Antibodies to desmin identify the blastemal component of nephroblastoma

Modern Pathology

Volumn 10, Issue 9, 1997, Pages 895-900

  Folpe, Andrew L ^a,b   Patterson, Kathleen ^a   Gown, Allen M ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF WASHINGTON MEDICAL CENTER   (United States)

Author keywords

Desmin; Immunohistochemistry; Myogenic nuclear regulatory proteins; Nephroblastoma; Rhabdomyosarcoma

Indexed keywords

ACTIN; ANTIBODY; DESMIN; EPITOPE; MYOGENIN; PROTEIN;

ARTICLE; BLASTEMA; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; NEPHROBLASTOMA; PRIORITY JOURNAL; RHABDOMYOSARCOMA;

ACTINS; DESMIN; DIAGNOSIS, DIFFERENTIAL; HUMANS; IMMUNOHISTOCHEMISTRY; KIDNEY NEOPLASMS; MYOD PROTEIN; MYOGENIN; RHABDOMYOSARCOMA; WILMS TUMOR;

EID: 0030818089     PISSN: 08933952     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. Sternberg SS, editor. Diagnostic surgical pathology. Vol. 1. 2nd ed. New York: Raven Press; 1994. p. 1745.
2. Breslow NG, Beckwith JB, Ciol M, Sharples K. Age distribution of Wilms' tumor. Report from the National Wilms' Tumor Study. Cancer Res 1988;48:1653-7.
3. Roald B, Brandtzaeg P. Immunohistochemistry on needle biopsies of childhood malignancies. Pathol Res Pract 1991; 187:917-23.
4. Pilkington GR, Pallesen G. Phenotypic characterization of non-hematopoietic small cell tumors of childhood with monoclonal antibodies to leukocytes, epithelial cells, and cytoskeletal proteins. Histopathology 1989;14:347-57.
5. Albeda FW, Molenaar WM, de Leij L, Thijs-Ipema AH. Heterogeneity of Wilms' tumor blastema: an immunohistochemical study. Virchows Archiv A Pathol Anat Histopathol 1989;414:263-71.
6. Simpson RM, Gliatto JM, Casey HW, Henk WG. The histologic, ultrastructural, and immunohistochemical features of a blastema-predominant canine nephroblastoma. Vet Pathol 1992;29:250-3.
7. Roth J, Zuber C, Wagner P, Taatjes DJ, Weisgerber C, Heitz PU, et al. Re-expression of poly(sialic acid) units of the neural cell adhesion molecule in Wilms' tumor. Proc Natl Acad Sci U S A 1988;85:2999-3003.
8. Ogawa K, Nakashima Y, Yamabe H, Hamashima Y. Clear cell sarcoma of the kidney: an immunohistochemical study. Acta Pathol Jpn 1986;36:681-9.
9. Denk H, Weybora W, Ratshek M, Sohar R, Franke WW. Distribution of vimentin, cytokeratins, and desmosomalplaque proteins in human nephroblastoma as revealed by specific antibodies: co-existence of cell groups of different degrees of epithelial differentiation. Differentiation 1985;29: 88-97.
10. Sapi Z, Svastics E. Adult Wilms' tumor. A case report with immunohistochemical studies. Acta Morphol Hung 1990;38: 55-60.
11. Magee F, Mah RG, Taylor GP, Dimmick JE. Neural differentiation in Wilms' tumor. Hum Pathol 1987;18:33-7.
12. Carter RL, Al-Sams SZ, Corbett RP, Clinton S. A comparative study of immunohistochemical staining for neuron-specific enolase, protein gene product 9.5. and S-100 protein in neuroblastoma, Ewing's sarcoma, and other round cell tumors in children. Histopathology 1990;16:461-7.
13. Tarnowski BI, Hazen-Martin DJ, Garvin J, Sens MA, Sens DA. Characterization of a monoclonal antibody recognizing the blastemal element of Wilms' tumors and fetal kidneys. Pediatr Pathol 1994;14:849-62.
14. Parham DM, Dias P, Kelly DR, Rutledge JC, Houghton P. Desmin positivity in primitive neuroectodermal tumors of childhood. Am J Surg Pathol 1992;16:483-92.
15. Wang NP, Marx J, McNutt MA, Rutledge JC, Gown AM. Expression of myogenic regulatory proteins (myogenin and MyoD1) in small blue round cell tumors of childhood. Am J Pathol 1995;147:1799-810.
16. Venuti JM, Horris JH, Vivian JL, Olson EN, Klein WH. Myogenin is required for late but not early aspects of myogenesis during mouse development. J Cell Biol 1995;128:563-76.
17. Weintraub H. The MyoD family and myogenesis: redundancy, networks, and thresholds. Cell 1993;75:1241-4.
18. Dias P, Parham DM, Shapiro DN, Tapscott SJ, Houghton PJ. Monoclonal antibodies to the myogenic regulatory protein MyoD1: epitope mapping and diagnostic utility. Cancer Res 1992;52:6431-9.
