Disturbances of neuromuscular interaction may contribute to muscle weakness in spinal muscular atrophy

Neuromuscular Disorders

Volumn 7, Issue 6-7, 1997, Pages 369-372

  Greensmith, Linda ^a   Vrbová, Gerta ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Development; Motoneurone survival; Muscle fibres; Transmitter release

Indexed keywords

DEVELOPMENT; GENE DELETION; GENE ISOLATION; HUMAN; MOTONEURON; MUSCLE; MUSCLE FUNCTION; MUSCLE WEAKNESS; NEUROMUSCULAR DISEASE; NEUROMUSCULAR FUNCTION; PERINATAL PERIOD; PRIORITY JOURNAL; SHORT SURVEY; SPINAL MUSCULAR ATROPHY; SURVIVAL; SYMPTOM;

EID: 0030818309     PISSN: 09608966     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-8966(97)00047-3     Document Type: Article

References (26)

1. Dubowitz, V. Muscle disorders in childhood. London: WB Saunders, 1978.
2. Hausmanowa-Petrusewicz I. A research strategy for the resolution of childhood spinal muscular atrophy (SMA). In: Merlini L, Granata C, Dubowitz V, editors. Current concepts in childhood spinal muscular atrophy. Vienna: Springer-Verlag and Bologna: Aulo Gaggi Editore, 1989;21-32.
3. Vrbová G, Lowrie MB. The role of nerve-muscle interactions in the pathogenesis of spinal muscular atrophy. In: Merlini L, Granata C, Dubowitz V, editors. Current concepts in childhood spinal muscular atrophy. Vienna: Springer Verlag and Bologna: Aulo Gaggi Editore, 1989;33-42.
4. Braun S, Croizat B, Lagrange MC, Warter JM, Poindron P. Constitutive muscular abnormalities in culture in spinal muscular atrophy. Lancet 1995;345:694-695.
5. Morrison KE. Advances in SMA research: review of gene deletions. Neuromusc Disord 1996;6:397-408.
6. Melki J, Lefebvre S, Burglen L, et al. De novo and inherited deletion of the Sq13 region in spinal muscular atrophies. Science 1994;264:1474-1476.
7. Roy N, Mahadevan MS, McLean M, et al. The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy. Cell 1995;80:167-178.
8. Lowrie MB, Vrbová G. Different pattern of recovery of fast and slow muscles following nerve iniury in the rat. J Physiol 1984;349:397-410.
9. Greensmith L, Hind AH, Vrbová G. Transient disruption of nerve-muscle interaction shortly after birth permanently alters the development of the rat soleus muscle. Dev Brain Res 1996;94:152-158.
10. Lowrie MB, Vrbová G. Different pattern of recovery of fast and slow muscles following nerve injury in the rat. J Physiol 1984;349:397-410.
11. Naidu MDK, Subramaniam K, Vrbová G. Re-innervation of muscles after nerve injury in neonates. Restor Neurol Neurosci 1996;10:35-42.
12. Sieradzan K, Vrbová G. The ability of developing spinal neurons to reinnervate a muscle through a peripheral nerve conduit is enhanced by cografted embryonic spinal cord. Exp Neurol 1993;122:232-243.
13. Greensmith L, Vrbová G. Neuromuscular contacts in the developing rat soleus depend on muscle activity. Dev Brain Res 1991;62:121-129.
14. Greensmith L, Vrbová G. Alterations of nerve-muscle interactions during postnatal development influence motoneurone survival in rats. Dev Brain Res 1992;69:125-131.
15. Hamburger V. Motor and sensory hyperplasia following limb bud transplants in chick embryos. Physiol Zool 1939;12:268-284.
16. Burt AM. Choline acetyltransferase and acetylcholinesterase in the developing rat spinal cord. Exp Neurol 1975;47:173-180.
17. Phelps PE, Barber RP, Houser CR, Crawford GD, Salvaterra PM, Vaughn JE. Postnatal development of neurons containing choline acetyltransferase in rat spinal cord: an immunocytochemical study. J Comp Neurol 1984;229:347-361.
18. Caroni P, Becker M. The downregulation of growth-associated proteins in motoneurons at the onset of synapse elimination is controlled by muscle activity and IGF 1. J Neurosci 1992;12:3849-3861.
19. Duxson MJ. The effect of postsynaptic block on development of the neuromuscular junction in postnatal rats. J Neurocytol 1982;11:395-408.
20. Greensmith L, Vrbová G. Neuromuscular contacts in the developing rat soleus depend upon muscle activity. Dev Brain Res 1991;62:121-129.
21. Xie Z, Poo M-M. Initial events in the formation of neuromuscular synapse: rapid induction of acetylcholine release from embryonic neuron. Proc Natl Acad Sci USA 1986;83:7069-7073.
22. Lohof AM, Ip NY, Poo M-M. Potentiation of developing neuromuscular synapses by the neurotrophins NT-3 and BDNF. Nature 1993;363:350-353.
23. Greensmith L, Hasan HI, Vrbová G. Nerve injury increases the susceptibility of motoneurones to NMDA-induced neurotoxicity in the developing rat. Neuroscience 1994;58:727-733.
24. Mentis GZ, Greensmith L, Vrbová G. Motoneurones destined to die are rescued by blocking NMDA receptors by MK-801. Neuroscience 1993;54:283-285.
25. Greensmith L, Mentis GZ, Vrbová G. Blockade of NMDA receptors by MK-801 rescues motoneurones in developing rats. Dev Brain Res 1994;81:162-170.
26. Greensmith L, Dick J, Emanuel AO, Vrbová G. Induction of transmitter release at the neuromuscular junction prevents motoneurone death after axotomy in neonatal rats. Neuroscience 1996;71:213-220.