T cell response of I-A(q) mice to self type II collagen: Meshing of the binding motif of the I-A(q) molecule with repetitive sequences results in autoreactivity to multiple epitopes

International Immunology

Volumn 9, Issue 11, 1997, Pages 1687-1699

  Bayrak, Şinasi ^a,b   Holmdahl, Rikard ^b   Travers, Paul ^c   Lauster, Roland ^a   Hesse, Matthias ^a   Dölling, Rudolf ^d   Mitchison, N Avrion ^a  

^a DEUTSCHES RHEUMA FORSCHUNGSZENTRUM   (Germany)

^b LUND UNIVERSITY   (Sweden)

^c UNIVERSITY OF LONDON   (United Kingdom)

^d BioTeZ Berlin Buch GmbH   (Germany)

Author keywords

Class II binding motif; Epitope analysis; I A(q) binding motif; Meshing; Mouse type II collagen; Repetitive sequences; T cell autoreactivity

Indexed keywords

COLLAGEN TYPE 2; EPITOPE;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN BINDING; ANTIGEN RECOGNITION; ARTICLE; CELLULAR IMMUNITY; COMPUTER MODEL; CONTROLLED STUDY; MAJOR HISTOCOMPATIBILITY COMPLEX RESTRICTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE;

AMINO ACID SEQUENCE; ANIMALS; ARTHRITIS, EXPERIMENTAL; BINDING SITES; CLONING, MOLECULAR; COLLAGEN; DNA, COMPLEMENTARY; EPITOPES; HISTOCOMPATIBILITY ANTIGENS CLASS II; LYMPH NODES; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED DBA; MOLECULAR SEQUENCE DATA; RATS; REPETITIVE SEQUENCES, NUCLEIC ACID; T-LYMPHOCYTES;

EID: 0030819263     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/9.11.1687     Document Type: Article

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