Efficacy of aminosidine administered alone or in combination with meglumine antimoniate for the treatment of experimental visceral leishmaniasis caused by Leishmania infantum

Journal of Antimicrobial Chemotherapy

Volumn 40, Issue 2, 1997, Pages 287-289

  Gangneux, Jean Pierre ^a   Sulahian, Annie ^a   Garin, Yves Jean François ^a   Derouin, Francis ^a  

^a UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; ANTIPROTOZOAL AGENT; MEGLUMINE ANTIMONATE; PAROMOMYCIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; EXPERIMENTAL INFECTION; LEISHMANIA INFANTUM; LIVER; MOUSE; NONHUMAN; SPLEEN; VISCERAL LEISHMANIASIS;

ANIMALS; ANTIPROTOZOAL AGENTS; DISEASE MODELS, ANIMAL; DRUG THERAPY, COMBINATION; FEMALE; LEISHMANIA INFANTUM; LEISHMANIASIS, VISCERAL; LIVER; MEGLUMINE; MICE; MICE, INBRED BALB C; ORGANOMETALLIC COMPOUNDS; PAROMOMYCIN; SPLEEN;

EID: 0030821714     PISSN: 03057453     EISSN: None     Source Type: Journal    
DOI: 10.1093/jac/40.2.287     Document Type: Article

References (10)

1. Neal, R. A., Allen, S., McCoy, N., Olliaro, P. & Croft, S. L. (1995). The sensitivity of Leishmania species to aminosidine. Journal of Antimicrobial Chemotherapy 35, 577-84.
2. Thakur, C. P., Bhowmick, S., Dolfi, L. & Olliaro, P. (1995). Aminosidine plus sodium stibogluconate for the treatment of Indian kala-azar: a randomized dose-finding clinical trial. Transactions of the Royal Society of Tropical Medicine and Hygiene 89, 219-23.
3. Seaman, J., Pryce, D., Sondorp, H. E., Moody, A., Bryceson, A. D. M. & Davidson, R. N. (1993). Epidemic visceral leishmaniasis in Sudan: a randomized trial of aminosidine plus sodium stibogluconate versus sodium stibogluconate alone. Journal of Infectious Diseases 168, 715-20.
4. Scott, J. A. G., Davidson, R. N., Moody, A. H., Grant, H. R., Felmingham, D., Scott, G. M. S. et al. (1992). Aminosidine (paromomycin) in the treatment of leishmaniasis imported into the United Kingdom. Transactions of the Royal Society of Tropical Medicine and Hygiene 86, 617-19.
5. Dereure, J., Reynes, J., Pratlong, F., Lamaury, I., Rioux, J. A., Janbon, F. et al. (1995). Visceral leishmaniasis in HIV-infected patients in the south of France. Bulletin of the World Health Organization 73, 245-6.
6. Alvar, J., Gutierrez-Solar, B., Molina, R., Lopez-Velez, R., Garcia-Camacho, A., Martinez, P. et al. (1992). Prevalence of Leishmania infection among AIDS patients. Lancet 339, 1427.
7. Davidson, R. N. & Russo, R. (1994). Relapse of visceral leishmaniasis in patients who were coinfected with human immunodeficiency virus and who received treatment with liposomal amphotericin B. Clinical Infectious Diseases 19, 560.
8. Buffet, P. A., Sulahian, A., Garin, Y. J. F., Nassar, N. & Derouin, F. (1995). Culture microtitration: a sensitive method for quantifying Leishmania infantum in tissues of infected mice. Antimicrobial Agents and Chemotherapy 39, 2167-8.
9. Gangneux, J. P., Sulahian, A., Garin, Y. J. F., Farinotti, R. & Derouin, F. (1996). Therapy of visceral leishmaniasis due to Leishmania infantum: experimental assessment of the efficacy of AmBisome. Antimicrobial Agents and Chemotherapy 40, 1214-8.
10. Gangneux, J. P., Sulahian, A., Garin, Y. J. F. & Derouin, F. (1996). Lipid formulations of amphotericin B in the treatment of experimental visceral leishmaniasis due to Leishmania infantum. Transactions of the Royal Society of Tropical Medicine and Hygiene 90, 574-7.