Polychlorinated dibenzo-p-dioxin and dibenzofuran levels and patterns in polyvinylchloride and chloralkali industry workers

International Archives of Occupational and Environmental Health

Volumn 70, Issue 1, 1997, Pages 51-56

  Hansson, Marianne ^a   Barregård, Lars ^b   Sällsten, Gerd ^b   Svensson, B G ^c   Rappe, Christoffer ^a  

^a UMEÅ UNIVERSITY   (Sweden)

^b SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^c LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Chloralkali industry; Occupational exposure; Polychlorinated dibenzo p dioxins; Polychlorinated dibenzofurans; PVC industry

Indexed keywords

CHLORINE; POLYCHLORINATED DIBENZODIOXIN; POLYCHLORINATED DIBENZOFURAN; VINYL CHLORIDE;

ADULT; ARTICLE; BIOACCUMULATION; BIOLOGICAL MONITORING; BLOOD SAMPLING; CONTROLLED STUDY; GAS CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; INDUSTRY; MASS SPECTROMETRY; NORMAL HUMAN; OCCUPATIONAL EXPOSURE; OCCUPATIONAL HEALTH; PRINCIPAL COMPONENT ANALYSIS; WORK ENVIRONMENT;

ANIMALS; BENZOFURANS; CHEMICAL INDUSTRY; CHLORINE; DIET; FISHES; HUMANS; MALE; OCCUPATIONAL EXPOSURE; POLYVINYL CHLORIDE; SWEDEN; TETRACHLORODIBENZODIOXIN;

EID: 0030821394     PISSN: 03400131     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004200050185     Document Type: Article

References (25)

1. Ahlborg UG, Brouwer A, Fingerhut MA, Jacobsen JL, Jacobsen SW, Kennedy SW, et al. (1992) Impact of polychlorinated dibenzo-p-dioxins, dibenzofurans and biphenyls on human and environmental health, with special emphasis on application of toxic equivalency factor concept. Eur J Pharmacol 228:179-199
2. Evers E, Berghem J van, Olie K (1989) Exploratory data analysis of PCDD and PCDF measurements in sediments from industrialised areas. Chemosphere 19:459-466
3. Evers E, Klamer H, Laane R, Govers H (1993) Polychlorinated dibenzo-p-dioxins and dibenzofuran residues in estuarine and coastal North Sea sediments: sources and distribution. Environ Tox Chem 12:1583-1598
4. Hansson M, Grimstad T, Rappe C (1995) Occupational exposure to polychlorinated dibenzo-p-dioxins and dibenzofurans in a magnesium production plant. Occup Environ Med 52:823-826
5. Johansson E, Wold S (1984) Minimising effects of closure on analytical data. Anal Chem 56:1685-1688
6. Littorin M, Hansson M, Rappe C, Kogevinas M (1994) Dioxins in blood from Swedish phenoxy herbicide workers. Lancet 344:611-612
7. Miller A (1993) Dioxin emissions from EDC/VCM plants. Environ Sci Technol 27:1015-1016
8. Neuberger M, Landvoigt W, Derntl F (1991) Blood levels of 2,3,7,8-tetrachlorodibenzo-p-dioxin in chemical workers after chloracne and in comparison groups. Int Arch Occup Environ Health 63:325-327
9. Nygren M, Hansson M, Sjöström M, Rappe C, Kahn P, Gochfeld M, et al. (1988) Development and validation of a method for determination of PCDDs and PCDFs in human blood plasma. Chemosphere 17:1663-1693
10. Oehme M, Bartonova A, Knutzen J (1990) Estimation of polychlorinated dibenzofuran and dibenzo-p-dioxin contamination of a coastal region using isomer profiles in crabs. Environ Sci Technol 24:1836-1841
11. Ott GM, Messerer P, Zober A (1993) Assessment of past occupational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin using blood lipid analyses. Int Arch Occup Environ Health 63:325-327
12. Päpke O, Ball M, Lis A (1992) Various PCDD/PCDF patterns in human blood resulting from different occupational exposures. Chemosphere 25:1101-1108
13. Rappe C (1992) Dietary exposure and human levels of PCDDs and PCDFs. Chemosphere 25:231-234
14. Rappe C (1994) Dioxins, patterns and source identification. Fresenius Z Anal Chem 348:63-75
15. Rappe C, Kjeller L-O, Kulp S-E, Wit C de, Hasselsten I, Palm O (1991) Levels, profile and pattern of PCDDs and PCDFs in samples related to the production and use of chlorine. Chemosphere 23:1629-1636
16. Ryan JJ, Norstrom RJ (1991) Occurrence of polychlorinated dibenzo-p-dioxins and dibenzofurans in humans and major exposure assessment. IARC Sci Publ 108:51-104
17. Safe S (1990) Polychlorinated biphenyls (PCBs), dibenzo-p-dioxins PCDDs, dibenzofurans (PCDFs) and related compounds: environmental and mechanistic considerations which support the development of toxic equivalency factors (TEFs). CRC Crit Rev Toxicol 21: 51-88
18. Stringer RL, Costner P, Johnston PA (1995) PVC manufacture as a source of PCDD/Fs. Organohalogen Compounds 24:119-123
19. Svensson B-G, Nilsson A, Hansson M, Rappe C, Åkesson B, Skerfving S (1991) Exposure of dioxins and dibenzofurans through the consumption of fish. N Engl J Med 324:8-12
20. Svensson B-G, Barregård L, Sällsten G. Nilsson A, Hansson M, Rappe C (1993) Exposure to polychlorinated dioxins (PCDD) and dibenzofurans (PCDF) from graphite electrodes in a chloralkali plant. Chemosphere 27:259-262
21. Vartainen T, Tuomisto J (1994) Jätelietteen aiheuttaman terveysriskin sekä ympäristövaikutusten arviointi (in Finnish) National Public Health Institute, Kupio, Finland
22. WHO (1989) Polychlorinated dibenzo-para-dioxins and dibenzofurans. Environmental health criteria 88. WHO, Geneva
23. WHO (1991) Levels of PCBs, PCDDs and PCDFs in human milk and blood. Second round of quality control studies. Environmental health in Europe 37. WHO, Copenhagen
24. Wold S (1987) Cross-validatory estimation of the number of components in factor and principal components models. Technometrics 20:397-405
25. Wold S, Esbensen K, Geladi P (1987) Principal component analysis. Chemometrics Intel Lab Syst 2:37-52