The effects of prenatally administered endogenous cannabinoid on rat offspring

Pharmacology Biochemistry and Behavior

Volumn 58, Issue 2, 1997, Pages 537-544

  Wenger, T ^a   Fragkakis, G ^a   Giannikou, P ^a   Yiannikakis, N ^a  

^a SEMMELWEIS UNIVERSITY OF MEDICINE   (Hungary)

Author keywords

ANA; Anandamide; Hypothalamo pituitary system; Offspring; Prenatal; Rat

Indexed keywords

ANANDAMIDE; DRONABINOL; FOLLITROPIN; GONADORELIN; GROWTH HORMONE; LUTEINIZING HORMONE; PROLACTIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; FEMALE; HYPOTHALAMUS HYPOPHYSIS SYSTEM; INTRAPERITONEAL DRUG ADMINISTRATION; NONHUMAN; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; RAT;

AGE FACTORS; ANIMALS; ARACHIDONIC ACIDS; BODY WEIGHT; CANNABINOIDS; FEMALE; HYPOTHALAMUS; MALE; MATERNAL EXPOSURE; PITUITARY GLAND; POLYUNSATURATED ALKAMIDES; RATS; RATS, SPRAGUE-DAWLEY; SEX FACTORS; TETRAHYDROCANNABINOL;

ANIMALIA;

EID: 0030821742     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-3057(97)00250-5     Document Type: Article

References (30)

