Ex vivo culture of peripheral blood CD34+ cells: Effects of hematopoietic growth factors on production of neutrophilic precursors

Journal of Hematotherapy and Stem Cell Research

Volumn 6, Issue 5, 1997, Pages 475-489

  Makino, Shigeyoshi ^a   Haylock, David N ^b,d   Dowse, Tracey ^b   Trimboli, Sandra ^b   Niutta, Silvana ^b   To, Luen B ^b   Juttner, Christopher A ^c   Simmons, Paul J ^b  

^a MIYAZAKI PREFECTURAL MIYAZAKI HOSPITAL   (Japan)

^b INSTITUTE OF MEDICAL AND VETERINARY SCIENCE   (Australia)

^c NOVARTIS PHARMA AG   (Switzerland)

^d HANSON INSTITUTE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; CYCLOPHOSPHAMIDE; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; GROWTH FACTOR; INTERLEUKIN 1; INTERLEUKIN 3; INTERLEUKIN 6; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; STEM CELL FACTOR;

ANTIGEN EXPRESSION; ANTIGEN PRESENTING CELL; ARTICLE; DOSE RESPONSE; HEMATOPOIESIS; HUMAN; HUMAN CELL; HUMAN TISSUE; NEUTROPENIA; PERIPHERAL CIRCULATION; PRIORITY JOURNAL; PROMYELOCYTE; SUBCUTANEOUS DRUG ADMINISTRATION;

ANTIGENS, CD34; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CYTOKINES; HEMATOPOIETIC CELL GROWTH FACTORS; HEMATOPOIETIC STEM CELL MOBILIZATION; HEMATOPOIETIC STEM CELLS; HUMANS; NEUTROPHILS;

EID: 0030817406     PISSN: 15258165     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (53)

