Norketamine, the main metabolite of ketamine, is a non-competitive NMDA receptor antagonist in the rat cortex and spinal cord

European Journal of Pharmacology

Volumn 333, Issue 1, 1997, Pages 99-104

  Ebert, Bjarke ^a   Mikkelsen, Søren ^b   Thorkildsen, Christian ^a   Borgbjerg, Finn Molke ^b  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b BISPEBJERG HOSPITAL   (Denmark)

Author keywords

Cortex, rat; Electrophysiology; Enantiomer; NMDA receptor antagonist; Non competitive; Spinal cord, rat

Indexed keywords

DIZOCILPINE; DRUG METABOLITE; KETAMINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NORKETAMINE; PHENCYCLIDINE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; DRUG RECEPTOR BINDING; ENANTIOMER; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL CORD;

ANIMALS; ANIMALS, NEWBORN; BINDING, COMPETITIVE; CEREBRAL CORTEX; DIZOCILPINE MALEATE; ELECTROPHYSIOLOGY; EXCITATORY AMINO ACID ANTAGONISTS; KETAMINE; PHENCYCLIDINE; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; RECEPTORS, N-METHYL-D-ASPARTATE; SPINAL CORD; STEREOISOMERISM;

EID: 0030820271     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(97)01116-3     Document Type: Article

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