-
1
-
-
0029944106
-
Antitopoisomerase drug action and resistance
-
Nitiss JL, Beck WT. Antitopoisomerase drug action and resistance. Eur J Cancer 1996; 32A: 958-66.
-
(1996)
Eur J Cancer
, vol.32 A
, pp. 958-966
-
-
Nitiss, J.L.1
Beck, W.T.2
-
4
-
-
0028033906
-
Cellular determinants of sensitivity and resistance to topoisomerase inhibitors
-
Pommier Y, Leteurtre F, Fesen MR, et al. Cellular determinants of sensitivity and resistance to topoisomerase inhibitors. Cancer Invest 1994; 12: 530-42.
-
(1994)
Cancer Invest
, vol.12
, pp. 530-542
-
-
Pommier, Y.1
Leteurtre, F.2
Fesen, M.R.3
-
5
-
-
0027292407
-
DNA topoisomerase I and II as targets for rational design of new anticancer drugs
-
Cummings J, Smyth JF. DNA topoisomerase I and II as targets for rational design of new anticancer drugs. Ann Oncol 1993; 4: 533-43.
-
(1993)
Ann Oncol
, vol.4
, pp. 533-543
-
-
Cummings, J.1
Smyth, J.F.2
-
6
-
-
0021017886
-
Novel antitumor agents CI-920, PD 113,270 and PD 113,271. I: Taxonomy, fermentation and biological properties
-
Tunac JB, Graham BD, Dobson WE. Novel antitumor agents CI-920, PD 113,270 and PD 113,271. I: taxonomy, fermentation and biological properties. J Antibiot 1983; 36: 1595-600.
-
(1983)
J Antibiot
, vol.36
, pp. 1595-1600
-
-
Tunac, J.B.1
Graham, B.D.2
Dobson, W.E.3
-
7
-
-
0021017333
-
Novel antitumor agents CI-920, PD 113,270 and PD 113,270. II: Isolation and characterization
-
Stampwala SS, Bunge RH, Hurley TR. Novel antitumor agents CI-920, PD 113,270 and PD 113,270. II: isolation and characterization. J Antibiot 1983; 36: 1601-5.
-
(1983)
J Antibiot
, vol.36
, pp. 1601-1605
-
-
Stampwala, S.S.1
Bunge, R.H.2
Hurley, T.R.3
-
8
-
-
0021998266
-
Novel antitumor agents CI-920, PD 113270 and PD 113271. III: Structure determination
-
Hokanson GC, French JC. Novel antitumor agents CI-920, PD 113270 and PD 113271. III: structure determination. J Org Chem 1985; 50: 462-6.
-
(1985)
J Org Chem
, vol.50
, pp. 462-466
-
-
Hokanson, G.C.1
French, J.C.2
-
9
-
-
0021369459
-
Anticancer activity of the structurally novel antibiotic CI-920 and its analogues
-
Leopold WR, Shillis JL, Mertus AE, Nelson JM, Roberts BJ, Jackson RC. Anticancer activity of the structurally novel antibiotic CI-920 and its analogues. Cancer Res 1984; 44: 1928-32.
-
(1984)
Cancer Res
, vol.44
, pp. 1928-1932
-
-
Leopold, W.R.1
Shillis, J.L.2
Mertus, A.E.3
Nelson, J.M.4
Roberts, B.J.5
Jackson, R.C.6
-
10
-
-
0022330898
-
The biochemical pharmacology of CI-920, a structurally novel antibiotic with antileukemic activity
-
Jackson RC, Fry DW, Boritzki TJ, Roberts BJ, Hook KE, Leopold WR. The biochemical pharmacology of CI-920, a structurally novel antibiotic with antileukemic activity. Adv Enzyme Regul 1985; 23: 193-215.
