Asymmetric Friedel-Crafts reaction mediated by new chiral auxiliaries derived from (1S)-(-)-β-Pinene: Enantioselective synthesis of(-)-8-Norethyl, 1'-Normethyl etodolac

Tetrahedron Letters

Volumn 38, Issue 40, 1997, Pages 7021-7024

  Costa, Paulo R R ^a   Cabral, Lúcio M ^a   Alencar, Karla G ^a   Schmidt, Luciana L ^a   Vasconcellos, Mário L A A ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ETODOLAC;

ARTICLE; CHIRALITY; DRUG SYNTHESIS; IN VITRO STUDY; REACTION ANALYSIS; STEREOCHEMISTRY;

EID: 0030817245     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(97)01658-4     Document Type: Article

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28. 3 ) δ 22.09, 22.80, 24.83, 25.04, 27.15, 30.89, 32.55, 35.76, 38.28, 40.50,45.10, 45.84, 54.73, 60.31, 72.09, 76.66, 106.30, 110.10, 117.90, 119.00, 121.50, 113.4, 123.30, 129.10, 132.00, 135.40, 137.00, 171.60; (172.00,minor epimer).
29. 3, Found 245.104978
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