Structure-activity relationship of a series of C-terminus modified aminoalkyl, diaminoalkyl- and anilino-containing analogues of the benzoic acid mustard distamycin derivative tallimustine: Synthesis, DNA binding and cytotoxicity studies

Bioorganic and Medicinal Chemistry

Volumn 5, Issue 8, 1997, Pages 1497-1507

  Brooks, Natalie ^a   Hartley, John A ^a   Simpson Jr , Jacob E ^b   Wright, Stephen R ^b   Woo, Shirley ^b   Centioni, Sara ^b   Fontaine, Michael D ^b   McIntyre, Terry E ^b   Moses, Lee ^b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b FURMAN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CHLORMETHINE DERIVATIVE; DISTAMYCIN A DERIVATIVE; TALLIMUSTINE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CELL STRAIN K 562; CHRONIC MYELOID LEUKEMIA; CYTOTOXICITY; DNA BINDING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; STRUCTURE ACTIVITY RELATION;

EID: 0030819908     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(97)00096-5     Document Type: Article

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