The cornerstones and directions of pediatric burn care

Pediatric Surgery International

Volumn 12, Issue 5-6, 1997, Pages 312-320

  Wolf, S E ^a,b   Debroy, M ^a   Herndon, D N ^a  

^a UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

^b NONE   (United States)

Author keywords

Burns; Inhalation injury; Metabolism; Resuscitation; Wound healing

Indexed keywords

ACETYLCYSTEINE; ANTIHISTAMINIC AGENT; GROWTH HORMONE; HEPARIN; HISTAMINE H2 RECEPTOR ANTAGONIST; INSULIN; METOPROLOL; PROPRANOLOL;

ARTIFICIAL VENTILATION; BURN; BURN EXCISION; CHILD; CONFERENCE PAPER; EDEMA; GAS EXCHANGE; HUMAN; HYPERMETABOLISM; INHALATIONAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; LUNG BURN; MEDICAL RESEARCH; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RESUSCITATION; SKIN GRAFT; TACHYCARDIA; TREATMENT OUTCOME; WOUND HEALING;

EID: 0030819923     PISSN: 01790358     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF01076929     Document Type: Conference Paper

References (63)

1. Bull JP, Fisher AJ (1949) A study of mortality in a burns unit: standards for the evaluation of alternative methods of treatments. Ann Surg 130: 160-173
2. Herndon DN, Gore DC, Cole M, Desai MH, Linares H, Abston S, Rutan TC, Van Osten T, Barrow RE (1987) Determinants of mortality in pediatric patients with greater than 70% full-thickness total body surface area thermal injury treated by early total excision and grafting. J Trauma 27: 208-212
3. Wolf SE, Rose JK, Desai MH, Mileski JH, Barrow RE, Herndon DN (in press) Mortality determinants in massive pediatric burns: an analysis of 103 children with greater than 80% TBSA burns (70% full-thickness). Ann Surg
4. Warden GD (1996) Fluid resuscitation and early management. In: Herndon DN, Total burn care. Saunders, Philadelphia, pp 53-60
5. Leape L (1970) Initial changes in burns, tissue changes in burned and unburned skins in Rhesus monkeys. J Trauma 10: 488-492
6. Carvajal HF, Brouhard BH, Linares HA (1975) Effect of antihistamine, anti-serotonin, and ganglionic blocking agents upon increased capillary permeability following burn trauma. J Trauma 15: 969-975
7. Boykin JV, Crute SL, Haynes BW (1985) Cimetidine therapy for burn shock: a quantitative assessment. J Trauma 25: 864-870
8. Holliman CJ, Meuleman TR, Larsen KR, Port JD, Stanley TH, Pace NL, Warden GD (1983) The effect of ketanserin, a specific serotonin antagonist, on burn shock hemodynamic parameters in a porcine burn model. J Trauma 23: 867-871
9. 2 levels in the plasma of burned and septic burned patients. Surg Gynecol Obstet 159: 210-213
10. Heggers JP, Loy GL, Robson MC, Delbaccaro EJ (1980) Histological demonstration of prostaglandins and thromboxanes in burned tissues. J Surg Res 28: 110-117
11. Baxter CR (1974) Fluid volume and electrolyte changes in the early post-burn period. Clin Plast Surg 1: 693-703
12. Pruitt BA, Mason AD, Moncrief JA (1971) Hemodynamic changes in the early post burn patient: the influence of fluid administration and of a vasodilator (hydralazine). J Trauma 11: 36-46
13. Demling RH, Mazess RB, Witt RM, Wolbert WH (1978) The study of burn wound edema using dichosmatic absorptionmetry. J Trauma 18: 124-128
14. Demling RH, Gunther RA, Haines B, Kramer G (1982) Burn edema. Part II: Complications, prevention, and treatment. J Burn Care Rehabil 3: 199-206
15. Monafo WW (1970) The treatment of burn shock by the intravenous and oral administration of hypertonic lactated saline solution. J Trauma 10: 575-586
16. Gunn ML, Hansbrough JF, Davis JW, Furst SR, Field TO (1989) Prospective randomized trial of hypertonic sodium lactate vs. lactated Ringer's solution for burn shock resuscitation. J Trauma 29: 1261-1267
17. Huang PP, Stucky FS, Dimick AR, Treat RC, Bessey PQ, Rue LW (1995.) Hypertonic sodium resuscitation is associated with renal failure and death. Ann Surg 221: 543-554