-
(1985)
Adv Enzyme Regul
, vol.23
, pp. 193-215
-
-
Jackson, R.C.1
Fry, D.W.2
Boritzki, T.J.3
Roberts, B.J.4
Hook, K.E.5
Leopold, W.R.6
-
11
-
-
0021174011
-
Transport of the antitumor antibiotic CI-920 into L1210 leukemia cells by the reduced folate carrier system
-
Fry DW, Besserer JA, Boritzki TJ. Transport of the antitumor antibiotic CI-920 into L1210 leukemia cells by the reduced folate carrier system. Cancer Res 1984; 44: 3366-70.
-
(1984)
Cancer Res
, vol.44
, pp. 3366-3370
-
-
Fry, D.W.1
Besserer, J.A.2
Boritzki, T.J.3
-
12
-
-
0023024240
-
Antimycotic effects of the novel antitumor agents fostriecin (CI-920), PD 113,270 and PD 113,271
-
Mamber SW, Okasinski WG, Pinter CD, Tunac JB. Antimycotic effects of the novel antitumor agents fostriecin (CI-920), PD 113,270 and PD 113,271. J Antibiot 1986; 39: 1467-72.
-
(1986)
J Antibiot
, vol.39
, pp. 1467-1472
-
-
Mamber, S.W.1
Okasinski, W.G.2
Pinter, C.D.3
Tunac, J.B.4
-
13
-
-
0021218712
-
Studies on the biochemical mechanism of the novel antitumor agent, CI-920
-
Fry DW, Boritzki TJ, Jackson RC. Studies on the biochemical mechanism of the novel antitumor agent, CI-920. Cancer Chemother Pharmacol 1984; 13: 171-5.
-
(1984)
Cancer Chemother Pharmacol
, vol.13
, pp. 171-175
-
-
Fry, D.W.1
Boritzki, T.J.2
Jackson, R.C.3
-
14
-
-
0025319514
-
Comparison of effects of fostriecin, novobiocin, and camptothecin, inhibitors of DNA topoisomerases, on DNA replication and repair in human cells
-
Gedik CM, Collins AR. Comparison of effects of fostriecin, novobiocin, and camptothecin, inhibitors of DNA topoisomerases, on DNA replication and repair in human cells. Nucleic Acids Res 1990; 18: 1007-13.
-
(1990)
Nucleic Acids Res
, vol.18
, pp. 1007-1013
-
-
Gedik, C.M.1
Collins, A.R.2
-
15
-
-
0023798520
-
Inhibition of type II topoisomerase by fostriecin
-
Boritzki TJ, Wolfard TS, Besserer JA, Jackson RC, Fry DW. Inhibition of type II topoisomerase by fostriecin. Biochem Pharmacol 1988; 37: 4063-8.
-
(1988)
Biochem Pharmacol
, vol.37
, pp. 4063-4068
-
-
Boritzki, T.J.1
Wolfard, T.S.2
Besserer, J.A.3
Jackson, R.C.4
Fry, D.W.5
-
16
-
-
0027140482
-
Teniposide-resistant CEM cells, which express mutant DNA topoisomerase II alpha, when treated with non-complex-stabilizing inhibitors of the enzyme, display no cross-resistance and reveal aberrant functions of the mutant enzyme
-
Chen M, Beck WT. Teniposide-resistant CEM cells, which express mutant DNA topoisomerase II alpha, when treated with non-complex-stabilizing inhibitors of the enzyme, display no cross-resistance and reveal aberrant functions of the mutant enzyme. Cancer Res 1993; 53: 5946-53.
-
(1993)
Cancer Res
, vol.53
, pp. 5946-5953
-
-
Chen, M.1
Beck, W.T.2
-
17
-
-
0029982836
-
Collateral sensitivity to the bisdioxopiperazine dexrazoxan (ICRF-187) in etoposide (VP-16)-resistant human leukemia K562 cells
-
Fattman CL, Allan WP, Hasinoff BB, Yalowich JC. Collateral sensitivity to the bisdioxopiperazine dexrazoxan (ICRF-187) in etoposide (VP-16)-resistant human leukemia K562 cells. Biochem Pharmacol 1996; 52: 635-42.
