Intratumoral differences in methotrexate levels within human osteosarcoma xenografts studied by microdialysis

Life Sciences

Volumn 61, Issue 19, 1997, Pages PL275-PL280

  Ekstrøm, Per Olaf ^a   Giercksky, Karl E ^a   Andersen, Anders ^a   Bruland, Øyvind S ^a   Slørdal, Lars ^b  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

^b Natl Inst of Forensic Toxicology   (Norway)

Author keywords

Methotrexate; Microdialysis; Nude rat; Osteosarcoma; Tissue; Xenograft

Indexed keywords

METHOTREXATE;

ARTICLE; CYTOTOXICITY; DRUG MONITORING; HUMAN; HUMAN CELL; MICRODIALYSIS; OSTEOSARCOMA; SOLID TUMOR; TREATMENT OUTCOME; TUMOR GROWTH; XENOGRAFT;

EID: 0030817367     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0024-3205(97)00839-4     Document Type: Article

References (20)

1. W.A. BLEYER, Cancer 41 36-51 (1978).
2. M. FLEISHER, Ther Drug Monit 15 521-526 (1993).
3. F. SJØQVIST, O. BORGÅ AND M.L.E. ORME, Fundamental of clinical pharmacology, G. S. Avery (Eds), 1-61, Publishe, Sydney (1980).
4. N. DELEPINE, G. DELEPINE, H. CORNILLE, F. BRION, P. ARNAUD AND J.C. DESBOIS, Anticancer Res 15 489-494 (1995).
5. N. DELEPINE, G. DELEPINE, B. GAETANO, G. ROSEN AND J.C. DESBOIS, Cancer 78 2127-2135 (1996).
6. R.K. JAIN, Cancer Res 47 3039-3051 (1987).
7. U. UNGERSTEDT, J Intern Med 230 365-373 (1991).
8. ANONYMOUS, Lancet 339 1326-1327 (1992).
9. P.O. EKSTRØM, A. ANDERSEN, D.J. WARREN, K.E. GIERCKSKY AND L. SLØRDAL, Cancer Chemother Pharmacol 34 297-301 (1994).
10. P.O. EKSTRØM, A. ANDERSEN, D.J. WARREN, K.E. GIERCKSKY AND L. SLØRDAL, Cancer Chemother Pharmacol 37 394-400 (1996).
11. P.O. EKSTRØM, A. ANDERSEN, D.J. WARREN, K.E. GIERCKSKY AND L. SLØRDAL, Cancer Chemother Pharmacol 36 283-289 (1995).
12. Ø. FODSTAD, A. BRØGGER, Ø. BRULAND, O.P. SOLHEIM, J.M. NESLAND AND A. PIHL, Int J Cancer 38 33-40 (1986).
13. J.A. MCATEER AND J. DAVIS, Basic cell culture technique and the maintenance of cell lines, J. M. Davis (Eds), Publishe, Oxford (1994).
14. P.O. EKSTRØM, A. ANDERSEN, G. SÆTER, K.E. GIERCKSKY AND L. SLØRDAL, Cancer Chemother Pharmacol 39 267-272 (1997).
15. P.O. EKSTRØM, K.E. GIERCKSKY, A. ANDERSEN AND L. SLØRDAL, Life Sci 60 PL 359-64(1997).
16. L. SLØRDAL, P.S. PRYTZ, I. PETTERSEN AND J. AARBAKKE, Ther Drug Monit 8 368-372 (1986).
17. R.K. JAIN, Sci Am 271 42-49 (1994).
18. H.F. DVORAK, L.F. BROWN, M. DETMAR AND A.M. DVORAK, Am J Pathol 146 1029-1039 (1995).
19. R.K. JAIN, Cancer Metastasis Rev 6 559-593 (1987).
20. P. GULLINO, Extracellular compartments of solid tumors, F. F. Becker (Eds), 327-354, Publishe, New York (1975).