arch. 414: 457-463, 1989.