-
(1996)
Biochem Pharmacol
, vol.52
, pp. 635-642
-
-
Fattman, C.L.1
Allan, W.P.2
Hasinoff, B.B.3
Yalowich, J.C.4
-
18
-
-
0026793818
-
Effect of topoisomerase poisoning by antitumor drugs VM 26, fostriecin and camptothecin on DNA repair replication by mammalian cell extracts
-
Frosina G, Rossi O. Effect of topoisomerase poisoning by antitumor drugs VM 26, fostriecin and camptothecin on DNA repair replication by mammalian cell extracts. Carcinogenesis 1992; 13: 1371-7.
-
(1992)
Carcinogenesis
, vol.13
, pp. 1371-1377
-
-
Frosina, G.1
Rossi, O.2
-
19
-
-
0026076296
-
Lack of cross-resistance to fostriecin in a human small-cell lung carcinoma cell line showing topoisomerase II-related drug resistance
-
de Jong S, Zijlstra JG, Mulder NH, de Vries EGE. Lack of cross-resistance to fostriecin in a human small-cell lung carcinoma cell line showing topoisomerase II-related drug resistance. Cancer Chemother Pharmacol 1991; 28: 461-4.
-
(1991)
Cancer Chemother Pharmacol
, vol.28
, pp. 461-464
-
-
De Jong, S.1
Zijlstra, J.G.2
Mulder, N.H.3
De Vries, E.G.E.4
-
21
-
-
0023792382
-
Combined modalities of resistance in etoposide-resistant human KB cell lines
-
Ferguson PJ, Fisher MH, Stephenson J, Li D, Zhou B, Cheng Y. Combined modalities of resistance in etoposide-resistant human KB cell lines. Cancer Res 1988; 48: 5956-64.
-
(1988)
Cancer Res
, vol.48
, pp. 5956-5964
-
-
Ferguson, P.J.1
Fisher, M.H.2
Stephenson, J.3
Li, D.4
Zhou, B.5
Cheng, Y.6
-
22
-
-
0028063201
-
Antitumor drug fostriecin inhibits the mitotic entry checkpoint and protein phosphatases 1 and 2A
-
Roberge M, Tudan C, Hung SMF, Harder KW, Jirik FR, Anderson H. Antitumor drug fostriecin inhibits the mitotic entry checkpoint and protein phosphatases 1 and 2A. Cancer Res 1994; 54: 6115-21.
-
(1994)
Cancer Res
, vol.54
, pp. 6115-6121
-
-
Roberge, M.1
Tudan, C.2
Hung, S.M.F.3
Harder, K.W.4
Jirik, F.R.5
Anderson, H.6
-
23
-
-
0028828204
-
Cyclins and cyclin dependent kinases: Theme and variations
-
Pines J. Cyclins and cyclin dependent kinases: theme and variations. Adv Cancer Res 1995; 66: 181-212.
-
(1995)
Adv Cancer Res
, vol.66
, pp. 181-212
-
-
Pines, J.1
-
24
-
-
0028931408
-
Chromosome condensation induced by fostriecin does not require p34(cdc2) kinase activity and histone hi hyperphosphorylation, but is associated with enhanced histone h2a and h3 phosphorylation
-
Guo XW, Thng JPH, Swank RA, et al. Chromosome condensation induced by fostriecin does not require p34(cdc2) kinase activity and histone hi hyperphosphorylation, but is associated with enhanced histone h2a and h3 phosphorylation. EMBO J 1995; 14: 976-85.
-
(1995)
EMBO J
, vol.14
, pp. 976-985
-
-
Guo, X.W.1
Thng, J.P.H.2
Swank, R.A.3
-
25
-
-
0029971096
-
The antitumor drug fostriecin induces vimentin hyperphosphorylation and intermediate filament reorganization
-
Ho DT, Roberge M. The antitumor drug fostriecin induces vimentin hyperphosphorylation and intermediate filament reorganization. Carcinogenesis 1996; 17: 967-72.