1. Berenson, R.J., Andrews, R.G., Bensinger, W.I., et al. Antigen CD34-positive marrow cells engraft lethally irradiated baboons. J. Clin. Invest. 81:951, 1988.
2. Wagemaker, G., Van Gils, F.C.J.M., Bart-Baumeister, J.A.K., et al. Sustained engraftment of allogeneic CD34 positive hemopoietic cells in rhesus monkeys. Exp. Hematol. 18:704, 1990.
3. Jones, R.J., Sharkis, S.J., Colvin, O.M., et al. Progenitor cell assays predict hemopoietic reconstitution after syngeneic transplantation in mice. Blood 70:1186, 1987.
4. Naparestek, E., Hardan, Y., Ben-Shahar, M., et al. Enhanced marrow recovery by short preincubation of marrow allografts with human recombinant interleukin-3 and granulocyte-macrophage colony-stimulating factor. Blood 80:1673, 1992.
5. Sutherland, H.J., Eaves, C.J., Eaves, A.C., et al. Characterization and partial purification of human marrow cells capable of initiating long-term hemopoiesis in vitro. Blood 74:1563, 1989.
6. Winton, E.F. & Colenda, K.W. Use of long-term human marrow cultures to demonstrate progenitor cell precursors in marrow treated with 4-hydroperoxycyclophosphamide. Exp. Hematol. 15:710, 1989.
7. Moore, M.A.S. Clinical implications of positive and negative hematopoietic stem cell regulators. Blood 78:1, 1991.
8. Brandt, J., Srour, E.F., van Besien, K., et al. Cytokine dependent long-term culture of highly enriched precursors of hemopoietic progenitor cells from human bone marrow. J. Clin. Invest. 86:932, 1990.
9. To, L.B., Robeerts, M., Haylock, D.N., et al. Comparison of hematological recovery times and supportive care requirements of autologous recovery phase peripheral blood stem cell transplants, autologous bone marrow transplants and allogeneic bone marrow transplants. Bone Marrow Transplant. 9:227, 1992.
10. Sheridan, W.P., Begley, C.G., Juttner, C.A., et al. Effect of peripheral blood progenitor cells mobilised by filgrastim (G-CSF) on platelet recovery after high-dose chemotherapy. Lancet 339:640, 1992.
11. Reiffers, J., Leverger, G., Marit, G., et al. Hematopoietic reconstitution after autologous blood stem cell transplantation. In Bone Marrow Transplant: Current Controversies. Proceedings of Sandoz-UCLA symposium eds. Gale, R.P. & Champlin, R.E. Alan R Liss, New York, 1988, p. 313.
12. To, L.B., Roberts, M.M., Rawling, C.M., et al. Establishment of a clinical threshold cell dose; correlation between CFU-GM and duration of aplasia. In Hematopoietic Stem Cells. The Mulhouse Manual, eds. Wunder, E., Sovalat, H., Henon, P.R., et al. Alpha Med Press, Dayton, 1994, p. 15.
13. Haylock, D.N., To, L.B., Dowse, T.L., et al. Ex vivo expansion and maturation of peripheral blood CD34+ cells into the myeloid lineage. Blood 80:1405, 1992.
14. Haylock, D.N., To, L.B., Makino, S., et al. Ex vivo expansion of human hemopoietic progenitors with cytokines. In Hemopoietic Stem Cells: Biology and Therapeutic Applications, eds. Levitt, D. & Mertelsmann, R. Marcel Dekker, New York, 1994, p. 491.
15. Muench, M.O. & Moore, M.A.S. Accelerated recovery of peripheral blood cell counts in mice transplanted with in vitro cytokine-expanded hematopoietic progenitors. Exp. Hematol. 20:611, 1992.
16. Shapiro, F., Yao, T.-Y., Raptis, G., et al. Optimization of conditions for ex vivo expansion of CD34+ cells from patients with stage IV breast cancer. Blood 84:3567, 1994.
17. Smith, S.L., Bender, J.G., Maples, P.B., et al. Expansion of neutrophil precursors and progenitors in suspension cultures of CD34+ cells enriched from human bone marrow. Exp. Hematol. 21:870, 1993.
18. To, L.B., Sheppard, K.M., Haylock, D.N., et al. Single high doses of cyclophosphamide enable the collection of high numbers of hemopoietic stem cells from the peripheral blood. Exp. Hematol. 18:442, 1990.
19. Philip, T., Cauvin, F., Armitage, J., et al. Parma international protocol: Pilot study of DHAP followed by involved-field ratiotherapy and BAEC with autologous bone marrow transplantation. Blood 77:1587, 1991.
20. To, L.B., Haylock, D.N., Thorp, D., et al. The optimization of collection of peripheral blood stem cells for transplantation in acute myeloid leukemia. Bone Marrow Transplant 4:41, 1989.
21. Andrews, R.G., Singer, J.W. & Bemstien, I.D. Presursors of colony-forming cells in humans can be distinguished from colony-forming cells by expression of the CD33 and CD34 antigens and light scatter properties. J. Exp. Med. 169:1721, 1989.
22. Dacie, J.V. & Lewis, S.M. Practical Haematology, 6th ed. Churchill Livingston, London, 1984.
23. Simmons, P.J., Kaushansky, K. & Torok-Storb, B. Mechanisms of cytomegalovirus-mediated myelosuppression: Perturbation of stromal cell function versus direct infection of myeloid cells. Proc. Natl. Acad. Sci. USA 87:1386, 1990.
24. Heimfeld, S., Fogarty, B., McGuire, K., et al. Peripheral blood stem cell mobilization after stem cell factor and G-CSF treatment: Rapid enrichment for stem and progenitor cells using CEPRATE/immunoaffinity separation system. Transplant. Proc. 24:2828, 1992.
25. Rebel, V., Dragowska, W., Eaves, C.J., et al. Amplification of Sca-1 + Lin - WGA+ cells in serum-free cultures containing steel factor, interleukin-6 and erythropoietin with maintenance of cells with long-term in vitro reconstituting potential. Blood 83:128, 1994.
