Solid phase synthesis of sec-amides and removal from the polymeric support under mild conditions

Tetrahedron Letters

Volumn 38, Issue 42, 1997, Pages 7325-7328

  Sarantakis, D ^a   Bicksler, J J ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENKEPHALIN DERIVATIVE; PEPTIDE DERIVATIVE;

ARTICLE; DRUG PURIFICATION; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; INFRARED SPECTROPHOTOMETRY; PEPTIDE SYNTHESIS; REACTION ANALYSIS; TECHNIQUE;

EID: 0030817703     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(97)01779-6     Document Type: Article

References (12)

1. Kornreich W.; Anderson H.; Porter J.; Vale W.; Rivier J.; Int.; J. Pept. Protein Res. (1985) 25 414.
2. Coy D.H.; Coy E.J.; Schally A.V.; Vipchez-Martinez J.A.; Debeljuk, L.; Cowter W.H.; Arimura A.; Biochemistry (1974) 13 323.
3. Jensen K.J.; Songster M.F.; Vagner J.; Alsina J.; Albericio F.; Barany G.; Peptides: Chem. Str. Biology Eds. Pravin T.P.; Kaumaya and Robert S. Hodges; Mayflower Scientific Ltd. (1996) p. 30.
4. Boojamra C.G.; Burow K.M.; Thompson L.A.; Ellman J.A.; J. Org. Chem. (1997) 62 1240.
5. Chan W.C.; Mellor S.L.; J. Chem. Soc., Chem. Commun. (1995) 1475.
6. 4-Hydroxy-2-methoxy benzaldehyde is commercially available from Lancaster Synthesis Inc.
7. -1.
8. -1.
9. Sarantakis D.; Teichman J.; Lien E.L.; Fenichel R.L.; Bioch. Biophys. Res. Commun. (1976) 73 336.
10. Chen F.M.F.; Kuroda K.; Benoiton N.L.; Synthesis (1978) 928.
11. Albericio F.; Barany G.; Int. J. Pept. Protein Res. (1987) 30 206.
12. Johnson T.; Quibell M.; Sheppard R.C.; J. Pept. Science (1995) 1 11.