-
(1996)
Carcinogenesis
, vol.17
, pp. 967-972
-
-
Ho, D.T.1
Roberge, M.2
-
26
-
-
0026593809
-
Cytostatic and cytotoxic effects of fostriecin on human promyelocytic HL-60 and lymphocytic MOLT-4 leukemic cells
-
Hotz MA, Del Bino G, Lassota P, Traganos F, Darzynkiewicz Z. Cytostatic and cytotoxic effects of fostriecin on human promyelocytic HL-60 and lymphocytic MOLT-4 leukemic cells. Cancer Res 1992; 52: 1530-5.
-
(1992)
Cancer Res
, vol.52
, pp. 1530-1535
-
-
Hotz, M.A.1
Del Bino, G.2
Lassota, P.3
Traganos, F.4
Darzynkiewicz, Z.5
-
27
-
-
0026717135
-
Changes in nuclear chromatin related to apoptosis or necrosis induced by the DNA topoisomerase II inhibitor fostriecin in MOLT-4 and HL-60 cells are revealed by altered DNA sensitivity to denaturation
-
Hotz MA, Traganos F, Darzynkiewicz Z. Changes in nuclear chromatin related to apoptosis or necrosis induced by the DNA topoisomerase II inhibitor fostriecin in MOLT-4 and HL-60 cells are revealed by altered DNA sensitivity to denaturation. Exp Cell Res 1992; 201: 184-91.
-
(1992)
Exp Cell Res
, vol.201
, pp. 184-191
-
-
Hotz, M.A.1
Traganos, F.2
Darzynkiewicz, Z.3
-
28
-
-
0027269557
-
Detection of DNA strand breaks in individual apoptotic cells by the in situ terminal deoxynucleotidyl transferase and nick translation assays
-
Gorczyca W, Gong J, Darzynkiewicz Z. Detection of DNA strand breaks in individual apoptotic cells by the in situ terminal deoxynucleotidyl transferase and nick translation assays. Cancer Res 1993; 53: 1945-51.
-
(1993)
Cancer Res
, vol.53
, pp. 1945-1951
-
-
Gorczyca, W.1
Gong, J.2
Darzynkiewicz, Z.3
-
29
-
-
0027205172
-
Induction of DNA strand breaks associated with apoptosis during treatment of leukemias
-
Gorczyca W, Bigman K, Mittelman A, et al. Induction of DNA strand breaks associated with apoptosis during treatment of leukemias. Leukemia 1993; 7: 659-70.
-
(1993)
Leukemia
, vol.7
, pp. 659-670
-
-
Gorczyca, W.1
Bigman, K.2
Mittelman, A.3
-
30
-
-
0027261147
-
The cell cycle related differences in susceptibility of HL-60 cells to apoptosis induced by various antitumor agents
-
Gorczyca W, Gong J, Ardelt B, Traganos F, Darzynkeiwicz Z. The cell cycle related differences in susceptibility of HL-60 cells to apoptosis induced by various antitumor agents. Cancer Res 1993; 53: 3186-92.
-
(1993)
Cancer Res
, vol.53
, pp. 3186-3192
-
-
Gorczyca, W.1
Gong, J.2
Ardelt, B.3
Traganos, F.4
Darzynkeiwicz, Z.5
-
31
-
-
0028986856
-
Distinguishing between folate receptor-alpha-mediated transport and reduced folate carrier-mediated transport in L1210 leukemia cells
-
Spinella MJ, Brigle KE, Sierra EE, Goldman ID. Distinguishing between folate receptor-alpha-mediated transport and reduced folate carrier-mediated transport in L1210 leukemia cells. J Biol Chem 1995; 270: 7842-9.
-
(1995)
J Biol Chem
, vol.270
, pp. 7842-7849
-
-
Spinella, M.J.1
Brigle, K.E.2
Sierra, E.E.3
Goldman, I.D.4
-
32
-
-
0022508842
-
In vitro activity of the novel antitumor antibiotic fostriecin (CI-920) in a human tumor cloning assay
-
Scheithauer W, Von Hoff DD, Clark GM, Shillis JL, Elslager EF. In vitro activity of the novel antitumor antibiotic fostriecin (CI-920) in a human tumor cloning assay. Eur J Cancer Clin Oncol 1986; 22: 921-6.