1. Adams I. B., Ryan W., Singer M., Razdan R. K., Compton D. R., Martin B. R. Pharmacological and behavioral evaluation of alkylated anandamide analogs. Life Sci. 56:1995;2041-2048.
2. Childers S. R., Sexton T., Roy M. B. Effects of anandamide on cannabinoid receptors in rat brain membranes. Biochem. Pharmacol. 47:1994;711-715.
3. Dalterio S., Steger R., Mayfield D., Bartke A. Early cannabinoid exposure influences neuroendocrine and reproductive functions in mice. II Postnatal effects. Pharmacol. Biochem. Behav. 20:1984;115-123.
4. Devane W. A., Axelrod J. Enzymatic synthesis of anandamide, an endogenous ligand for the cannabinoid receptor by brain membranes. Proc. Natl. Acad. Sci. USA. 91:1994;6698-6701.
5. Devane W. A., Hanus L., Beuer A., Pertwee R. G., Stevenson L. A., Griffin G., Gibson D., Mandelbaum A., Etinger A., Mechoulam R. Isolation and structure of a brain constituent that binds to cannabinoid receptor. Science. 258:1992;1946-1949.
6. Di-Marzo V., Fontana A., Cadas H., Schinelli S., Cimino G., Schwartz J. C., Pionelli D. Formation and inactivation of endogenous cannabinoid, anandamide in central neurons. Nature. 372:1994;686-691.
7. Falkenstein B. A., Halley D. C. Effect of acute intravenous administration of delta-9-tetrahydrocannabinol on the episodic secretion of immunoassayable growth hormone in the rat. Life Sci. 50:1992;1109-1116.
8. Fernandez-Ruiz J. J., Rodriguez de Fonseca F., Navarro M., Ramos J. A. Maternal cannabinoid exposure and brain development. Changes in the ontogeny of dopaminergic neurons Murphy L., Bartke A. Marijuana/cannabinoids. 1992;119-164 CRC Press, Boca Raton, FL.
9. Friede E., Mechoulam R. Pharmacological activity of the cannabinoid receptor agonist, anandamide, a brain constituent. Eur. J. Pharmacol. 231:1993;313-314.
10. Herkenham M. Localization of cannabinoid receptors in brain and periphery. Pertwee R. G. Cannabinoid receptors. 1995;145-166 Academic Press, London/San Diego.
11. Howlett A. C., Evans D. M., Houston D. B. The cannabinoid receptor. Murphy L., Bartke A. Marijuana/cannabinoids. 1992;35-72 CRC Press, Boca Raton, FL.
12. Hutchings D. E., Morgan B., Brake S. C., Shi T., Lasalle E. Delta-9-tetrahydrocannabinol during pregnancy in rat. I Differential effects of maternal nutrition, embryo toxicity and growth in the offspring. Neurotoxicol. Teratol. 9:1987;39-43.
13. Matsuda L. A., Lolait S. J., Brownstein M. G., Goung A. C., Bonner T. I. Structure of a cannabinoid receptor and functional expression of the cloned cDNA. Nature. 346:1990;561-564.
14. McLaughin C. R., Abood M. E. Developmental expression of cannabinoid receptor mRNA. Brain Res. Dev. 76:1993;75-78.
15. Mechoulam R. Marihuana chemistry. Science. 169:1970;1159-1166.
16. Mizunuma H., Samson W. K., Lumpkin M. D., Moltz J. H., Fawcett C. A., McCann S. M. Purification of a bioactive FSH-releasing factor (FSHRF). Brain Res. Bull. 10:1983;623-629.
17. Nathanielsz P. W. Endocrine mechanisms of parturition. Annu. Rev. Physiol. 40:1978;411-445.
18. Paria B. C., Das S. K., Dey S. K. The preimplantation mouse embryo is a target for cannabinoid ligand-receptor signaling. Proc. Natl. Acad. Sci. USA. 92:1995;9460-9464.
19. Pertwee R. G. Pharmacological, physiological and clinical implications of the discovery of cannabinoid receptors. An overview Pertwee R. G. Cannabinoid receptors. 1995;1-34 Academic Press, London/San Diego.
20. Pertwee R. G., Griffin G., Hanus L., Mechoulam R. Effects of two endogenous fatty acid ethanolamides on mouse vasa deferentia. Eur. J. Pharmacol. 259:1994;115-120.
21. Rettori V., Wenger T., Snyder G., Dalterio S., McCann S. M. Hypothalamic action of delta-9-tetrahydrocannabinol to inhibit the release of prolactin and growth hormone in the rat. Neuroendocrinology. 47:1988;498-503.
22. Smith C. G. Effects of marijuana on neuroendocrine function. NIDA Res. Monogr. 31:1980;120-142.
23. Smith C. G., Besch N. F., Asch R. H. Effects of marijuana on the reproductive system. Thomas J. A., Shingal R. Advances in sex hormone research. 1980;273-294 Urban and Swarzenberg, Baltimore.
24. Smith P. B., Compton D. R., Welch S. P., Razdan R. K., Mechoulam R., Martin B. R. The pharmacological activity of anandamide, a putative endogenous cannabinoid in mice. J. Pharmacol. Exp. Ther. 270:1994;219-227.
25. 3H] 11-OH delta-9-THC-DMH. J. Pharmacol. Exp. Ther. 263:1992;1383-1390.
26. Wenger T., Croix D., Tramu G. Marihuana and pregnancy. Dohler K. H., Pawlikowski M. Progress in neuropeptide research. 1988;111-119 Birkhauser Verlag, Basel.
27. Wenger T., Croix D., Tramu G., Leonardelli J. Prenatally administered delta-9-tetrahydrocannabinol temporarily inhibits the developing hypothalamo-pituitary system in rats. Pharmacol. Biochem. Behav. 40:1991;599-602.
28. 9-tetrahydrocannabinol on pregnancy, puberty and the neuroendocrine system. Murphy L., Bartke A. Marijuana/cannabinoids. 1992;539-560 CRC Press, Boca Raton, FL.
29. Wenger T., Leonardelli J. Circadian and cyclic LHRH variations in the organum vasculosum of the lamina terminalis of female and male rats. Neuroendocrinology. 31:1980;331-337.
30. Wiedenfeld S., Feldman S., Mechoulam R. Effect of the brain constituent, anandamide, a cannabinoid receptor agonist on the hypothalamo-pituitary-adrenal axis in the rat. Neuroendocrinology. 59:1994;110-112.