Different apparent modes of inhibition of α(2A)-adrenoceptor by α2-adrenoceptor antagonists

European Journal of Pharmacology

Volumn 335, Issue 1, 1997, Pages 99-105

  Kukkonen, Jyrki P ^a,b,c   Huifang, Ge ^b   Jansson, Christian C ^c   Wurster, Siegfried ^d   Cockcroft, Vic ^d   Savola, Juha Matti ^d   Åkerman, Karl E O ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b ÅBO AKADEMI UNIVERSITY   (Finland)

^c UNIVERSITY OF TURKU   (Finland)

^d ORION CORPORATION   (Finland)

Author keywords

2 Adrenoceptor; Ca2+ signaling; Fura 2; Receptor binding; Receptor kinetics

Indexed keywords

1,3,4,5',6,6',7,12B OCTAHYDRO 1',3' DIMETHYL 2H SPIRO[BENZO[B]FURO[2,3 A]QUINOLIZINE 2,4' PYRIMIDINE] 2' ONE; 2 (2 METHOXY 1,4 BENZODIOXAN 2 YL) 2 IMIDAZOLINE; ALPHA 2 ADRENERGIC RECEPTOR; ALPHA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; ATIPAMEZOLE; DETOMIDINE; GUANFACINE; IDAZOXAN; MEDETOMIDINE; OXYMETAZOLINE; RAUWOLSCINE; YOHIMBINE;

ARTICLE; CONTROLLED STUDY; DISSOCIATION; DOSE RESPONSE; DRUG RECEPTOR BINDING; ERYTHROLEUKEMIA CELL; HUMAN; HUMAN CELL; KINETICS; MODEL; PRIORITY JOURNAL;

ADRENERGIC ALPHA-ANTAGONISTS; HUMANS; IDAZOXAN; QUINOLIZINES; RECEPTORS, ADRENERGIC, ALPHA-2; TRITIUM; TUMOR CELLS, CULTURED; YOHIMBINE;

EID: 0030819156     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(97)01180-1     Document Type: Article

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