18. Du G, Slater H, Goldfarb IW (1991) Influence of different resuscitation regimens on acute weight gain in extensively burned patients. Burns 17: 147-150
19. Graves TA, Cioffi WG, McManus WF, Mason AD, Pruitt BA (1988) Fluid resuscitation of infants and children with massive thermal injury. J Trauma 28: 1656-1659
20. Wilmore DW, Long JM, Mason AD, et al. (1974) Catecholamines: mediator of the hypermetabolic response to thermal injury. Ann Surg 180: 653-668
21. Aulick H, Wilmore DW (1979) Increased peripheral amino acid release following thermal injury. Surgery 85: 560-565
22. Clowes GHA, Randell HT, Cha CJ (1980) Amino acid and energy metabolism in septic and traumatized patients. J Parent Ent Nutr 4: 195-203
23. Wildmueller HG, Spaeth AE (1975) Intestinal metabolism of glutamine and glutamate from the lumen compared to glutamine from the blood. Arch Biochem Biophys 171: 662-677
24. Wolfe RR (1996) Metabolic responses to burn injury: nutritional implications. In: Herndon DN (ed) Total burn care. Saunders, Philadelphia, pp 217-222
25. Wolf SE, Barrow RE, Herndon DN (1996) Growth hormone and IGF-1 therapy in the hypercatabolic patient. Baillieres Clin Endocrinol Metab 10: 447-463
26. Wolfe RR, Klein S, Herndon DN, Jahoor F (1990) Substrate cycling in thermogenesis and amplification of net substrate flux in human volunteers and burned patients. J Trauma 30: S6-S9
27. Curreri PW, Richmond D, Marvin J, Baxter CR (1974) Dietary requirements of patients with major burns. J Am Diet Assoc 65: 415-417
28. Hildreth MA, Herndon DN, Desai MH, Duke MA (1989) Caloric needs of adolescent patients with burns. J Burn Care Rehabil 100: 523-526
29. Wolfe RR (1981) Caloric requirements of the burned patient. J Trauma 21: 712-714
30. Goran MI, Broemeling L, Herndon DN, Peters EJ, Wolfe RR (1991) Estimating energy requirements in burned children: a new approach derived from measurements of resting energy expenditure. Am J Clin Nutr 54: 35-40
31. Herndon DN, Barrow RE, Stein M, Linares H, Rutan TC, Rutan R, Abston S (1989) Increased mortality with intravenous supplemental feeding in severely burned patients. J Burn Care Rehabil 10: 309-313
32. Gore DC, Honeycutt D, Jahoor F, Wolfe RR, Herndon DN (1991) Effect of exogenous growth hormone on whole-body and isolated limb kinetics in burned patients. Arch Surg 126: 38-43
33. Herndon DN, Barrow RE, Kunkel KR, Broemeling LD, Rutan RL (1990) Effects of recombinant human growth hormone on donor-site healing in severely burned children. Ann Surg 212: 424-431
34. Gilpin DA, Barrow RE, Rutan RL, Broemeling LD, Herndon DN (1994) Recombinant human growth hormone accelerates wound healing in children with large cutaneous burns. Ann Surg 220: 19-24
35. Fleming RYD, Rutan RL, Jahoor F, Barrow RE, Wolfe RR, Herndon DN (1992) Effects of recombinant growth hormone on catabolic hormones and free fatty acids following thermal injury. J Trauma 32: 698-702
36. Herndon DN, Hawkins HK, Nguyen TT, Pierre E, Cox R, Barrow RE (1995) Characterization of growth hormone enhanced donor site healing in patients with large cutaneous burns. Ann Surg 221: 649-659
37. Cioffi WG, Gore DC, Rue LC, Carrougher G, Guler HP, McManus WF, Pruitt BA (1994) Insulin-like growth factor-I lowers protein oxidation in patients with thermal injury. Ann Surg 220: 310-319
38. Lieberman SA, Butterfield GE, Harrison D, Hoffman AR (1994) Anabolic effects of recombinant insulin-like growth factor-1 in cachectic patients with the acquired immunodeficiency syndrome. J Clin Endocrinol Metab 78: 404-410
39. Sakuri Y, Aarsland AA, Herndon DN, Chinkes DL, Pierre EJ, Nguyen TT, Patterson BW, Wolfe RR (1995) Stimulation of muscle protein synthesis by long-term insulin infusion in severely burned patients. Ann Surg 222: 283-297
40. Pierre EJ, Barrow RE, Sakuri Y, Wolfe RR, Herndon DN (1995) Structural effects of insulin on wound healing. Surg Forum 46: 743-745