26. Tsujino, Y., Wada, H., Misawa, M., et al. Effects of mast cell growth factor, interleukin-3, and interleukin-6 on human primitive hematopoietic progenitors from bone marrow and cord blood. Exp. Hematol. 21:1379, 1993.
27. Brugger, W., Mocklin, W., Heimfeld, S., et al. Ex vivo expansion of enriched peripheral blood CD34+ cells by stem cell factor, interleukin-1b, IL-6, IL-3, interferon-gamma and erythropoietin. Blood 81:2579, 1993.
28. Steen, R., Morkrid, L., Tjonnfjord, G.E., et al. c-Kit ligand combined with GM-CSF and/or IL-3 can expand CD34+ hematopoietic progenitor cells for several weeks in vitro. Stem Cells 12:214, 1994.
29. Loudovaris, M., Unverzagt, K., Smith, S., et al. Ex vivo expansion of neutrophil precursors from mobilized peripheral progenitor cells. Blood 86:584a (abstract), 1995.
30. Haylock, D.N., Makino, S., Dowse, T.L., et al. Ex vivo hematopoietic progenitor cell expansion. Immunomethods 5:217, 1994.
31. Haylock, D.N., To, L.B., Dowse, T.L., et al. Ex vivo expansion of hematopoietic stem cells. In Wunder E (ed) Hematopoietic Stem Cells. The Mulhouse Manual, ed. Wunder, E. Alpha Med Press, Dayton, 1994, p. 291.
32. Brandt, I.E., Bhalla, K. & Hoffman, R. Effects of interleukin-3 and c-kit ligand on the survival of various classes of human hematopoietic progenitor cells. Blood 83:1507, 1994.
33. Migliaccio, G., Migliaccio, A.R., Druzin, M.L., et al. Long-term generation of colony-forming cells in liquid culture of CD34+ cord blood cells in the presence of recombinant human stem cell factor. Blood 79:2620, 1992.
34. McNiece, I.K., Langley, K.E. & Zsebo, M. Recombinant human stem cell factor synergizes with GM-CSF, G-CSF, IL-3, and EPO to stimulate human progenitor cells of the myeloid and erythroid lineages. Exp. Hematol. 19:226, 1992.
35. Iscove, N.N., Shaw, A.R. & Keller, G. Net increase of pluripotential hematopoietic precursors in suspension culture to IL-1 and IL-3. J. Immunol. 14:2332, 1989.
36. Metcalf, D. Lineage commitment of hemopoietic progenitor cells in developing blast cell colonies: Influence of colony-stimulating factors. Proc. Natl. Acad. Sci. USA 88:11310, 1991.
37. Cassel, A., Cottler-Fox, M., Doren, S., et al. Retroviral-mediated gene transfer into CD34-enriched human peripheral blood stem cells. Exp. Hematol. 21:585, 1993.
38. Crooks, G.M. & Kohn, D.B. Growth factors increase amphotrophic retrovirus binding to human CD34H- bone marrow progenitor cells. Blood 82:3290, 1993.
39. Nolta, J.A., Crooks, G.M., Overell, R.W., et al. Retroviral vector-mediated gene transfer into primitive human hematopoietic progenitor cells: Effects of mast cell growth factor (MGF) combined with other cytokines. Exp. Hematol. 20:1065, 1992.
40. Lusky, B.D., Rosenblatt, M., Zsebo, K., et al. Stem cell factor, interleukin-3, and interleukin-6 promote retroviral-mediated gene transfer into murine hematopoietic stem cells. Blood 80:396, 1992.
41. Metcalf, D. & Nicola, N.A. Proliferative effects of purified granulocyte colony-stimulating factor (G-CSF) on normal mouse hemopoietic cells. J. Cell. Physiol. 116:198, 1983.
42. Demitri, G.D. & Griffin, J.D. Granulocyte colony-stimulating factor and its receptor. Blood 78:2791, 1991.
43. 0 and entry into the cell cycle of primitive human hemopoietic progenitors. Proc. Natl. Acad. Sci. USA 89:4013, 1992.
44. Ikebuchi, K., Clark, S.C., Ihle, J.N., et al. Granulocyte colony-stimulating factor enhances interleukin-3 dependent proliferation of multipotent hemopoietic progenitors. Proc. Natl. Acad. Sci. USA 85:3445, 1988.
45. Sato, N., Sawada, K., Koizumi, K., et al. In vitro expansion of human peripheral blood CD34+ cells. Blood 82:3600, 1993.
46. Walker, F., Nicola, N.A., Metcalf, D., et al. Hierarchical downmodulation of hemopoietic growth factor receptors. Cell 43:269, 1985.
47. Gliniak, B.C. & Rohrschneider, L.R. Expression of the M-CSF receptor is controlled post transcriptionally by the dominant actions of GM-CSF or multi-CSF. Cell 63:1073, 1990.
48. Nicola, N.A., Vadas, M.A. & Lopez, A.F. Down-modulation of the receptors for granulocyte colony-stimulating factor on human neutrophils by granulocyte-activating agents. J. Cell Physiol. 128:501, 1986.
49. Khwaja, A., Carver, J., Jones, H.M., et al. Expression and dynamic modulation of the human granulocyte colony-stimulating factor receptor in immature and differentiated myeloid cells. Br. J. Haematol. 85:254, 1993.
50. Kitamura, T., Takaku, F. & Miyajima, A. IL-1 up-regulates the expression of cytokine receptors on a factor-dependent human hemopoietic cell line, TF-1. Int. Immunol. 3:571, 1991.
51. Jacobsen, S.E.N., Ruscetti, F.W., Dubois, C.M., et al. Induction of colony-stimulating factor receptor expression on hematopoietic progenitor cells: Proposed mechanism for growth factor synergism. Blood 80:678, 1992.
52. Purdy, M.H., Hogan, C.J., Hami, L., et al. Large volume ex vivo expansion of CD34-positive hematopoietic progenitor cells for transplantation. J. Hematother. 4:515, 1995.
53. Williams, S.F., Lee, W.J., Bender, J.G., et al. Selection and expansion of peripheral blood CD34+ cells in autologous stem cell transplantation for breast cancer. Blood 87:1687, 1996.