19. Wright WE, Binder M, Funk W. Cyclic amplification and selection of targets (CASTing) for the myogenin consensus binding site. Mol Cell Biol 1991;11:4104-10.
20. Tsokos M, Dias P, Jefferson J, Houghton PJ. Detection of the MyoD1 gene product in paraffin sections of pediatric tumors [abstract]. Mod Pathol 1994;7:148A.
21. Dias P, Parham DM, Shapiro DN, Webber BL, Houghton PJ. Myogenic regulatory protein (MyoD1) expression in childhood solid tumors: diagnostic utility in rhabdomyosarcoma. Am J Pathol 1990;137:1283-91.
22. Wesche WA, Fletcher CDM, Dias P, Houghton PJ, Parham DM. Immunohistochemistry of MyoD1 in adult pleomorphic soft tissue sarcomas. Am J Surg Pathol 1995;19:261-9.
23. Gown AM, de Wever N, Battifora H. Microwave-based antigenic unmasking: a revolutionary new technique for routine immunohistochemistry. Appl Immunohistochem 1993;1:256-66.
24. True, LD. Atlas of diagnostic immunohistopathology. New York, NY: Gower; 1990. p. 4.7-4.8.
25. Altmannsberger M, Weber K, Droste R, Osborn M. Desmin is a specific marker of rhabdomyosarcomas of human and rat origin. Am J Pathol 1985;118:85-95.
26. Tsokos M. The role of immunocytochemistry in the diagnosis of rhabdomyosarcoma. Arch Pathol Lab Med 1986;110: 776-8.
27. Truong LD, Randaeng S, Cagle P, Ro JY, Hawkins H, Font RL. The diagnostic utility of desmin. Am J Clin Pathol 1990;93: 305-14.
28. Miettinin M, Lehto VP, Bradley RA, Virtanen I. Alveolar rhabdomyosarcoma: demonstration of the muscle type of intermediate filament, desmin, as a diagnostic aid. Am J Pathol 1982;108:246-51.
29. Hurlimann J. Desmin and neural marker expression in mesothelial cells and mesothelioma. Hum Pathol 1994;25:753-7.
30. Zeng L, Fleury-Feith J, Monnet I, Boutin C, Bignon J, Jaurand MC. Immunocytochemical characterization of cell lines from human malignant mesothelioma: characterization of human mesothelioma cell lines by immunocytochemistry with a panel of monoclonal antibodies. Hum Pathol 1994; 25:227-34.
31. Rangdaeng S, Truong LD. Comparative immunohistochemical staining for desmin and muscle-specific actin: a study of 576 cases. Am J Clin Pathol 1991;96:32-45.
32. Wang NP, Bacchi CE, Jiang JJ, McNutt MA, Gown MA. Does alveolar soft part sarcoma exhibit skeletal muscle differentiation? An immunocytochemical and biochemical study of myogenic regulatory protein expression. Mod Pathol 1996;9: 496-501.
33. Parham DM, Webber B, Holt H, Williams WK, Maurer H. Immunohistochemical study of childhood rhabdomyosarcomas and related neoplasms: results of an intergroup rhabdomyosarcoma study project. Cancer 1991;67:3072-80.
34. Sugimoto T, Ueyama H, Hosoi H, Inazawa J, Kato T, Reynolds CP, et al. α smooth-muscle actin and desmin-positive human neuroblastoma cell lines. Int J. Cancer 1991;48:277-83.
35. Garrels JI, Gibson W. Identification and characterization of multiple forms of actin. Cell 1976;9:793-805.
36. Tsukada T, McNutt MA, Ross R, Gown AM. HHF-35, a muscle-actin-specific monoclonal antibody. II. Reactivity in normal, reactive, and neoplastic human tissues. Am J Pathol 1987;127:389-402.
37. Schmidt, RA, Cone R, Haas JE, Gown AM. Diagnosis of rhabdomyosarcoma with HHF35, a monoclonal antibody directed against muscle actins. Am J Pathol 1988;131:19-28.
38. van Leeuwen EH, Postma A, Oosterhuis JW, Meiring A, Cornelisse CJ, Koudstaal J, et al. An analysis of histology and DNA-ploidy in primary Wilms' tumors and their metastases and a study of the morphological effects of therapy. Virchows Arch A Pathol Anat Histopathol 1987;410:487-94.
39. Hard GC, Fox RR. Histologic characterization of renal tumors (nephroblastomas) induced transplacentally in III VO/J and WH/J rabbits by N-methylnitrosourea. Am J Pathol 1983;113:8-18.
40. Gerald WL, Miller HK, Battifora H, Miettinen M, Silva EG, Rosai J. Intra-abdominal desmoplastic small round-cell tumor. Am J Surg Path 1991;15:499-513.
41. Bacchi CE, Zarbo RJ, Jiang JJ, Gown AM. Do gliomas express cytokeratin? Appl Immunohistol 1995;3:45-53.