-
(1986)
Eur J Cancer Clin Oncol
, vol.22
, pp. 921-926
-
-
Scheithauer, W.1
Von Hoff, D.D.2
Clark, G.M.3
Shillis, J.L.4
Elslager, E.F.5
-
33
-
-
0021985089
-
Characterization of a murine leukemia cell line selected for in vivo resistance to fostriecin (phosphotrienin)
-
abstr 1336
-
Howard CT, Leopold WR, Sebolt JS. Characterization of a murine leukemia cell line selected for in vivo resistance to fostriecin (phosphotrienin). Proc Am Ass Cancer Res 1985; 26: 339 (abstr 1336).
-
(1985)
Proc Am Ass Cancer Res
, vol.26
, pp. 339
-
-
Howard, C.T.1
Leopold, W.R.2
Sebolt, J.S.3
-
34
-
-
0024571314
-
Comparison of the effects of flavone acetic acid, fostriecin, homoharringtonine and tumour necrosis factor alpha on colon 38 tumours in mice
-
Baguley BC, Calveley SB, Crowe KK, Fray LM, O'Rourke SA, Smith GP Comparison of the effects of flavone acetic acid, fostriecin, homoharringtonine and tumour necrosis factor alpha on colon 38 tumours in mice. Eur J Cancer Clin Oncol 1989; 25: 263-9.
-
(1989)
Eur J Cancer Clin Oncol
, vol.25
, pp. 263-269
-
-
Baguley, B.C.1
Calveley, S.B.2
Crowe, K.K.3
Fray, L.M.4
O'Rourke, S.A.5
Smith, G.P.6
-
35
-
-
0025327477
-
Response of murine small intestine to combined treatment with fostriecin
-
Rao KR, Fritz-Niggli H. Response of murine small intestine to combined treatment with fostriecin. Br J Radiol 1990; 63: 286-9.
-
(1990)
Br J Radiol
, vol.63
, pp. 286-289
-
-
Rao, K.R.1
Fritz-Niggli, H.2
-
36
-
-
0025007779
-
Preclinical toxicological evaluation of fostriecin, a novel anticancer antibiotic, in rats
-
Susick RL, Jr., Hawkins KL, Pegg DG. Preclinical toxicological evaluation of fostriecin, a novel anticancer antibiotic, in rats. Fundam Appl Toxicol 1990; 15: 258-69.
-
(1990)
Fundam Appl Toxicol
, vol.15
, pp. 258-269
-
-
Susick Jr., R.L.1
Hawkins, K.L.2
Pegg, D.G.3
-
37
-
-
0028353563
-
Determination of fostriecin pharmacokinetics in plasma using high-pressure liquid chromatography assay
-
Pillon L, Moore MJ, Thiessen JJ. Determination of fostriecin pharmacokinetics in plasma using high-pressure liquid chromatography assay. Ther Drug Monit 1994; 16: 186-90.
-
(1994)
Ther Drug Monit
, vol.16
, pp. 186-190
-
-
Pillon, L.1
Moore, M.J.2
Thiessen, J.J.3
-
38
-
-
0025755204
-
Comparative toxicity of fostriecin, hepsulfam and pyrazine diazohydroxide to human and murine hematopoietic progenitor cells in vitro
-
Du DL, Volpe DA, Grieshaber CK, Murphy MJ. Comparative toxicity of fostriecin, hepsulfam and pyrazine diazohydroxide to human and murine hematopoietic progenitor cells in vitro. Invest New Drugs 1991; 9: 149-57.
-
(1991)
Invest New Drugs
, vol.9
, pp. 149-157
-
-
Du, D.L.1
Volpe, D.A.2
Grieshaber, C.K.3
Murphy, M.J.4
-
39
-
-
0028123525
-
Effects of DNA topoisomerase II inhibitors on human bone marrow progenitor cells
-
Francis GE, Tejedor MC, Berney JJ, Chresta CM, Delgado C, Patel P. Effects of DNA topoisomerase II inhibitors on human bone marrow progenitor cells. Leukemia 1994; 8: 121-8.
