Proteoglycans: The 'Teflon' of the airways?

Thorax

Volumn 52, Issue 10, 1997, Pages 924-925

  Page, C P ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Airway remodelling; Airways inflammation; Asthma; Cell adhesion; Heparin; Proteoglycans

Indexed keywords

CHONDROITIN 4 SULFATE; CHONDROITIN 6 SULFATE; DERMATAN SULFATE; HEPARAN SULFATE; HEPARIN; HISTAMINE; HYALURONIC ACID; PROTEOGLYCAN;

AIRWAY; ASTHMA; BASEMENT MEMBRANE; BRONCHOSPASM; CELL ADHESION; CELL SURFACE; EOSINOPHIL; INFLAMMATION; MAST CELL; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SHORT SURVEY;

EID: 0030822365     PISSN: 00406376     EISSN: None     Source Type: Journal    
DOI: 10.1136/thx.52.10.924     Document Type: Short Survey

References (12)

1. Tyrrell D, Kilfeather S, Page CP. Therapeutic use of heparin beyond its traditional role as an anti-coagulant. Trends Pharmacol Sci 1995;293:369 76.
2. Willenborg DO, Parish CR. Inhibition of allergic encephalomyelitis in rats by treatment with sulphated polysaccharides. J Immunol 1988;140:3401 5.
3. Gorski A, Wasik M, Nowaczyk M, Korczak-Kowalska G. Immunomodulating activity of heparin. FASEB J 1991;5:2287-91.
4. Gaffney PR, Doyle CT, Gafney A, Hogan J, Haves DP, Annis P. Paradoxical response to heparin in ten patients with ulcerative colitis. Am J Gastroenterol 1995;90:220 3
5. Green WF, Konnoris K, Woolcock AJ. Effect of salbutamol, feneterol, and sodium cromoglycate on the release of heparin from sensitized human lung fragments challenged with Dermatophagoides pteronyssinus allergen. Am J Respir Cell Med Biol 1993;8:518-51
6. Lasser EC, Simon RA, Lyon SG, Hamblin AW, Stein R. Heparin-like anticoagulants in asthma. Allergy, 1987;42:619-25.
7. Van der Carr FR, Williams OB. Further studies on the influence of heparin on anaphylactic shock in the guinea-pig. J Immunol 1928;15:13-20.
8. Bowler SD, Smith SM, Lavercombe PS. Heparin inhibits the immediate response to antigen in the skin and lungs of allergic subjects. Am Rev Respir Dis 1993;147:160 3.
9. Diamant Z, Page CP, Hiemstra PS, Van der Meer FJM, Sterk PJ. The effect of inhaled heparin on allergen-induced airway responses and airway inflammation in atopic asthmatics. Am J Respir Crit Care Med 1996;153:1790-5.
10. Seeds EAM, Horne AP, Tyrrell DJ, Page CP. The effect of inhaled heparin and related glycosaminoglycans on allergen-induced eosinophil infiltration in guinea-pigs. Pulm Pharmacol 1995;8:97-105.
11. Ahmed T, Garrigo J, Danta I. Preventing bronchoconstriction in exercise-induced asthma with inhaled heparin. N Engl J Med 1993;329:90-5.
12. Crimi N, Armato F, Lamicela M, Magri S, Pistorio MP, Mastruzzo C, et al. Inhibitory effect of heparin on eosinophil recruitment after nasal allergen challenge. Eur Respir J 1995;8:10S.