41. Herndon DN, Barrow RE, Rutan TC, Minifee P, Jahoor F, Wolfe RR (1988) Effect of propanolol administration on hemodynamic and metabolic responses of burned pediatric patients. Ann Surg 208: 484-492
42. 2 receptor for catecholamines. Arch Surg 129: 1301-1305
43. Aarsland AA, Chinkes D, Wolfe RR, Barrow RE, Nelson SO, Pierre EJ, Herndon DN (1996) Beta-blockade lowers peripheral lipolysis in burn patients receiving growth hormone. Ann Surg 222: 777-789
44. Herndon DN, Parks DH (1986) Comparison of serial debridement and autografting and early massive excision with cadaver skin overlay in the treatment of large burns in children. J Trauma 26: 149-152
45. Thompson P, Herndon DN, Abston S, Rutan TC (1987) Effect of early excision on patients with major thermal injury. J Trauma 27: 205-207
46. Desai MH, Rutan RL, Herndon DN (1991) Conservative treatment of scald burns is superior to early excision. J Burn Care Rehabil 12: 482-484
47. Atiles L, Mileski W, Purdue G, Hunt J, Baxter C (1995) Laser doppler flowmetry in burn wounds. J Burn Care Rehabil 16: 388-393
48. Heimbach DM, Afromowitz MA, Engrav LH, Marvin JA, Perry B (1984) Burn depth estimation - man or machine. J Trauma 24: 373-378
49. Thompson PB, Herndon DN, Traber DL, Abston S (1986) Effect on mortality of inhalation injury. J Trauma 26: 163-165
50. Smith DL, Cairns BA, Ramadan F, Dalston JS, Fakhry SM, Rutledge R, Meyer AA, Peterson HD (1994) Effect of inhalation injury, burn size, and age on mortality: a study of 1447 consecutive burn patients. J Trauma 37: 655-659
51. Rue LW, Cioffi WG, Mason AD, McManus WF, Pruitt BA (1993) Improved survival of burned patients with inhalation injury. Arch Surg 128: 772-780
52. Herndon DN, Traber DL, Niehaus GD, Linares HA, Traber LD (1984) The pathophysiology of smoke inhalation in a sheep model. J Trauma 24: 1044-1051
53. Barrow RE, Morris SE, Basadre JO, Herndon DN (1990) Selective permeability changes in the lungs and airways of sheep after toxic smoke inhalation. J Appl Physiol 68: 2165-2170
54. Ashley KD, Stothert JC, Traber DL, Traber LD, Kramer G, Herndon DN (1990) Airway blood flow following light and heavy smoke inhalation injury. Surg Forum 41: 293-295
55. Loick HM, Traber LD, Tokyay R, Linares HA, Prien T, Traber DL (1992) Mechanical alteration of blood flow in smoked and unsmoked areas after inhalation injury. J Appl Physiol 72: 1692-1700
56. Basadre JO, Sugi K, Traber DL, Traber LD, Niehaus GD, Herndon DN (1988) The effect of leukocyte depletion on smoke inhalation injury in sheep. Surgery 104: 208-215
57. Hubbard GB, Langlinais PC, Shimazu T, Okerberg CV, Mason AD, Pruitt BA (1991) The morphology of smoke inhalation injury in sheep. J Trauma 31: 1477-1486
58. Fitzpatrick JC, Cioffi WG (1996) Diagnosis and treatment of inhalation injury. In: Herndon DN (ed) Total burn care. Saunders, Philadelphia, pp 184-192
59. Cox CS, Zwishenberger JB, Traber DL, Traber LD, Haque AK, Herndon DN (1993) Heparin improves oxygenation and minimizes barotrauma after severe smoke inhalation in an ovine model. Surg Gynecol Obstet 176: 339-349
60. Brown M, Desai MH, Traber LD, Herndon DN, Traber DL (1988) Dimethylsulfoxide with heparin in the treatment of smoke inhalation injury. J Burn Care Rehabil 9: 22-25
61. Desai MH, Mlcak R, Richardson J, Nichols RJ, Herndon DN (1996) Reduction in mortality in pediatric burn patients with inhalation injury with aerosolized heparin/acetylcysteine therapy. Proc Am Burn Assoc 28: 48
62. Levine BA, Petroff PA, Slade CL (1978) Prospective trials of dexamethasone and aerosolized gentamycin in the treatment of inhalation injury in the burned patient. J Trauma 18: 188-193
63. Cioffi WG, Graves TA, McManus WF, Pruitt BA (1989) High-frequency percussive ventilation in patients with inhalation injury. J Trauma 29: 1350-1354