-
(1994)
Leukemia
, vol.8
, pp. 121-128
-
-
Francis, G.E.1
Tejedor, M.C.2
Berney, J.J.3
Chresta, C.M.4
Delgado, C.5
Patel, P.6
-
40
-
-
7144227420
-
Phase I clinical and pharmacokinetic study of 5 days 1 hour infusion of fostriecin in patients with solid tumors
-
abstr 351
-
De Jong RS, Mulder NH, Uges DRA, van der Graaf WTA, Meijer S, de Vries EGE. Phase I clinical and pharmacokinetic study of 5 days 1 hour infusion of fostriecin in patients with solid tumors. Ann Oncol 1996; 7(suppl 1): 100 (abstr 351).
-
(1996)
Ann Oncol
, vol.7
, Issue.1 SUPPL.
, pp. 100
-
-
De Jong, R.S.1
Mulder, N.H.2
Uges, D.R.A.3
Van Der Graaf, W.T.A.4
Meijer, S.5
De Vries, E.G.E.6
-
41
-
-
0026652116
-
The biological chemistry of folate receptors
-
Antony A. The biological chemistry of folate receptors. Blood 1992; 79: 2807-20.
-
(1992)
Blood
, vol.79
, pp. 2807-2820
-
-
Antony, A.1
-
42
-
-
0029945736
-
Intestinal folate transport: Identification of a cDNA involved in folate transport and the functional expression and distribution of its mRNA
-
Said HM, Nguyen TT, Dyer DL, Cowan KH, Rubin SA. Intestinal folate transport: identification of a cDNA involved in folate transport and the functional expression and distribution of its mRNA. Biochim Biophys Acta 1996; 1281: 164-72.
-
(1996)
Biochim Biophys Acta
, vol.1281
, pp. 164-172
-
-
Said, H.M.1
Nguyen, T.T.2
Dyer, D.L.3
Cowan, K.H.4
Rubin, S.A.5
-
43
-
-
85036483394
-
Phase I clinical and pharmacologic study of fostriecin in patients with advanced cancer
-
abstr 321
-
Schilsky RL, Ramirez J, Wilson K, et al. Phase I clinical and pharmacologic study of fostriecin in patients with advanced cancer. Proc Am Soc Clin Oncol 1994; 13: 132 (abstr 321).
-
(1994)
Proc Am Soc Clin Oncol
, vol.13
, pp. 132
-
-
Schilsky, R.L.1
Ramirez, J.2
Wilson, K.3
-
44
-
-
85036491923
-
Phase I clinical and pharmacokinetic evaluation of fostriecin (CI-920)
-
abstr 455
-
Thenault R, Schmidt S, Newman RA, Raber M, Hortobagyi G. Phase I clinical and pharmacokinetic evaluation of fostriecin (CI-920). Proc Am Soc Clin Oncol 1994; 13: 165 (abstr 455).
-
(1994)
Proc Am Soc Clin Oncol
, vol.13
, pp. 165
-
-
Thenault, R.1
Schmidt, S.2
Newman, R.A.3
Raber, M.4
Hortobagyi, G.5
-
45
-
-
85036489621
-
A phase I clinical and pharmacokinetic study of fostriecin in a daily X 5 schedule
-
abstr 1537
-
Moore MJ, Erlichman C, Pillon L, Manzo J, Thiessen JJ, Eisenhauer E. A phase I clinical and pharmacokinetic study of fostriecin in a daily X 5 schedule. Proc Am Soc Clin Oncol 1995; 14: 474 (abstr 1537).
-
(1995)
Proc Am Soc Clin Oncol
, vol.14
, pp. 474
-
-
Moore, M.J.1
Erlichman, C.2
Pillon, L.3
Manzo, J.4
Thiessen, J.J.5
Eisenhauer, E.6
|