Suppression of immunoassay results by crossreactivity

Journal of Clinical Ligand Assay

Volumn 20, Issue 2, 1997, Pages 177-179

  Jortani, Saeed A ^a   Miller, James J ^a   Helm, R Allen ^a   Johnson, Nancy A ^a   Valdes Jr , Roland ^a  

^a University of Louisville School of Medicine   (United States)

Author keywords

Crossreactivity; Digoxin; DLIF; Immunoassay; Oleandrin; Suppression

Indexed keywords

DIGITALIS LIKE FACTOR; DIGOXIN;

ARTICLE; CROSS REACTION; FLUOROMETRY; IMMUNOASSAY; RADIOIMMUNOASSAY;

BOVINAE; DIGITALIS;

EID: 0030821203     PISSN: 10811672     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. Miller JJ, Valdes Jr R: Methods for calculating cross-reactivity in immunoassays. J Clin Immunoassay 1992;15:97-107.
2. Valdes Jr R, Miller JJ: Increasing the specificity of immunoassays. J Clin Immunoassay 1992;15:87-96.
3. Matheke ML, Valdes Jr R: Antibody specificity reduces interference by endogenous digoxin-like immunoreactive factors. J Clin Immunoassay 1989;12:115-121.
4. Jortani SA, Miller JJ, Helm RA, et al: Unexpected suppression of digoxin values caused by DLIF. Clin Chem (Abstract) 1996;42:S124.
5. Kanan R, Chan KM, Dietzler DN: Negative interference with Du Pont aca method for measuring digoxin. Clin Chem (letter) 1987;33:446.
6. Qazzaz HMAM, Jortani SA, Poole JM, et al: Evidence for presence of a reduced form of digoxin-like immunoreactive factor (dihydro-DLIF) in mammalian tissues. Clin Chem 1996;42:1092-1099.
7. Shaikh IM, Law BWC, Siegfried BA, et al: Isolation of digoxin-like immunoreactive factors from mammalian adrenal cortex. J Biol Chem 1991;266:13672-13678.